largest margin of victory in an mlb game this year

The Cincinnati Reds have the highest run differential by a team in a game this season, with a differential of 22 runs against the Orioles on April 20.

Interpreted as:

largest margin of victory in an MLB regular-season game this year

	TEAM	DIFF	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Reds	22	4/20/2025	CIN	@	BAL	W 24-2	51	24	25	4	1	3	23	11	2	6	1	0	64	40	8	0	0	0	1	.490	.594	.784	1.378
2	Cubs	16	4/12/2025	CHC	@	LAD	W 16-0	47	16	21	5	0	4	16	4	1	4	1	0	53	38	9	0	1	0	0	.447	.491	.809	1.299
3	Rays	15	4/14/2025	TBR	vs	BOS	W 16-1	40	16	16	2	0	4	16	4	0	9	1	0	44	30	6	0	0	0	1	.400	.455	.750	1.205
4	Brewers	15	4/9/2025	MIL	@	COL	W 17-2	40	17	13	2	0	3	15	5	0	6	3	0	46	24	5	0	1	0	1	.325	.391	.600	.991
5	Cubs	15	3/31/2025	CHC	@	ATH	W 18-3	48	18	21	6	1	4	18	10	1	7	0	0	60	41	11	0	1	0	0	.438	.533	.854	1.388
6	Mets	14	4/28/2025	NYM	@	WSH	W 19-5	47	19	21	3	1	4	19	6	2	9	0	0	56	38	8	0	1	0	0	.447	.518	.809	1.326
7	Mariners	14	4/26/2025	SEA	vs	MIA	W 14-0	37	14	15	3	0	4	14	7	1	6	0	0	46	30	7	0	1	0	0	.405	.500	.811	1.311
8	Dodgers	13	4/29/2025	LAD	vs	MIA	W 15-2	40	15	18	6	0	2	15	8	0	5	4	0	49	30	8	0	1	0	1	.450	.531	.750	1.281
9	Rangers	13	4/29/2025	TEX	vs	ATH	W 15-2	39	15	18	4	0	0	15	9	1	8	1	0	49	22	4	0	0	0	2	.462	.571	.564	1.136
10	Brewers	13	4/20/2025	MIL	vs	ATH	W 14-1	37	14	17	2	0	1	9	7	1	3	9	1	46	22	3	0	1	0	1	.459	.543	.595	1.138
11	Tigers	12	5/4/2025	DET	@	LAA	W 13-1	41	13	16	2	0	3	13	4	3	8	0	0	48	27	5	0	0	0	2	.390	.479	.659	1.138
12	Mariners	12	5/2/2025	SEA	@	TEX	W 13-1	43	13	17	4	0	3	13	3	1	3	0	0	48	30	7	0	1	0	1	.395	.438	.698	1.135
13	Yankees	12	4/29/2025	NYY	@	BAL	W 15-3	48	15	19	4	0	6	14	4	2	9	0	0	54	41	10	0	0	0	0	.396	.463	.854	1.317
14	Astros	11	4/11/2025	HOU	vs	LAA	W 14-3	38	14	17	1	0	3	13	8	0	3	3	0	48	27	4	0	2	0	0	.447	.521	.711	1.231
15	Red Sox	11	4/6/2025	BOS	vs	STL	W 18-7	46	18	21	8	0	1	17	4	0	5	1	0	50	32	9	0	0	0	0	.457	.500	.696	1.196
16	Reds	11	3/31/2025	CIN	vs	TEX	W 14-3	38	14	14	2	0	3	14	4	2	8	2	0	44	25	5	0	0	0	1	.368	.455	.658	1.112
17	Yankees	11	3/29/2025	NYY	vs	MIL	W 20-9	40	20	16	2	0	9	20	8	2	5	0	0	51	45	11	0	1	0	0	.400	.510	1.125	1.635
18	Cubs	10	5/2/2025	CHC	@	MIL	W 10-0	39	10	12	1	0	3	10	4	0	8	0	0	43	22	4	0	0	0	0	.308	.372	.564	.936
19	Twins	10	4/28/2025	MIN	@	CLE	W 11-1	43	11	17	3	0	2	11	3	0	5	0	0	46	26	5	0	0	0	0	.395	.435	.605	1.039
20	Red Sox	10	4/27/2025	BOS	@	CLE	W 13-3	40	13	15	3	0	3	11	5	0	7	2	1	47	27	6	0	2	0	0	.375	.426	.675	1.101
21	White Sox	10	4/11/2025	CWS	vs	BOS	W 11-1	36	11	12	4	0	0	11	4	0	9	4	0	41	16	4	0	1	0	0	.333	.390	.444	.835
22	Angels	10	4/10/2025	LAA	@	TBR	W 11-1	40	11	14	2	0	6	11	1	0	5	0	0	41	34	8	0	0	0	1	.350	.366	.850	1.216
23	Braves	10	4/4/2025	ATL	vs	MIA	W 10-0	40	10	16	2	0	2	10	3	1	9	0	0	44	24	4	0	0	0	0	.400	.455	.600	1.055
24	Royals	10	3/31/2025	KCR	@	MIL	W 11-1	41	11	14	2	0	2	11	5	2	7	2	0	48	22	4	0	0	0	0	.341	.438	.537	.974
25	Orioles	10	3/27/2025	BAL	@	TOR	W 12-2	39	12	14	1	0	6	12	5	1	8	0	1	45	33	7	0	0	0	0	.359	.444	.846	1.291