Luke Hudson has the highest WHIP in a game, with a WHIP of 33.00 versus the Cleveland Indians on August 13, 2006.

Interpreted as:

highest whip by a player in a single regular-season game

	NAME	WHIP	DATE	TM		OPP	DEC	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP
1	Luke Hudson L. Hudson	33.00	8/13/2006	KCR	@	CLE	L	1	270.00	1	0	0	0	0.1	8	10	11	1	3	0	0	0	13	0
2	Jhonathan Díaz J. Díaz	27.00	9/15/2023	LAA	vs	DET		0	189.00	0	0	0	0	0.1	7	7	7	0	2	0	0	0	10	0
3	Paolo Espino P. Espino	27.00	7/18/2023	WSH	@	CHC		0	216.00	1	0	0	0	0.1	7	8	8	0	2	0	0	0	10	0
4	Jimmy Yacabonis J. Yacabonis	27.00	7/20/2019	BAL	vs	BOS		0	189.00	0	0	0	0	0.1	8	7	7	1	1	0	0	0	10	2
5	Philip Humber P. Humber	27.00	4/20/2013	HOU	vs	CLE	L	1	216.00	0	0	0	0	0.1	8	8	8	1	1	0	0	0	10	0
6	Philip Humber P. Humber	27.00	9/4/2012	CWS	vs	MIN		0	216.00	0	0	0	0	0.1	7	8	8	1	2	0	0	0	10	0
7	Madison Bumgarner M. Bumgarner	27.00	6/21/2011	SFG	vs	MIN	L	1	216.00	1	0	0	0	0.1	9	8	8	0	0	0	0	0	10	0
8	Jason Miller J. Miller	27.00	6/4/2007	MIN	@	LAA		0	216.00	0	0	0	0	0.1	7	8	8	2	2	0	0	1	10	0
9	Mark Redman M. Redman	27.00	9/23/2006	KCR	vs	DET	L	1	243.00	0	0	0	0	0.1	7	9	9	1	2	0	0	0	10	0
10	Saul Rivera S. Rivera	27.00	7/5/2006	WSH	vs	FLA		0	189.00	0	0	0	0	0.1	8	7	8	0	1	0	0	1	11	0
11	Jose Mesa J. Mesa	27.00	5/28/2000	SEA	@	TBD	L	0	243.00	0	0	0	0	0.1	7	9	9	1	2	0	0	0	10	0
12	Dave Tomlin D. Tomlin	27.00	8/10/1978	CIN	@	SDP		0	162.00	0	0	0	0	0.1	7	6	6	0	2	0	0	0	10	0
13	Lou Brissie L. Brissie	27.00	6/18/1950	PHA	@	CLE	L	1	243.00	0	0	0	0	0.1	3	9	9	0	6	0	0	0	10	0
14	Dave Keefe D. Keefe	27.00	9/10/1921	PHA	vs	NYY		0	135.00	0	0	0	0	0.1	6	5	8	0	3	0	0		11	0
15	Roansy Contreras R. Contreras	24.00	6/7/2023	PIT	vs	OAK	L	1	189.00	1	0	0	0	0.1	6	7	7	0	2	0	0	0	9	0
16	Alek Manoah A. Manoah	24.00	6/5/2023	TOR	vs	HOU	L	1	162.00	0	0	0	0	0.1	7	6	6	1	1	0	0	0	9	0
17	Cody Bolton C. Bolton	24.00	5/29/2023	PIT	@	SFG		0	216.00	0	0	0	0	0.1	6	8	8	1	2	0	0	0	9	0
18	Spenser Watkins S. Watkins	24.00	9/12/2021	BAL	vs	TOR		0	189.00	0	0	0	0	0.1	7	7	7	2	1	0	0	0	8	0
19	Taijuan Walker T. Walker	24.00	7/18/2021	NYM	@	PIT		1	135.00	0	0	0	0	0.1	4	5	6	0	4	0	0	0	9	0
20	Matt Shoemaker M. Shoemaker	24.00	6/4/2021	MIN	@	KCR	L	1	216.00	1	0	0	0	0.1	6	8	9	1	2	0	0	0	10	0
21	Wade Miley W. Miley	24.00	9/10/2019	HOU	vs	OAK	L	1	189.00	0	0	0	0	0.1	7	7	7	0	1	0	0	0	9	0
22	Taylor Williams T. Williams	24.00	6/4/2019	MIL	vs	MIA		0	216.00	1	0	0	0	0.1	6	8	8	0	2	0	0	1	9	0
23	Felix Pena F. Pena	24.00	7/29/2018	LAA	vs	SEA	L	1	189.00	1	0	0	0	0.1	6	7	7	0	2	0	0	0	9	1
24	Trevor Hildenberger T. Hildenberger	24.00	6/30/2018	MIN	@	CHC	L	0	135.00	0	0	0	0	0.1	4	5	5	0	4	0	0	2	9	0
25	Carlos Rodón C. Rodón	24.00	4/18/2016	CWS	vs	LAA	L	1	135.00	1	0	0	0	0.1	6	5	5	0	2	0	0	0	9	0