largest point differential in a baseball game by the twins franchise ever

The Minnesota Twins have the highest run differential by a team in a game, with a differential of 21 runs against the Cleveland Indians on June 4, 2002.

Interpreted as:

largest point differential in a baseball regular-season game by the twins franchise ever

	TEAM	DIFF	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Twins	21	6/4/2002	MIN	vs	CLE	W 23-2	50	23	25	6	1	3	22	7	0	4	0	0	57	42	10	0	0	1	0	.500	.561	.840	1.401
2	Twins	19	5/21/2009	MIN	@	CWS	W 20-1	46	20	20	4	0	4	18	5	1	5	0	0	54	36	8	1	1	1	0	.435	.491	.783	1.273
3	Twins	19	5/20/1994	MIN	vs	BOS	W 21-2	44	21	22	5	0	1	21	7	1	6	1	0	54	30	6	0	2	0	0	.500	.556	.682	1.237
4	Twins	18	7/26/2010	MIN	@	KCR	W 19-1	44	19	20	7	2	2	19	6	1	12	0	0	52	37	11	0	1	0	1	.455	.519	.841	1.360
5	Twins	17	9/2/2017	MIN	vs	KCR	W 17-0	36	17	14	2	2	3	17	9	0	4	0	0	46	29	7	0	1	0	1	.389	.500	.806	1.306
6	Twins	17	9/5/1976	MIN	vs	CWS	W 18-1	43	18	22	4	1	2	17	7	0	0	2	1	52	34	7	1	1	0	0	.512	.569	.791	1.359
7	Twins	16	9/12/2017	MIN	vs	SDP	W 16-0	42	16	18	2	1	7	16	1	1	6	0	0	44	43	10	0	0	0	0	.429	.455	1.024	1.478
8	Twins	16	5/25/1990	MIN	vs	BOS	W 16-0	42	16	19	4	3	0	14	2	0	2	0	0	46	29	7	0	2	0	3	.452	.457	.690	1.147
9	Twins	16	5/20/1989	MIN	@	TEX	W 19-3	46	19	20	2	0	4	19	8	0	6	1	0	55	34	6	0	1	0	0	.435	.509	.739	1.248
10	Senators	16	5/1/1936	WSH	vs	SLA	W 17-1	41	17	18	2	2	0	15	6	0	2	0	2	48	24	4	1				.439	.511	.585	1.096
11	Senators	16	8/5/1929	WSH	vs	DET	W 21-5	41	21	21	1	2	1	16	6	0	1	4	0	51	29	4	4				.512	.574	.707	1.282
12	Twins	15	5/16/2003	MIN	vs	CWS	W 18-3	43	18	20	4	0	4	18	4	0	4	0	0	48	36	8	1	0	0	0	.465	.511	.837	1.348
13	Twins	15	5/24/1992	MIN	@	DET	W 15-0	43	15	18	2	0	1	14	7	1	7	0	0	52	23	3	0	1	0	0	.419	.500	.535	1.035
14	Twins	15	7/10/1977	MIN	vs	SEA	W 15-0	41	15	16	2	2	1	13	9	0	6	2	0	50	25	5	0	0	1	0	.390	.500	.610	1.110
15	Twins	15	9/10/1976	MIN	vs	KCR	W 18-3	38	18	18	3	1	1	16	14	0	2	1	0	55	26	5	1	2	1	1	.474	.593	.684	1.277
16	Twins	15	7/24/1976	MIN	@	CWS	W 17-2	42	17	17	3	1	3	15	11	0	6	0	1	56	31	7	1	2	0	0	.405	.509	.738	1.247
17	Senators	15	7/10/1926	WSH	vs	SLA	W 19-4	40	19	19	4	2	0	16	7	0	2	3	1	48	27	6	1				.475	.553	.675	1.228
18	Senators	15	8/22/1925	WSH	@	DET	W 20-5	44	20	19	5	1	3	18	10	0	1	0	0	55	35	9	1				.432	.537	.795	1.332
19	Senators	15	9/29/1915	WSH	vs	PHA	W 20-5	43	20	23	4	2	0		4	1	3	7		52	31	6	4				.535	.583	.721	1.304
20	Twins	14	9/4/2023	MIN	@	CLE	W 20-6	46	20	20	2	0	6	20	6	0	4	0	0	53	40	8	0	1	0	0	.435	.491	.870	1.360
21	Twins	14	5/18/2019	MIN	@	SEA	W 18-4	46	18	19	5	0	6	18	6	0	5	0	0	53	42	11	0	1	0	0	.413	.472	.913	1.385
22	Twins	14	8/22/2014	MIN	vs	DET	W 20-6	46	20	20	4	1	4	18	9	0	8	1	0	55	38	9	0	0	0	0	.435	.527	.826	1.353
23	Twins	14	6/19/2003	MIN	@	KCR	W 16-2	50	16	23	5	0	3	16	4	0	3	1	0	54	37	8	0	0	0	0	.460	.500	.740	1.240
24	Twins	14	6/4/1994	MIN	@	DET	W 21-7	49	21	24	3	0	4	20	5	1	8	0	0	57	39	7	1	1	0	1	.490	.536	.796	1.332
25	Twins	14	4/11/1989	MIN	@	DET	W 14-0	41	14	19	6	0	2	14	8	0	6	1	2	50	31	8	1	0	0	0	.463	.551	.756	1.307