Billy Wagner has the most career saves for the Astros, with 225 saves.

Interpreted as:

houston astros pitchers with most regular-season saves

	NAME	SV	G	W	L	W%	GS	ERA	SO	CG	SHO	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Billy Wagner B. Wagner	225	464	26	29	.473	0	2.53	694	0	0	504.1	333	142	149	48	191	18	379	15	2,027	28	12.38	3.41	3.63	0.86	34.2	9.4	1.04	.265	2.66	59	2.80	66	5.94	83.4
2	Dave Smith D. Smith	199	563	53	47	.530	1	2.53	529	0	0	762.0	646	214	254	28	260	12	400	57	3,145	27	6.25	3.07	2.03	0.33	16.8	8.3	1.19	.267	3.00	74	2.90	84	7.63	47.3
3	Brad Lidge B. Lidge	123	378	23	20	.535	1	3.30	561	0	0	401.0	310	147	160	38	170	26	206	22	1,684	32	12.59	3.82	3.30	0.85	33.3	10.1	1.20	.306	3.59	76	2.98	67	6.96	64.4
4	Ryan Pressly R. Pressly	110	342	18	20	.474	0	2.81	411	0	0	333.0	260	104	121	29	82	5	183	2	1,330	19	11.11	2.22	5.01	0.78	30.9	6.2	1.03	.288	3.27	68	2.63	63	7.03	58.9
5	Fred Gladding F. Gladding	76	233	22	23	.489	0	3.68	132	0	0	264.0	282	108	126	11	92	14	163	28	1,152	16	4.50	3.14	1.43	0.38	11.5	8.0	1.42	.300	4.30	104	3.25	95	9.61	5.2
6	Joe Sambito J. Sambito	72	353	33	32	.508	5	2.42	421	1	1	536.0	441	144	168	35	155	8	229	26	2,157	11	7.07	2.60	2.72	0.59	19.5	7.2	1.11	.264	2.82	71	2.87	83	7.40	35
7	Jose Valverde J. Valverde	69	126	10	5	.667	0	2.93	139	0	0	126.0	102	41	43	15	44	4	116	7	522	4	9.93	3.14	3.16	1.07	26.6	8.4	1.16	.272	3.07	70	3.59	83	7.29	10.1
8	Josh Hader J. Hader	62	119	14	10	.583	0	3.06	181	0	0	123.2	72	42	49	20	41	3	103	1	484	6	13.17	2.98	4.41	1.46	37.4	8.5	0.91	.218	3.57	77	3.39	83	5.24	9.6
9	Doug Jones D. Jones	62	151	15	18	.455	0	3.02	159	0	0	197.0	198	66	75	12	38	10	130	11	821	5	7.26	1.74	4.18	0.55	19.4	4.6	1.20	.309	3.43	82	2.77	77	9.05	17.6
10	Ken Giles K. Giles	61	166	3	10	.231	0	3.57	216	0	0	159.0	140	63	65	14	49	3	103	1	662	18	12.23	2.77	4.41	0.79	32.6	7.4	1.19	.332	3.68	87	2.56	60	7.92	30.1
11	Roberto Osuna R. Osuna	51	93	6	5	.545	0	2.45	95	0	0	92.0	65	25	26	9	15	4	76	0	356	3	9.29	1.47	6.33	0.88	26.7	4.2	0.87	.240	2.54	55	3.02	68	6.36	14.5
12	Ken Forsch K. Forsch	50	421	78	81	.491	153	3.18	815	36	9	1493.2	1,439	528	587	96	428	26	171	58	6,213	36	4.91	2.58	1.90	0.58	13.1	6.9	1.25	.277	3.54	92	3.25	94	8.67	30.3
13	Luke Gregerson L. Gregerson	47	188	13	9	.591	0	3.66	196	0	0	179.2	148	73	78	23	48	4	91	8	732	12	9.82	2.40	4.08	1.15	26.8	6.6	1.09	.271	3.91	90	3.49	83	7.41	13.8
14	Frank DiPino F. DiPino	43	201	13	25	.342	6	3.65	233	0	0	291.1	254	118	135	18	126	6	119	24	1,226	10	7.20	3.89	1.85	0.56	19.0	10.3	1.30	.280	4.17	106	3.29	96	7.85	4
15	Octavio Dotel O. Dotel	42	302	22	24	.478	20	3.25	552	0	0	449.0	344	162	176	51	181	17	109	13	1,869	17	11.06	3.63	3.05	1.02	29.5	9.7	1.17	.274	3.53	71	3.38	75	6.90	53.9
16	Todd Jones T. Jones	39	194	18	12	.600	0	3.27	228	0	0	267.0	230	97	105	20	125	13	105	29	1,143	10	7.69	4.21	1.82	0.67	19.9	10.9	1.33	.277	3.54	83	3.92	98	7.75	2.6
17	Hal Woodeshick H. Woodeshick	36	174	21	38	.356	26	3.16	256	2	1	364.0	336	128	158	12	146	16	103	23	1,576	32	6.33	3.61	1.75	0.30	16.2	9.3	1.32	.283	3.91	90	2.92	87	8.31	17.6
18	Chad Qualls C. Qualls	29	380	27	22	.551	0	3.51	307	0	0	384.2	367	150	159	41	98	23	110	17	1,586	7	7.18	2.29	3.13	0.96	19.4	6.2	1.21	.292	3.72	84	3.85	89	8.59	19.5
19	John Hudek J. Hudek	29	116	5	7	.417	0	4.42	118	0	0	116.0	93	57	58	18	61	4	75	6	495	7	9.16	4.73	1.93	1.40	23.8	12.3	1.33	.255	4.50	112	4.78	119	7.22	-10.5
20	Frank LaCorte F. LaCorte	26	196	18	18	.500	3	4.03	229	0	0	281.2	229	126	139	21	148	2	117	17	1,205	18	7.32	4.73	1.55	0.67	19.0	12.3	1.34	.258	4.44	119	3.65	107	7.32	-8.8
21	Claude Raymond C. Raymond	26	154	19	18	.514	7	2.98	225	2	0	299.0	267	99	114	24	70	14	82	13	1,218	15	6.77	2.11	3.21	0.72	18.5	5.7	1.13	.275	3.43	87	2.94	89	8.04	11.9
22	Xavier Hernandez X. Hernandez	25	273	22	19	.537	7	3.40	354	0	0	407.2	351	154	175	36	152	10	99	27	1,717	26	7.82	3.36	2.33	0.79	20.6	8.9	1.23	.270	3.86	92	3.51	96	7.75	6.3
23	Brandon Lyon B. Lyon	24	131	9	11	.450	0	4.03	95	0	0	127.1	132	57	58	9	47	5	52	15	558	9	6.71	3.32	2.02	0.64	17.0	8.4	1.41	.306	4.10	103	3.72	94	9.33	3.8
24	Matt Lindstrom M. Lindstrom	23	58	2	5	.286	0	4.39	43	0	0	53.1	68	26	26	5	20	0	41	1	244	8	7.26	3.38	2.15	0.84	17.6	8.2	1.65	.358	4.39	110	3.80	94	11.48	1.4
25	Dan Wheeler D. Wheeler	23	205	6	12	.333	0	3.02	202	0	0	208.2	168	70	72	21	59	8	74	12	843	1	8.71	2.54	3.42	0.91	24.0	7.0	1.09	.266	3.11	69	3.44	77	7.25	23.3