The Chicago Cubs have the highest run differential by a team this season, with a differential of 62 runs.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cubs	62	2025	33	.606	20	13	1,167	202	310	63	9	49	198	132	10	261	44	6	1,324	538	121	5	10	3	12	.266	.343	.461	.804
2	Mets	58	2025	33	.667	22	11	1,107	159	277	62	8	38	152	117	18	247	19	5	1,254	469	108	0	12	6	25	.250	.329	.424	.752
3	Tigers	54	2025	33	.636	21	12	1,110	164	280	43	6	43	159	121	12	301	15	2	1,256	464	92	4	9	3	16	.252	.330	.418	.748
4	Yankees	54	2025	33	.576	19	14	1,121	182	294	58	5	56	176	128	18	304	23	10	1,277	530	119	0	10	5	18	.262	.345	.473	.817
5	Reds	42	2025	33	.545	18	15	1,111	169	276	52	2	35	163	120	15	276	36	10	1,255	437	89	2	7	3	18	.248	.328	.393	.721
6	Dodgers	36	2025	32	.688	22	10	1,064	169	271	50	6	51	163	121	11	261	23	6	1,208	486	107	1	11	3	24	.255	.334	.457	.791
7	Mariners	35	2025	31	.613	19	12	1,049	165	259	40	2	48	157	137	20	271	37	12	1,218	447	90	5	7	3	16	.247	.343	.426	.769
8	Padres	34	2025	32	.656	21	11	1,040	129	269	47	3	28	118	101	9	219	29	9	1,168	406	78	9	9	4	22	.259	.327	.390	.717
9	Giants	29	2025	34	.618	21	13	1,114	155	253	55	5	35	146	125	7	291	21	8	1,257	423	95	4	7	2	16	.227	.307	.380	.687
10	Red Sox	18	2025	35	.514	18	17	1,216	175	311	69	5	41	166	131	14	322	42	7	1,370	513	115	1	8	9	17	.256	.333	.422	.755
11	Astros	14	2025	32	.531	17	15	1,062	128	256	43	4	28	121	101	12	259	21	7	1,189	391	75	5	9	5	23	.241	.312	.368	.680
12	Phillies	10	2025	33	.576	19	14	1,112	150	280	50	6	31	140	129	12	258	30	6	1,262	435	87	2	7	6	24	.252	.334	.391	.725
13	Brewers	6	2025	33	.485	16	17	1,103	159	267	43	4	27	141	117	16	262	40	10	1,255	399	74	9	10	5	19	.242	.321	.362	.683
14	Diamondbacks	4	2025	33	.515	17	16	1,110	165	272	67	6	43	160	131	13	255	28	6	1,275	480	116	6	15	4	22	.245	.328	.432	.760
15	Rays	1	2025	33	.455	15	18	1,097	124	263	51	3	27	119	104	8	274	39	6	1,219	401	81	0	10	0	28	.240	.308	.366	.673
16	Braves	0	2025	31	.452	14	17	1,044	128	251	45	2	36	122	109	7	265	19	4	1,166	408	83	2	4	0	21	.240	.315	.391	.706
17	Twins	0	2025	34	.412	14	20	1,126	128	265	60	4	27	122	98	21	270	20	7	1,253	414	91	0	8	1	21	.235	.306	.368	.674
18	Cardinals	-4	2025	33	.424	14	19	1,135	150	291	65	1	30	141	116	10	254	27	7	1,271	448	96	3	7	8	29	.256	.329	.395	.724
19	Royals	-8	2025	33	.515	17	16	1,083	105	250	56	4	15	105	88	12	235	26	13	1,201	359	75	5	13	5	13	.231	.293	.331	.624
20	Athletics	-23	2025	34	.529	18	16	1,157	147	293	51	5	45	140	104	3	252	11	5	1,274	489	101	2	8	0	31	.253	.314	.423	.737
21	Guardians	-24	2025	33	.576	19	14	1,068	126	246	42	2	38	119	101	12	268	24	8	1,202	406	82	5	16	5	17	.230	.300	.380	.680
22	Rangers	-24	2025	33	.485	16	17	1,060	104	239	46	3	31	102	74	9	263	27	7	1,152	384	80	2	7	2	20	.225	.280	.362	.642
23	White Sox	-25	2025	33	.273	9	24	1,071	119	230	42	1	26	116	115	8	282	23	7	1,206	352	69	4	8	1	18	.215	.294	.329	.622
24	Blue Jays	-32	2025	33	.485	16	17	1,095	116	261	55	1	23	111	105	14	239	23	8	1,230	387	79	5	11	4	23	.238	.310	.353	.664
25	Nationals	-36	2025	33	.424	14	19	1,089	136	256	44	6	34	127	99	10	267	32	10	1,210	414	84	6	6	0	16	.235	.303	.380	.683