Since 2001, Max Scherzer has the highest Game Score, with a Game Score of 104 against the Mets on October 3, 2015.

Interpreted as:

highest game score by a player after 2000

	NAME	GSC	DATE	TM		OPP	DEC	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP
1	Max Scherzer M. Scherzer	104	10/3/2015	WSH	@	NYM	W	1	0.00	17	1	1	0	9.0	0	0	0	0	0	0	0	0	28	0
2	Clayton Kershaw C. Kershaw	102	6/18/2014	LAD	vs	COL	W	1	0.00	15	1	1	0	9.0	0	0	0	0	0	0	0	0	28	0
3	Matt Cain M. Cain	101	6/13/2012	SFG	vs	HOU	W	1	0.00	14	1	1	0	9.0	0	0	0	0	0	0	0	0	27	0
4	Justin Verlander J. Verlander	100	9/1/2019	HOU	@	TOR	W	1	0.00	14	1	1	0	9.0	0	0	0	0	1	0	0	0	28	0
5	Gerrit Cole G. Cole	100	5/4/2018	HOU	@	ARI	W	1	0.00	16	1	1	0	9.0	1	0	0	0	1	0	0	0	29	0
6	Max Scherzer M. Scherzer	100	6/14/2015	WSH	@	MIL	W	1	0.00	16	1	1	0	9.0	1	0	0	0	1	0	0	0	29	0
7	Brandon Morrow B. Morrow	100	8/8/2010	TOR	vs	TBR	W	1	0.00	17	1	1	0	9.0	1	0	0	0	2	0	0	0	31	0
8	Randy Johnson R. Johnson	100	5/18/2004	ARI	@	ATL	W	1	0.00	13	1	1	0	9.0	0	0	0	0	0	0	0	0	27	0
9	Curt Schilling C. Schilling	100	4/7/2002	ARI	@	MIL	W	1	0.00	17	1	1	0	9.0	1	0	0	0	2	0	0	0	29	0
10	John Means J. Means	99	5/5/2021	BAL	@	SEA	W	1	0.00	12	1	1	0	9.0	0	0	0	0	0	0	0	0	27	1
11	Lucas Giolito L. Giolito	99	8/25/2020	CWS	vs	PIT	W	1	0.00	13	1	1	0	9.0	0	0	0	0	1	0	0	0	28	0
12	Felix Hernandez F. Hernandez	99	8/15/2012	SEA	vs	TBR	W	1	0.00	12	1	1	0	9.0	0	0	0	0	0	0	0	0	27	0
13	Hideo Nomo H. Nomo	99	5/25/2001	BOS	vs	TOR	W	1	0.00	14	1	1	0	9.0	1	0	0	0	0	0	0	0	28	0
14	Jacob deGrom J. deGrom	98	4/23/2021	NYM	vs	WSH	W	1	0.00	15	1	1	0	9.0	2	0	0	0	0	0	0	0	29	0
15	Madison Bumgarner M. Bumgarner	98	7/10/2016	SFG	vs	ARI	W	1	0.00	14	1	1	0	9.0	1	0	0	0	1	0	0	0	28	0
16	Carlos Carrasco C. Carrasco	98	9/25/2015	CLE	@	KCR	W	1	0.00	15	1	1	0	9.0	1	0	0	0	2	0	0	0	29	0
17	Jake Arrieta J. Arrieta	98	8/30/2015	CHC	@	LAD	W	1	0.00	12	1	1	0	9.0	0	0	0	0	1	0	0	0	29	0
18	Cole Hamels C. Hamels	98	7/25/2015	PHI	@	CHC	W	1	0.00	13	1	1	0	9.0	0	0	0	0	2	0	0	0	29	0
19	Chris Heston C. Heston	98	6/9/2015	SFG	@	NYM	W	1	0.00	11	1	1	0	9.0	0	0	0	0	0	3	0	0	29	0
20	Corey Kluber C. Kluber	98	5/13/2015	CLE	vs	STL	W	1	0.00	18	0	0	0	8.0	1	0	0	0	0	1	0	0	26	0
21	Madison Bumgarner M. Bumgarner	98	8/26/2014	SFG	vs	COL	W	1	0.00	13	1	1	0	9.0	1	0	0	0	0	0	0	0	28	0
22	Shelby Miller S. Miller	98	5/10/2013	STL	vs	COL	W	1	0.00	13	1	1	0	9.0	1	0	0	0	0	0	0	0	28	0
23	Roy Halladay R. Halladay	98	5/29/2010	PHI	@	FLA	W	1	0.00	11	1	1	0	9.0	0	0	0	0	0	0	0	0	27	0
24	Jonathan Sanchez J. Sanchez	98	7/10/2009	SFG	vs	SDP	W	1	0.00	11	1	1	0	9.0	0	0	0	0	0	0	0	0	28	1
25	Erik Bedard E. Bedard	98	7/7/2007	BAL	@	TEX	W	1	0.00	15	1	1	0	9.0	2	0	0	0	0	0	0	0	27	0