Kyle Lohse had a record of 55-35 with an ERA of 3.90 and 504 strikeouts in 137 appearances for the Cardinals in his career.
| NAME | SEASON | TM | G | W | L | W% | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | K. Lohse | 2008 |  STL | 33 | 15 | 6 | .714 | 33 | 3.78 | 119 | 0 | 0 | 0 | 200.0 | 211 | 84 | 88 | 18 | 49 | 3 | 0 | 3 | 839 | 5 | 5.36 | 2.21 | 2.43 | 0.81 | 14.2 | 5.8 | 1.30 | .297 | 3.96 | 91 | 3.88 | 92 | 9.50 | 7.6 |
| 2 | | K. Lohse | 2009 | STL | 23 | 6 | 10 | .375 | 22 | 4.74 | 77 | 1 | 1 | 0 | 117.2 | 125 | 62 | 69 | 16 | 36 | 3 | 0 | 2 | 512 | 3 | 5.89 | 2.75 | 2.14 | 1.22 | 15.0 | 7.0 | 1.37 | .287 | 5.28 | 117 | 4.54 | 111 | 9.56 | -6.1 |
| 3 | | K. Lohse | 2010 | STL | 18 | 4 | 8 | .333 | 18 | 6.55 | 54 | 0 | 0 | 0 | 92.0 | 129 | 67 | 75 | 9 | 35 | 3 | 0 | 2 | 431 | 1 | 5.28 | 3.42 | 1.54 | 0.88 | 12.5 | 8.1 | 1.78 | .364 | 7.34 | 168 | 4.41 | 113 | 12.62 | -5.3 |
| 4 | | K. Lohse | 2011 | STL | 30 | 14 | 8 | .636 | 30 | 3.39 | 111 | 1 | 1 | 0 | 188.1 | 178 | 71 | 80 | 16 | 42 | 3 | 0 | 1 | 775 | 1 | 5.30 | 2.01 | 2.64 | 0.76 | 14.3 | 5.4 | 1.17 | .269 | 3.82 | 92 | 3.66 | 98 | 8.51 | 1.2 |
| 5 | | K. Lohse | 2012 | STL | 33 | 16 | 3 | .842 | 33 | 2.86 | 143 | 0 | 0 | 0 | 211.0 | 192 | 67 | 74 | 19 | 38 | 4 | 0 | 1 | 864 | 1 | 6.10 | 1.62 | 3.76 | 0.81 | 16.6 | 4.4 | 1.09 | .262 | 3.16 | 74 | 3.50 | 91 | 8.19 | 8.5 |
| Total | 137 | 55 | 35 | .611 | 136 | 3.90 | 504 | 2 | 2 | 0 | 809.0 | 835 | 351 | 386 | 78 | 200 | 16 | 0 | 9 | 3,421 | 11 | 5.61 | 2.22 | 2.52 | 0.87 | 14.7 | 5.8 | 1.28 | .289 | 4.29 | 99 | 3.89 | 98 | 9.29 | 6 |
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