highest strikeout percentage by mlb pitcher career with at least 500 games

Edwin Díaz has the best strikeout percentage when pitching in 500+ games, with a strikeout percentage of 39.9.

	NAME	K%	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Edwin Díaz E. Díaz	39.9	520	28	36	.438	0	2.82	839	0	0	253	519.1	356	163	176	54	182	40	395	9	2,105	33	14.54	3.15	4.61	0.94	8.6	1.04	.305	3.05	70	2.55	61	6.17	93.4
2	Aroldis Chapman A. Chapman	39.8	863	60	47	.561	0	2.52	1,331	0	0	367	821.1	475	230	255	54	408	33	563	7	3,341	87	14.58	4.47	3.26	0.59	12.2	1.08	.278	2.79	61	2.36	57	5.20	161.8
3	Craig Kimbrel C. Kimbrel	38.8	851	56	48	.538	0	2.58	1,282	0	0	440	821.2	492	236	263	75	346	40	656	11	3,306	70	14.04	3.79	3.71	0.82	10.5	1.02	.267	2.88	63	2.60	64	5.39	131.8
4	Kenley Jansen K. Jansen	34.7	934	54	40	.574	0	2.57	1,278	0	0	475	927.1	610	265	284	88	282	32	700	20	3,680	21	12.40	2.74	4.53	0.85	7.7	0.96	.261	2.76	65	2.62	64	5.92	147.2
5	Billy Wagner B. Wagner	33.2	853	47	40	.540	0	2.31	1,196	0	0	422	903.0	601	232	262	82	300	33	703	26	3,600	43	11.92	2.99	3.99	0.82	8.3	1.00	.261	2.61	54	2.72	63	5.99	159
6	David Robertson D. Robertson	31.9	881	68	46	.596	1	2.93	1,176	0	0	179	894.1	674	291	315	81	365	25	358	38	3,690	57	11.83	3.67	3.22	0.82	9.9	1.16	.290	3.17	70	2.98	70	6.78	122.3
7	Brad Lidge B. Lidge	30.9	603	26	32	.448	1	3.54	799	0	0	225	603.1	492	237	257	57	287	34	368	41	2,589	46	11.92	4.28	2.78	0.85	11.1	1.29	.308	3.83	82	3.26	75	7.34	72.7
8	Greg Holland G. Holland	29.8	556	30	28	.517	0	3.14	677	0	0	220	547.2	417	191	211	43	241	7	355	20	2,271	50	11.13	3.96	2.81	0.71	10.6	1.20	.287	3.47	74	3.02	73	6.85	66.2
9	Carlos Marmol C. Marmol	29.5	519	23	35	.397	13	3.57	744	0	0	117	577.0	385	229	242	49	395	51	259	22	2,521	35	11.60	6.16	1.88	0.76	15.7	1.35	.262	3.77	85	3.95	94	6.01	15.6
10	Héctor Neris H. Neris	29.4	643	46	43	.517	0	3.47	775	0	0	107	627.1	509	242	272	83	243	36	274	16	2,632	38	11.12	3.49	3.19	1.19	9.2	1.20	.285	3.90	84	3.75	89	7.30	33.5
11	Raisel Iglesias R. Iglesias	29.3	600	42	55	.433	21	2.92	869	0	0	253	736.0	570	239	265	83	202	27	459	17	2,962	17	10.63	2.47	4.30	1.01	6.8	1.05	.273	3.24	69	3.19	76	6.97	82.7
12	Armando Benitez A. Benitez	29.1	762	40	47	.460	0	3.13	946	0	0	289	779.0	545	271	296	95	403	16	527	32	3,253	18	10.93	4.66	2.35	1.10	12.4	1.22	.251	3.42	72	3.86	88	6.30	48.8
13	Brad Boxberger B. Boxberger	28.7	506	31	38	.449	0	3.50	581	0	0	84	477.2	372	186	204	63	233	23	167	17	2,021	16	10.95	4.39	2.49	1.19	11.5	1.27	.276	3.84	87	4.03	100	7.01	-0.2
14	Jake Diekman J. Diekman	28.7	705	27	34	.443	0	3.91	764	0	0	19	602.1	483	262	312	53	358	47	141	21	2,662	44	11.42	5.35	2.13	0.79	13.4	1.40	.299	4.66	95	3.77	91	7.22	23.8
15	Randy Johnson R. Johnson	28.6	618	303	166	.646	603	3.29	4,875	100	37	2	4135.1	3,346	1,513	1,703	411	1,497	190	7	37	17,067	109	10.61	3.26	3.26	0.89	8.8	1.17	.291	3.71	75	3.18	73	7.28	554.3
16	Francisco Rodriguez F. Rodriguez	28.5	948	52	53	.495	0	2.86	1,142	0	0	437	976.0	738	310	336	98	389	17	677	42	4,011	68	10.53	3.59	2.94	0.90	9.7	1.15	.271	3.10	69	3.30	79	6.81	97
17	Octavio Dotel O. Dotel	28.4	758	59	50	.541	34	3.78	1,143	0	0	109	951.0	765	399	431	117	412	41	305	39	4,024	46	10.82	3.90	2.77	1.11	10.2	1.24	.280	4.08	86	3.69	84	7.24	73.6
18	Ugueth Urbina U. Urbina	27.9	583	44	49	.473	21	3.45	814	0	0	237	697.1	539	267	289	86	307	6	408	30	2,918	29	10.51	3.96	2.65	1.11	10.5	1.21	.266	3.73	78	3.69	85	6.96	51.2
19	Taylor Rogers T. Rogers	27.7	566	31	36	.463	0	3.34	626	0	0	83	541.1	482	201	233	57	165	36	164	22	2,256	12	10.41	2.74	3.79	0.95	7.3	1.20	.310	3.87	79	3.33	79	8.01	54.9
20	Jonathan Papelbon J. Papelbon	27.5	689	41	36	.532	3	2.44	808	0	0	368	725.2	572	197	226	57	185	34	585	18	2,938	14	10.02	2.29	4.37	0.71	6.3	1.04	.278	2.80	58	2.80	69	7.09	105.2
21	B.J. Ryan	27.5	560	21	28	.429	0	3.37	625	0	0	117	536.2	424	201	216	42	264	17	249	27	2,273	21	10.48	4.43	2.37	0.70	11.6	1.28	.288	3.62	76	3.32	73	7.11	71.3
22	Will Smith W. Smith	27.4	618	33	45	.423	17	3.85	748	0	0	113	652.1	570	279	313	84	238	17	237	26	2,729	30	10.32	3.28	3.14	1.16	8.7	1.24	.296	4.32	94	3.70	91	7.86	27
23	Adam Ottavino A. Ottavino	27.2	727	41	43	.488	3	3.48	862	0	0	46	744.2	628	288	308	72	330	50	168	32	3,167	66	10.42	3.99	2.61	0.87	10.4	1.29	.300	3.72	79	3.61	85	7.59	49.8
24	Andrew Miller A. Miller	27.1	612	55	55	.500	66	4.03	979	0	0	63	829.0	732	371	413	80	383	61	147	14	3,619	44	10.63	4.16	2.56	0.87	10.6	1.34	.308	4.48	95	3.63	87	7.95	49.8
25	Sergio Romo S. Romo	27.0	821	42	36	.538	5	3.21	789	0	0	137	722.2	579	258	275	85	179	27	301	21	2,919	22	9.83	2.23	4.41	1.06	6.1	1.05	.269	3.42	82	3.32	84	7.21	50.2