| TEAM | OPPONENT | DATE | TIME (ET) | SPREAD | OVER/UNDER | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cincinnati Reds | -130 | @ |  Pittsburgh Pirates | +107 | Wed, May 21, 2025 | 12:35 PM | -1.5 | 8.0 |
| 2 |  | Houston Astros | -164 | @ |  Tampa Bay Rays | +138 | Wed, May 21, 2025 | 1:10 PM | -1.5 | 8.5 |
| 3 |  | Chicago Cubs | -148 | @ |  Miami Marlins | +124 | Wed, May 21, 2025 | 1:10 PM | -1.5 | 9.0 |
| 4 |  | Baltimore Orioles | -108 | @ |  Milwaukee Brewers | -113 | Wed, May 21, 2025 | 1:10 PM | -1.5 | 8.5 |
| 5 |  | Detroit Tigers | -104 | @ |  St. Louis Cardinals | -116 | Wed, May 21, 2025 | 1:15 PM | -1.5 | 9.0 |
| 6 |  | Seattle Mariners | -151 | @ |  Chicago White Sox | +127 | Wed, May 21, 2025 | 2:10 PM | -1.5 | 8.5 |
| 7 |  | Cleveland Guardians | +104 | @ |  Minnesota Twins | -123 | Wed, May 21, 2025 | 3:40 PM | -1.5 | 7.5 |
| 8 |  | Kansas City Royals | +179 | @ |  San Francisco Giants | -217 | Wed, May 21, 2025 | 3:45 PM | +1.5 | 7.5 |
| 9 |  | New York Mets | +124 | @ |  Boston Red Sox | -148 | Wed, May 21, 2025 | 6:45 PM | +1.5 | 7.5 |
| 10 |  | Atlanta Braves | -158 | @ |  Washington Nationals | +133 | Wed, May 21, 2025 | 6:45 PM | -1.5 | 8.5 |
| 11 |  | Texas Rangers | -103 | @ |  New York Yankees | -117 | Wed, May 21, 2025 | 7:05 PM | -1.5 | 7.5 |
| 12 |  | San Diego Padres | +140 | @ |  Toronto Blue Jays | -166 | Wed, May 21, 2025 | 7:07 PM | +1.5 | 8.5 |
| 13 |  | Philadelphia Phillies | -221 | @ |  Colorado Rockies | +182 | Wed, May 21, 2025 | 8:40 PM | -1.5 | 11.5 |
| 14 |  | Los Angeles Angels | +144 | @ |  Athletics | -172 | Wed, May 21, 2025 | 10:05 PM | +1.5 | 10.5 |
| 15 |  | Arizona Diamondbacks | +120 | @ |  Los Angeles Dodgers | -142 | Wed, May 21, 2025 | 10:10 PM | +1.5 | 9.0 |
| 16 | | Texas Rangers | +134 | @ | New York Yankees | -158 | Thu, May 22, 2025 | 12:35 PM | +1.5 | 7.5 |
| 17 | | San Diego Padres | -109 | @ | Toronto Blue Jays | -109 | Thu, May 22, 2025 | 1:07 PM | -1.5 | 8.5 |
| 18 | | Philadelphia Phillies | -287 | @ | Colorado Rockies | +230 | Thu, May 22, 2025 | 3:10 PM | -1.5 | 11.5 |
| 19 | | Los Angeles Angels | +128 | @ | Athletics | -152 | Thu, May 22, 2025 | 3:35 PM | +1.5 | 10.0 |
| 20 | | Cleveland Guardians | +124 | @ |  Detroit Tigers | -147 | Thu, May 22, 2025 | 6:40 PM | +1.5 | 8.0 |
| 21 |  | Milwaukee Brewers | -124 | @ | Pittsburgh Pirates | +106 | Thu, May 22, 2025 | 6:40 PM | -1.5 | 9.0 |
| 22 | | Baltimore Orioles | -104 | @ | Boston Red Sox | -112 | Thu, May 22, 2025 | 6:45 PM | -1.5 | 8.5 |
| 23 | | Atlanta Braves | -156 | @ | Washington Nationals | +131 | Thu, May 22, 2025 | 6:45 PM | -1.5 | 7.5 |
| 24 | | Seattle Mariners | -127 | @ |  Houston Astros | +109 | Thu, May 22, 2025 | 8:10 PM | -1.5 | 8.0 |
Betting lines shown represent consensus, closing odds.
Cubs 
Reds 
KCR 
Mariners 
Phillies 
Mets 
TEX 
SDP 
CLE 
ATL 
