The Minnesota Twins have the highest run differential by a team in a game, with a differential of 21 runs against the Cleveland Indians on June 4, 2002.
Interpreted as:
largest point differential in a baseball regular-season game by the twins franchise ever| TEAM | DIFF | DATE | TM | OPP | RESULT | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Twins | 21 | 6/4/2002 | vs | W 23-2 | 50 | 23 | 25 | 6 | 1 | 3 | 22 | 7 | 0 | 4 | 0 | 0 | 57 | 42 | 10 | 0 | 0 | 1 | 0 | .500 | .561 | .840 | 1.401 | ||
| 2 | | Twins | 19 | 5/21/2009 | @ | W 20-1 | 46 | 20 | 20 | 4 | 0 | 4 | 18 | 5 | 1 | 5 | 0 | 0 | 54 | 36 | 8 | 1 | 1 | 1 | 0 | .435 | .491 | .783 | 1.273 | ||
| 3 | | Twins | 19 | 5/20/1994 | vs | W 21-2 | 44 | 21 | 22 | 5 | 0 | 1 | 21 | 7 | 1 | 6 | 1 | 0 | 54 | 30 | 6 | 0 | 2 | 0 | 0 | .500 | .556 | .682 | 1.237 | ||
| 4 | | Twins | 18 | 7/26/2010 | @ | W 19-1 | 44 | 19 | 20 | 7 | 2 | 2 | 19 | 6 | 1 | 12 | 0 | 0 | 52 | 37 | 11 | 0 | 1 | 0 | 1 | .455 | .519 | .841 | 1.360 | ||
| 5 |  | Twins | 17 | 9/2/2017 | vs | W 17-0 | 36 | 17 | 14 | 2 | 2 | 3 | 17 | 9 | 0 | 4 | 0 | 0 | 46 | 29 | 7 | 0 | 1 | 0 | 1 | .389 | .500 | .806 | 1.306 | ||
| 6 | | Twins | 17 | 9/5/1976 | vs | W 18-1 | 43 | 18 | 22 | 4 | 1 | 2 | 17 | 7 | 0 | 0 | 2 | 1 | 52 | 34 | 7 | 1 | 1 | 0 | 0 | .512 | .569 | .791 | 1.359 | ||
| 7 | | Twins | 16 | 9/12/2017 | vs | W 16-0 | 42 | 16 | 18 | 2 | 1 | 7 | 16 | 1 | 1 | 6 | 0 | 0 | 44 | 43 | 10 | 0 | 0 | 0 | 0 | .429 | .455 | 1.024 | 1.478 | ||
| 8 | | Twins | 16 | 5/25/1990 | vs | W 16-0 | 42 | 16 | 19 | 4 | 3 | 0 | 14 | 2 | 0 | 2 | 0 | 0 | 46 | 29 | 7 | 0 | 2 | 0 | 3 | .452 | .457 | .690 | 1.147 | ||
| 9 | | Twins | 16 | 5/20/1989 | @ | W 19-3 | 46 | 19 | 20 | 2 | 0 | 4 | 19 | 8 | 0 | 6 | 1 | 0 | 55 | 34 | 6 | 0 | 1 | 0 | 0 | .435 | .509 | .739 | 1.248 | ||
| 10 |  | Senators | 16 | 5/1/1936 | vs | W 17-1 | 41 | 17 | 18 | 2 | 2 | 0 | 15 | 6 | 0 | 2 | 0 | 2 | 48 | 24 | 4 | 1 | .439 | .511 | .585 | 1.096 | |||||
| 11 | | Senators | 16 | 8/5/1929 | vs | W 21-5 | 41 | 21 | 21 | 1 | 2 | 1 | 16 | 6 | 0 | 1 | 4 | 0 | 51 | 29 | 4 | 4 | .512 | .574 | .707 | 1.282 | |||||
| 12 | | Twins | 15 | 5/16/2003 | vs | W 18-3 | 43 | 18 | 20 | 4 | 0 | 4 | 18 | 4 | 0 | 4 | 0 | 0 | 48 | 36 | 8 | 1 | 0 | 0 | 0 | .465 | .511 | .837 | 1.348 | ||
| 13 | | Twins | 15 | 5/24/1992 | @ | W 15-0 | 43 | 15 | 18 | 2 | 0 | 1 | 14 | 7 | 1 | 7 | 0 | 0 | 52 | 23 | 3 | 0 | 1 | 0 | 0 | .419 | .500 | .535 | 1.035 | ||
| 14 | | Twins | 15 | 7/10/1977 | vs | W 15-0 | 41 | 15 | 16 | 2 | 2 | 1 | 13 | 9 | 0 | 6 | 2 | 0 | 50 | 25 | 5 | 0 | 0 | 1 | 0 | .390 | .500 | .610 | 1.110 | ||
| 15 | | Twins | 15 | 9/10/1976 | vs | W 18-3 | 38 | 18 | 18 | 3 | 1 | 1 | 16 | 14 | 0 | 2 | 1 | 0 | 55 | 26 | 5 | 1 | 2 | 1 | 1 | .474 | .593 | .684 | 1.277 | ||
| 16 | | Twins | 15 | 7/24/1976 | @ | W 17-2 | 42 | 17 | 17 | 3 | 1 | 3 | 15 | 11 | 0 | 6 | 0 | 1 | 56 | 31 | 7 | 1 | 2 | 0 | 0 | .405 | .509 | .738 | 1.247 | ||
| 17 | | Senators | 15 | 7/10/1926 | vs | W 19-4 | 40 | 19 | 19 | 4 | 2 | 0 | 16 | 7 | 0 | 2 | 3 | 1 | 48 | 27 | 6 | 1 | .475 | .553 | .675 | 1.228 | |||||
| 18 | | Senators | 15 | 8/22/1925 | @ | W 20-5 | 44 | 20 | 19 | 5 | 1 | 3 | 18 | 10 | 0 | 1 | 0 | 0 | 55 | 35 | 9 | 1 | .432 | .537 | .795 | 1.332 | |||||
| 19 | | Senators | 15 | 9/29/1915 | vs | W 20-5 | 43 | 20 | 23 | 4 | 2 | 0 | 4 | 1 | 3 | 7 | 52 | 31 | 6 | 4 | .535 | .583 | .721 | 1.304 | |||||||
| 20 | | Twins | 14 | 9/4/2023 | @ | W 20-6 | 46 | 20 | 20 | 2 | 0 | 6 | 20 | 6 | 0 | 4 | 0 | 0 | 53 | 40 | 8 | 0 | 1 | 0 | 0 | .435 | .491 | .870 | 1.360 | ||
| 21 | | Twins | 14 | 5/18/2019 | @ | W 18-4 | 46 | 18 | 19 | 5 | 0 | 6 | 18 | 6 | 0 | 5 | 0 | 0 | 53 | 42 | 11 | 0 | 1 | 0 | 0 | .413 | .472 | .913 | 1.385 | ||
| 22 | | Twins | 14 | 8/22/2014 | vs | W 20-6 | 46 | 20 | 20 | 4 | 1 | 4 | 18 | 9 | 0 | 8 | 1 | 0 | 55 | 38 | 9 | 0 | 0 | 0 | 0 | .435 | .527 | .826 | 1.353 | ||
| 23 | | Twins | 14 | 6/19/2003 | @ | W 16-2 | 50 | 16 | 23 | 5 | 0 | 3 | 16 | 4 | 0 | 3 | 1 | 0 | 54 | 37 | 8 | 0 | 0 | 0 | 0 | .460 | .500 | .740 | 1.240 | ||
| 24 | | Twins | 14 | 6/4/1994 | @ | W 21-7 | 49 | 21 | 24 | 3 | 0 | 4 | 20 | 5 | 1 | 8 | 0 | 0 | 57 | 39 | 7 | 1 | 1 | 0 | 1 | .490 | .536 | .796 | 1.332 | ||
| 25 | | Twins | 14 | 4/11/1989 | @ | W 14-0 | 41 | 14 | 19 | 6 | 0 | 2 | 14 | 8 | 0 | 6 | 1 | 2 | 50 | 31 | 8 | 1 | 0 | 0 | 0 | .463 | .551 | .756 | 1.307 | ||
MIN
CLE
CWS
BOS
KCR
MIN
CWS
SDP
TEX
WSH
SLA
SEA
PHASome of the information used here was obtained free of charge from Retrosheet.
More Twins Stats
Team Batting Leaders 
HR
35
Buxton
RBI
83
Buxton
AVG
.267
Correa
Team Pitching Leaders 
W
13
Ryan
K
194
Ryan
ERA
3.42
Ryan
Team Rankings
HR
191
11th
R
678
23rd
SO
1,372
15th
ERA
4.55
24th
BAL
MLB 2025 Batting Leaders
MLB 2025 Pitching Leaders
MLB Fantasy 2025
MLB 2025 Betting
MLB 2025 Standings
| NL East | W | L | PCT | GB |
|---|---|---|---|---|
 Phillies - y | 96 | 66 | .593 | |
83 | 79 | .512 | 13.0 | |
79 | 83 | .488 | 17.0 | |
76 | 86 | .469 | 20.0 | |
66 | 96 | .407 | 30.0 | |
| NL Central | W | L | PCT | GB |
 Brewers - y | 97 | 65 | .599 | |
 Cubs - w | 92 | 70 | .568 | 5.0 |
 Reds - w | 83 | 79 | .512 | 14.0 |
78 | 84 | .481 | 19.0 | |
71 | 91 | .438 | 26.0 | |
| NL West | W | L | PCT | GB |
 Dodgers - y | 93 | 69 | .574 | |
 Padres - w | 90 | 72 | .556 | 3.0 |
81 | 81 | .500 | 12.0 | |
80 | 82 | .494 | 13.0 | |
43 | 119 | .265 | 50.0 |
Mets
Marlins
Braves
Nationals
Cardinals
Pirates
Giants
Diamondbacks
Rockies| AL East | W | L | PCT | GB |
|---|---|---|---|---|
 Blue Jays - y | 94 | 68 | .580 | |
 Yankees - w | 94 | 68 | .580 | |
 Red Sox - w | 89 | 73 | .549 | 5.0 |
77 | 85 | .475 | 17.0 | |
75 | 87 | .463 | 19.0 | |
| AL Central | W | L | PCT | GB |
 Guardians - y | 88 | 74 | .543 | |
 Tigers - w | 87 | 75 | .537 | 1.0 |
82 | 80 | .506 | 6.0 | |
70 | 92 | .432 | 18.0 | |
60 | 102 | .370 | 28.0 | |
| AL West | W | L | PCT | GB |
 Mariners - y | 90 | 72 | .556 | |
87 | 75 | .537 | 3.0 | |
81 | 81 | .500 | 9.0 | |
76 | 86 | .469 | 14.0 | |
72 | 90 | .444 | 18.0 |
Rays
Astros
Rangers
Athletics
Angels
