Rogers Hornsby has the highest slugging percentage by a second baseman in a season, with a slugging percentage of .756 in 1925.

Interpreted as:

highest slg with a minimum of 3.1 PA per team game by 2b in a season

	NAME	SLG	SEASON	TM	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Rogers Hornsby R. Hornsby	.756	1925	SLN	138	504	133	203	41	10	39	143	83	2	39	5	3	605	381	90	16				.403	.489	1.245	173	94.1	.540	208	90.1
2	Rogers Hornsby R. Hornsby	.722	1922	SLN	154	623	141	250	46	14	42	152	65	1	50	17	12	704	450	102	15				.401	.459	1.181	186	97.8	.520	197	92.7
3	Rogers Hornsby R. Hornsby	.696	1924	SLN	143	536	121	227	43	14	25	94	89	2	32	5	12	640	373	82	13				.424	.507	1.203	175	96.7	.537	221	95.9
4	Rogers Hornsby R. Hornsby	.679	1929	CHC	156	602	156	229	47	8	39	149	87	1	65	2		712	409	94	22				.380	.459	1.139	181	86.8	.497	174	77.3
5	Nap Lajoie N. Lajoie	.643	1901	PHA	131	544	145	232	48	14	14	125	24	13	9	27		582	350	76	1				.426	.463	1.106	157	81	.506	186	71.5
6	Rogers Hornsby R. Hornsby	.639	1921	SLN	154	592	131	235	44	18	21	126	60	7	48	13	13	674	378	83	15				.397	.458	1.097	162	77.5	.489	191	77.7
7	Rogers Hornsby R. Hornsby	.632	1928	BSN	140	486	99	188	42	7	21	94	107	1	41	5		619	307	70	25				.387	.498	1.130	156	80.2	.506	196	78.1
8	Rogers Hornsby R. Hornsby	.627	1923	SLN	107	424	89	163	32	10	17	83	55	3	29	3	7	487	266	59	5				.384	.459	1.086	116	55.4	.490	184	53.3
9	Fred Dunlap F. Dunlap	.621	1884	SLU	101	449	160	185	39	8	13		29					478	279	60					.412			143	73.6	.477	215	77.7
10	Jeff Kent J. Kent	.596	2000	SFG	159	587	114	196	41	7	33	125	90	9	107	12	9	695	350	81	0	9	6	17	.334	.424	1.021	146	54.8	.431	158	55.1
11	Daniel Murphy D. Murphy	.595	2016	WSH	142	531	88	184	47	5	25	104	35	8	57	5	3	582	316	77	0	8	10	4	.347	.390	.985	112	43.4	.408	154	38.9
12	Ross Barnes R. Barnes	.590	1876	CWS	66	322	126	138	21	14	1	59	20		8			342	190	36					.429			105	53.2	.478	197	50.5
13	DJ LeMahieu	.590	2020	NYY	50	195	41	71	10	2	10	27	18	2	21	3	0	216	115	22	0	1	0	3	.364	.421	1.011	47	19.8	.429	177	20.6
14	Rogers Hornsby R. Hornsby	.586	1927	NYG	155	568	133	205	32	9	26	125	86	4	38	9		684	333	67	26				.361	.448	1.035	151	67.4	.469	176	65.8
15	Bret Boone B. Boone	.578	2001	SEA	158	623	118	206	37	3	37	141	40	9	110	5	5	690	360	77	5	13	5	11	.331	.372	.950	126	40.5	.397	149	42.5
16	Joe Morgan J. Morgan	.576	1976	CIN	141	472	113	151	30	5	27	111	114	1	41	60	9	599	272	62	0	12	8	2	.320	.444	1.020	123	60.3	.454	184	55.8
17	Chase Utley C. Utley	.566	2007	PHI	132	530	104	176	48	5	22	103	50	25	89	9	1	613	300	75	1	7	1	7	.332	.410	.976	121	45.1	.419	149	39.1
18	Jeff Kent J. Kent	.565	2002	SFG	152	623	102	195	42	2	37	108	52	4	101	5	1	682	352	81	0	3	3	20	.313	.368	.933	122	40.2	.397	147	40.1
19	Tony Lazzeri T. Lazzeri	.561	1929	NYY	147	545	101	193	37	11	18	106	68	4	45	9	10	635	306	66	18				.354	.429	.991	132	48.5	.443	158	50.2
20	Ketel Marte K. Marte	.560	2024	ARI	136	504	93	147	23	2	36	95	65	5	106	7	1	583	282	61	0	9	7	9	.292	.372	.932	106	37.9	.391	151	35.7
21	Ryne Sandberg R. Sandberg	.559	1990	CHC	155	615	116	188	30	3	40	100	50	1	84	25	7	675	344	73	0	9	8	8	.306	.354	.913	116	40.3	.396	142	33.3
22	Rogers Hornsby R. Hornsby	.559	1920	SLN	149	589	96	218	44	20	9	94	60	3	50	12	15	660	329	73	8				.370	.431	.990	135	59.4	.455	187	63.2
23	Jay Bell J. Bell	.557	1999	ARI	151	589	132	170	32	6	38	112	82	4	132	7	4	688	328	76	4	9	2	9	.289	.374	.931	122	32.3	.395	129	26.8
24	Charlie Gehringer C. Gehringer	.555	1936	DET	154	641	144	227	60	12	15	116	83	4	13	4	1	731	356	87	3				.354	.431	.987	154	58.5	.445	139	43.7
25	Jeff Kent J. Kent	.555	1998	SFG	137	526	94	156	37	3	31	128	48	9	110	9	4	594	292	71	1	10	4	16	.297	.359	.914	101	27.5	.387	138	28.8