Between the 2000 and 2009 seasons, Tim Lincecum had the lowest ERA when starting 50+ games, with an ERA of 2.90.

Interpreted as:

lowest era by a player in 2000s min 50 starts

	NAME	ERA	GS	G	W	L	W%	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Tim Lincecum T. Lincecum	2.90	89	90	40	17	.702	676	6	3	0	598.2	472	193	211	33	217	14	0	8	2,451	38	10.16	3.26	3.12	0.50	27.6	8.9	1.15	.291	3.17	68	2.75	65	7.10	99.7
2	Pedro Martinez P. Martinez	3.01	227	227	112	50	.691	1,620	18	6	0	1468.0	1,171	491	530	132	350	86	0	10	5,917	24	9.93	2.15	4.63	0.81	27.4	5.9	1.04	.279	3.25	68	2.91	67	7.18	241.6
3	Johan Santana J. Santana	3.12	234	310	122	60	.670	1,733	9	6	1	1709.2	1,430	592	641	187	473	34	23	10	6,946	65	9.12	2.49	3.66	0.98	24.9	6.8	1.11	.275	3.37	70	3.37	78	7.53	181.5
4	Adam Wainwright A. Wainwright	3.17	86	149	46	24	.657	511	3	0	3	644.0	616	227	248	49	193	19	11	8	2,714	19	7.14	2.70	2.65	0.68	18.8	7.1	1.26	.292	3.47	76	3.53	83	8.61	52.5
5	Jair Jurrjens J. Jurrjens	3.21	72	72	30	21	.588	304	0	0	0	434.0	398	155	174	30	156	8	0	10	1,819	8	6.30	3.24	1.95	0.62	16.7	8.6	1.28	.279	3.61	76	3.74	88	8.25	25.2
6	Roy Oswalt R. Oswalt	3.23	271	283	137	70	.662	1,473	18	6	0	1803.1	1,756	647	695	154	412	66	5	30	7,455	21	7.35	2.06	3.58	0.77	19.8	5.5	1.20	.299	3.47	75	3.34	76	8.76	208.1
7	Jake Peavy J. Peavy	3.26	215	215	95	68	.583	1,366	7	3	0	1362.2	1,169	494	525	136	441	45	0	31	5,626	26	9.02	2.91	3.10	0.90	24.3	7.8	1.18	.284	3.47	82	3.45	82	7.72	115.8
8	Brandon Webb B. Webb	3.27	198	199	87	62	.584	1,065	15	8	0	1319.2	1,200	479	557	92	435	50	1	34	5,515	56	7.26	2.97	2.45	0.63	19.3	7.9	1.24	.286	3.80	72	3.49	78	8.18	146.6
9	John Smoltz J. Smoltz	3.28	125	367	56	42	.571	986	6	2	154	1058.2	982	386	405	93	236	19	204	29	4,324	26	8.38	2.01	4.18	0.79	22.8	5.5	1.15	.297	3.44	76	3.09	71	8.35	147.5
10	Kevin Brown K. Brown	3.30	129	137	54	36	.600	696	6	1	0	825.2	766	303	342	68	218	31	0	7	3,417	26	7.59	2.38	3.19	0.74	20.4	6.4	1.19	.290	3.73	78	3.34	76	8.35	99.9
11	Roger Clemens R. Clemens	3.34	228	229	107	50	.682	1,356	3	1	0	1454.1	1,268	539	596	129	478	45	0	19	6,029	53	8.39	2.96	2.84	0.80	22.5	7.9	1.20	.283	3.69	75	3.42	76	7.85	169.1
12	Randy Johnson R. Johnson	3.34	281	287	143	78	.647	2,182	32	12	0	1885.1	1,616	699	790	212	484	89	3	22	7,686	34	10.42	2.31	4.51	1.01	28.4	6.3	1.11	.298	3.77	75	3.12	70	7.71	275.2
13	Clayton Kershaw C. Kershaw	3.36	51	53	13	13	.500	285	0	0	0	278.2	228	104	106	18	143	2	1	7	1,171	18	9.20	4.62	1.99	0.58	24.3	12.2	1.33	.290	3.42	81	3.46	82	7.36	23.1
14	Rich Harden R. Harden	3.39	127	135	50	29	.633	783	2	1	0	753.2	603	284	311	70	329	16	2	15	3,136	26	9.35	3.93	2.38	0.84	25.0	10.5	1.24	.275	3.71	77	3.57	81	7.20	68.5
15	Roy Halladay R. Halladay	3.40	267	275	139	69	.668	1,400	47	14	0	1883.1	1,832	712	790	151	374	52	4	21	7,712	37	6.69	1.79	3.74	0.72	18.2	4.8	1.17	.293	3.78	74	3.31	74	8.75	243.9
16	Josh Johnson J. Johnson	3.40	76	86	34	16	.680	425	3	0	0	481.1	448	182	198	36	175	12	1	16	2,016	18	7.95	3.27	2.43	0.67	21.1	8.7	1.29	.301	3.70	79	3.49	81	8.38	42.5
17	Felix Hernandez F. Hernandez	3.45	138	138	58	41	.586	810	7	3	0	905.0	863	347	385	80	287	27	0	13	3,786	46	8.06	2.85	2.82	0.80	21.4	7.6	1.27	.303	3.83	80	3.53	82	8.58	80.6
18	Tim Hudson T. Hudson	3.50	289	290	137	76	.643	1,270	21	11	0	1923.1	1,837	749	818	156	570	71	0	59	8,024	52	5.94	2.67	2.23	0.73	15.8	7.1	1.25	.282	3.83	79	3.81	86	8.60	135.6
19	Mark Prior M. Prior	3.51	106	106	42	29	.592	757	5	1	0	657.0	582	256	277	77	223	31	0	10	2,771	21	10.37	3.05	3.39	1.05	27.3	8.0	1.23	.300	3.79	81	3.40	78	7.97	70.6
20	Carlos Zambrano C. Zambrano	3.51	238	259	105	68	.607	1,324	9	4	0	1551.1	1,313	605	669	126	698	81	4	36	6,593	49	7.68	4.05	1.90	0.73	20.1	10.6	1.30	.272	3.88	80	3.94	89	7.62	82.3
21	Matt Cain M. Cain	3.53	137	138	44	51	.463	729	8	2	0	872.1	744	342	357	77	349	21	1	20	3,650	38	7.52	3.60	2.09	0.79	20.0	9.6	1.25	.270	3.68	81	3.88	91	7.68	37.8
22	Darryl Kile D. Kile	3.54	82	82	41	24	.631	421	7	2	0	544.1	525	214	228	64	151	32	0	5	2,280	14	6.96	2.50	2.79	1.06	18.5	6.6	1.24	.286	3.77	81	4.05	90	8.68	28.3
23	Curt Schilling C. Schilling	3.54	221	243	117	63	.650	1,545	26	7	9	1569.1	1,515	618	630	194	257	21	21	9	6,368	23	8.86	1.47	6.01	1.11	24.3	4.0	1.13	.304	3.61	78	3.23	73	8.69	204.8
24	Chad Billingsley C. Billingsley	3.55	100	129	47	30	.610	580	2	1	0	634.0	584	250	269	53	288	21	7	19	2,708	34	8.23	4.09	2.01	0.75	21.4	10.6	1.38	.301	3.82	85	3.86	90	8.29	31.2
25	Yovani Gallardo Y. Gallardo	3.57	51	54	22	17	.564	325	1	0	0	320.0	275	127	131	32	139	7	1	7	1,356	12	9.14	3.91	2.34	0.90	24.0	10.3	1.29	.285	3.68	84	3.78	87	7.73	20.4