47 pitchers are tied for the lowest ERA in a game with an ERA of 50.00 or worse, with an ERA of 54.00. The first three are Ryne Stanek on September 28 and on September 6 and Shinnosuke Ogasawara and Michael Kelly on September 28.

Interpreted as:

lowest era by a player minimum 50 regular-season games

	NAME	ERA	DATE	TM		OPP	DEC	GS	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP
1	Ryne Stanek R. Stanek	54.00	9/28/2025	NYM	@	MIA		0	0	0	0	0	0.1	2	2	2	0	0	0	0	0	3	0
2	Shinnosuke Ogasawara S. Ogasawara	54.00	9/28/2025	WSH	vs	CWS		0	1	0	0	0	0.1	3	2	2	0	1	0	0	0	5	0
3	Michael Kelly M. Kelly	54.00	9/28/2025	ATH	vs	KCR		0	1	0	0	0	0.1	2	2	3	2	0	0	0	0	4	0
4	Steven Wilson S. Wilson	54.00	9/27/2025	CWS	@	WSH		0	0	0	0	0	0.1	2	2	2	1	0	0	0	0	3	0
5	Kyle Hart K. Hart	54.00	9/26/2025	SDP	vs	AZ		0	1	0	0	0	0.1	0	2	2	0	2	0	0	0	3	0
6	Orlando Ribalta O. Ribalta	54.00	9/26/2025	WSH	vs	CWS		0	1	0	0	0	0.1	2	2	2	0	1	0	0	0	4	0
7	Jordan Leasure J. Leasure	54.00	9/26/2025	CWS	@	WSH		0	2	0	0	0	0.2	3	4	4	2	1	0	0	0	6	0
8	Jakob Junis J. Junis	54.00	9/26/2025	CLE	vs	TEX		0	1	0	0	0	0.1	4	2	2	0	0	0	0	0	5	0
9	Justin Wilson J. Wilson	54.00	9/25/2025	BOS	@	TOR		0	0	0	0	0	0.1	2	2	2	1	0	0	0	0	3	0
10	Kevin Kelly K. Kelly	54.00	9/25/2025	TBR	@	BAL	L	0	1	0	0	0	0.1	3	2	2	2	0	0	1	0	4	0
11	Dylan Dodd D. Dodd	54.00	9/21/2025	ATL	@	DET		0	0	0	0	0	0.1	2	2	2	0	1	0	0	0	4	0
12	Kyle Hart K. Hart	54.00	9/21/2025	SDP	@	CWS		0	1	0	0	0	0.1	1	2	2	0	2	0	0	0	4	0
13	Fraser Ellard F. Ellard	54.00	9/20/2025	CWS	vs	SDP		0	1	0	0	0	0.1	1	2	2	0	3	0	0	0	5	2
14	Huascar Brazobán H. Brazobán	54.00	9/19/2025	NYM	vs	WSH		0	1	0	0	0	0.1	2	2	2	1	0	0	0	0	3	0
15	Valente Bellozo V. Bellozo	54.00	9/18/2025	MIA	@	COL		0	0	0	0	0	0.2	4	4	4	2	0	0	0	0	6	0
16	Matt Brash M. Brash	54.00	9/17/2025	SEA	@	KCR	L	0	1	0	0	0	0.2	4	4	4	1	1	0	0	0	7	0
17	David Robertson D. Robertson	54.00	9/16/2025	PHI	@	LAD		0	0	0	0	0	0.1	2	2	2	1	0	0	0	0	3	0
18	Enyel De Los Santos E. De Los Santos	54.00	9/16/2025	HOU	vs	TEX		0	0	0	0	0	0.2	3	4	4	1	1	0	0	0	6	0
19	Chayce McDermott C. McDermott	54.00	9/16/2025	BAL	@	CWS		0	2	0	0	0	0.2	2	4	4	0	1	0	0	0	6	2
20	Joel Peguero J. Peguero	54.00	9/15/2025	SFG	@	AZ		0	0	0	0	0	0.1	1	2	2	0	2	0	0	0	3	0
21	Tyler Alexander T. Alexander	54.00	9/15/2025	CWS	vs	BAL		0	0	0	0	0	0.1	3	2	2	1	0	0	0	0	4	0
22	PJ Poulin	54.00	9/13/2025	WSH	vs	PIT		0	0	0	0	0	0.1	2	2	2	0	1	0	0	0	4	0
23	Cole Henry C. Henry	54.00	9/13/2025	WSH	vs	PIT	L	0	0	0	0	0	0.1	0	2	2	0	2	0	0	0	3	0
24	Rafael Montero R. Montero	54.00	9/13/2025	DET	@	MIA	L	0	0	0	0	0	0.1	2	2	3	1	0	0	1	0	3	0
25	Kyle Nicolas K. Nicolas	54.00	9/12/2025	PIT	@	WSH	L	0	1	0	0	0	0.2	3	4	4	1	1	0	0	0	6	0