Harry Wheeler has the highest ERA with 1.0+ inning pitched in a season, with an ERA of 81.00 in 1879.
| NAME | ERA | IP | SEASON | TM | G | W | L | W% | GS | SO | CG | SHO | SV | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | H. Wheeler | 81.00 | 1.0 | 1879 | CIN | 1 | 0 | 1 | .000 | 1 | 0 | 0 | 0 | 0 | 6 | 9 | 10 | 0 | 4 | 0 | 13 | 1 | 0.00 | 36.00 | 0.00 | 0.00 | 0.0 | 30.8 | 10.00 | 90.00 | 3415 | 14.74 | 621 | 54.00 | -1.5 | |||
| 2 | | E. Rivera | 72.00 | 1.0 | 2025 |  BAL | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 8 | 8 | 1 | 2 | 0 | 1 | 0 | 13 | 0 | 0.00 | 18.00 | 0.00 | 9.00 | 0.0 | 15.4 | 10.00 | .700 | 72.00 | 1830 | 22.08 | 551 | 72.00 | -2.1 | |
| 3 | | R. Liz | 67.50 | 1.1 | 2009 | BAL | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 8 | 10 | 10 | 1 | 2 | 2 | 0 | 0 | 16 | 0 | 6.75 | 13.50 | 0.50 | 6.75 | 6.3 | 12.5 | 7.50 | .700 | 67.50 | 1487 | 20.34 | 444 | 54.00 | -2.2 | |
| 4 | | M. Zagurski | 63.00 | 1.0 | 2018 |  MIL | 2 | 0 | 1 | .000 | 0 | 2 | 0 | 0 | 0 | 5 | 7 | 7 | 0 | 2 | 0 | 0 | 1 | 10 | 0 | 18.00 | 18.00 | 1.00 | 0.00 | 20.0 | 20.0 | 7.00 | .833 | 63.00 | 1566 | 5.16 | 127 | 45.00 | -0.1 |
| 5 | | G. Sparkman | 63.00 | 1.0 | 2017 |  TOR | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 9 | 7 | 7 | 0 | 1 | 0 | 1 | 0 | 12 | 0 | 9.00 | 9.00 | 1.00 | 0.00 | 8.3 | 8.3 | 10.00 | .900 | 63.00 | 1443 | 4.15 | 94 | 81.00 | 0 | |
| 6 | | J. Pearson | 63.00 | 1.0 | 2003 |  STL | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 7 | 7 | 1 | 3 | 0 | 0 | 0 | 10 | 0 | 9.00 | 27.00 | 0.33 | 9.00 | 10.0 | 30.0 | 7.00 | .600 | 63.00 | 1503 | 23.02 | 542 | 36.00 | -2.1 | |
| 7 | | M. Mahler | 63.00 | 1.0 | 1980 |  PIT | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 7 | 7 | 1 | 3 | 0 | 1 | 0 | 10 | 0 | 9.00 | 27.00 | 0.33 | 9.00 | 10.0 | 30.0 | 7.00 | .600 | 63.00 | 1682 | 22.74 | 618 | 36.00 | -2.1 | |
| 8 | | F. Schneiberg | 63.00 | 1.0 | 1910 |  BKN | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 7 | 8 | 0 | 4 | 0 | 0 | 12 | 0 | 0.00 | 36.00 | 0.00 | 0.00 | 0.0 | 33.3 | 9.00 | .625 | 72.00 | 2148 | 14.32 | 501 | 45.00 | -1.3 | ||
| 9 | | J. Garry | 63.00 | 1.0 | 1893 |  BSN | 1 | 0 | 1 | .000 | 0 | 2 | 0 | 0 | 0 | 5 | 7 | 8 | 0 | 4 | 0 | 0 | 12 | 0 | 18.00 | 36.00 | 0.50 | 0.00 | 16.7 | 33.3 | 9.00 | .833 | 72.00 | 1300 | 11.24 | 232 | 45.00 | -0.7 | |
| 10 | | (. Lewis | 60.00 | 3.0 | 1890 | BUF | 1 | 0 | 1 | .000 | 1 | 1 | 0 | 0 | 0 | 13 | 20 | 20 | 3 | 7 | 0 | 0 | 29 | 1 | 3.00 | 21.00 | 0.14 | 9.00 | 3.4 | 24.1 | 6.67 | .556 | 60.00 | 1448 | 22.25 | 540 | 39.00 | -6.2 | |
| 11 | | J. Caballero | 54.00 | 1.0 | 2025 |  TBR | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 6 | 6 | 2 | 1 | 0 | 1 | 0 | 9 | 0 | 0.00 | 9.00 | 0.00 | 18.00 | 0.0 | 11.1 | 6.00 | .500 | 54.00 | 1401 | 32.08 | 809 | 45.00 | -3.2 | |
| 12 | | L. Gilbreath | 54.00 | 1.0 | 2024 |  COL | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 6 | 6 | 1 | 1 | 1 | 0 | 0 | 12 | 0 | 0.00 | 9.00 | 0.00 | 9.00 | 0.0 | 8.3 | 8.00 | .667 | 54.00 | 1157 | 22.16 | 520 | 63.00 | -1.9 | |
| 13 | | M. Grace | 54.00 | 1.0 | 2020 |  ARI | 3 | 0 | 1 | .000 | 0 | 2 | 0 | 0 | 0 | 5 | 6 | 6 | 1 | 2 | 0 | 1 | 0 | 10 | 0 | 18.00 | 18.00 | 1.00 | 9.00 | 20.0 | 20.0 | 7.00 | .800 | 54.00 | 1197 | 18.18 | 417 | 45.00 | -1.6 |
| 14 | | C. Carroll | 54.00 | 2.0 | 2020 | BAL | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 9 | 12 | 12 | 0 | 5 | 1 | 0 | 0 | 21 | 2 | 13.50 | 22.50 | 0.60 | 0.00 | 14.3 | 23.8 | 7.00 | .750 | 54.00 | 1197 | 9.18 | 195 | 40.50 | -0.9 | |
| 15 | | J. Reyes | 54.00 | 1.0 | 2018 |  NYM | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 6 | 6 | 2 | 2 | 1 | 1 | 0 | 11 | 0 | 0.00 | 18.00 | 0.00 | 18.00 | 0.0 | 18.2 | 7.00 | .500 | 54.00 | 1413 | 38.16 | 959 | 45.00 | -3.9 | |
| 16 | | V. Mazzaro | 54.00 | 1.0 | 2016 |  SFG | 2 | 1 | 0 | 1.000 | 0 | 0 | 0 | 0 | 0 | 7 | 6 | 9 | 0 | 1 | 1 | 0 | 0 | 13 | 0 | 0.00 | 9.00 | 0.00 | 0.00 | 0.0 | 7.7 | 8.00 | .636 | 81.00 | 1337 | 9.14 | 233 | 63.00 | -0.6 |
| 17 | | J. Wall | 54.00 | 1.0 | 2014 |  LAA | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 6 | 6 | 0 | 3 | 0 | 1 | 0 | 11 | 0 | 0.00 | 27.00 | 0.00 | 0.00 | 0.0 | 27.3 | 8.00 | .625 | 54.00 | 1490 | 12.13 | 330 | 45.00 | -1 | |
| 18 | | S. Rosario | 54.00 | 1.0 | 2010 |  FLA | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 6 | 6 | 2 | 1 | 0 | 0 | 0 | 12 | 0 | 0.00 | 9.00 | 0.00 | 18.00 | 0.0 | 8.3 | 10.00 | .778 | 54.00 | 1332 | 32.07 | 820 | 81.00 | -3.2 | |
| 19 | | J. Fernandez | 54.00 | 1.0 | 2004 |  HOU | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6 | 6 | 6 | 0 | 5 | 0 | 0 | 0 | 14 | 0 | 0.00 | 45.00 | 0.00 | 0.00 | 0.0 | 35.7 | 11.00 | .667 | 54.00 | 1242 | 18.04 | 406 | 54.00 | -1.5 | |
| 20 | | D. Maurer | 54.00 | 1.1 | 2004 |  TOR | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 6 | 8 | 8 | 1 | 5 | 0 | 0 | 0 | 15 | 0 | 6.75 | 33.75 | 0.20 | 6.75 | 6.7 | 33.3 | 8.25 | .625 | 54.00 | 1132 | 22.54 | 489 | 40.50 | -2.6 | |
| 21 | | G. Pladson | 54.00 | 1.1 | 1982 |  HOU | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 8 | 8 | 0 | 2 | 0 | 1 | 0 | 16 | 0 | 0.00 | 13.50 | 0.00 | 0.00 | 0.0 | 12.5 | 9.00 | .714 | 54.00 | 1595 | 7.21 | 215 | 67.50 | -0.6 | |
| 22 | | V. Valentinetti | 54.00 | 1.0 | 1954 |  CWS | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 6 | 6 | 1 | 2 | 0 | 1 | 9 | 0 | 9.00 | 18.00 | 0.50 | 9.00 | 11.1 | 22.2 | 6.00 | .600 | 54.00 | 1450 | 19.40 | 518 | 36.00 | -1.7 | ||
| 23 | | W. Wietelmann | 54.00 | 1.0 | 1945 |  BSN | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 6 | 6 | 0 | 2 | 0 | 1 | 11 | 0 | 0.00 | 18.00 | 0.00 | 0.00 | 0.0 | 18.2 | 8.00 | .667 | 54.00 | 1421 | 8.54 | 231 | 54.00 | -0.5 | ||
| 24 | | M. Lang | 54.00 | 1.2 | 1930 |  PIT | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 9 | 10 | 10 | 2 | 3 | 0 | 0 | 16 | 1 | 10.80 | 16.20 | 0.67 | 10.80 | 12.5 | 18.8 | 7.20 | .778 | 54.00 | 1075 | 22.10 | 445 | 48.60 | -3.1 | ||
| 25 | | J. Ogrodowski | 54.00 | 1.0 | 1925 |  BSN | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 6 | 8 | 0 | 3 | 0 | 0 | 13 | 0 | 0.00 | 27.00 | 0.00 | 0.00 | 0.0 | 23.1 | 9.00 | .600 | 72.00 | 1332 | 12.11 | 299 | 54.00 | -0.9 | ||
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