highest run differential in season with 100 wins 2000 to 2015

Between the 2000 and 2015 seasons, the Seattle Mariners had the highest run differential by a team with 100+ wins in a season, with a differential of 300 runs in 2001.

Interpreted as:

highest run differential in season with 100 or more wins 2000 to 2015

	TEAM	DIFF	W	SEASON	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Mariners	300	116	2001	46	.716	162	5,680	927	1,637	310	38	169	881	614	62	989	174	42	6,474	2,530	517	48	70	54	112	.288	.360	.445	.805
2	Athletics	239	102	2001	60	.630	162	5,573	884	1,469	334	22	199	835	640	88	1,021	68	29	6,385	2,444	555	25	59	57	131	.264	.345	.439	.784
3	Yankees	200	103	2002	58	.640	161	5,601	897	1,540	314	12	223	857	640	72	1,171	100	38	6,377	2,547	549	23	41	48	150	.275	.354	.455	.809
4	Cardinals	196	105	2004	57	.648	162	5,555	855	1,544	319	24	214	817	548	51	1,085	111	47	6,297	2,553	557	73	70	64	121	.278	.344	.460	.804
5	Phillies	184	102	2011	60	.630	162	5,579	713	1,409	258	38	153	693	539	56	1,024	96	24	6,277	2,202	449	65	38	52	108	.253	.323	.395	.717
6	Cardinals	171	100	2005	62	.617	162	5,538	805	1,494	287	26	170	757	534	62	947	83	36	6,246	2,343	483	77	35	60	127	.270	.339	.423	.762
7	Braves	167	101	2003	61	.623	162	5,670	907	1,608	321	31	235	872	545	49	933	68	22	6,378	2,696	587	65	49	46	124	.284	.349	.475	.824
8	Yankees	162	103	2009	59	.636	162	5,660	915	1,604	325	21	244	881	663	54	1,014	111	28	6,447	2,703	590	31	39	35	144	.283	.362	.478	.839
9	Yankees	161	101	2003	61	.623	163	5,605	877	1,518	304	14	230	845	684	81	1,042	98	33	6,430	2,540	548	25	35	54	154	.271	.356	.453	.810
10	Athletics	146	103	2002	59	.636	162	5,558	800	1,450	279	28	205	772	609	68	1,008	46	20	6,291	2,400	512	20	36	37	128	.261	.339	.432	.771
11	Braves	143	101	2002	59	.631	161	5,495	708	1,428	280	25	164	669	558	54	1,028	76	39	6,223	2,250	469	67	49	68	147	.260	.331	.409	.741
12	Cardinals	122	100	2015	62	.617	162	5,484	647	1,386	288	39	137	619	506	66	1,267	69	38	6,137	2,163	464	39	42	47	128	.253	.321	.394	.716
13	Giants	117	100	2003	61	.621	161	5,456	755	1,440	281	29	180	713	593	40	980	53	37	6,204	2,319	490	76	39	79	130	.264	.338	.425	.763
14	Yankees	89	101	2004	61	.623	162	5,527	897	1,483	281	20	242	863	670	80	982	84	33	6,364	2,530	543	37	50	40	157	.268	.353	.458	.811
15	Angels	68	100	2008	62	.617	162	5,540	765	1,486	274	25	159	721	481	52	987	129	48	6,155	2,287	458	32	50	52	140	.268	.330	.413	.743