Since 1901, James Baldwin had the lowest ERA for the White Sox when pitching over 499 innings with an ERA worse than 4.95, with an ERA of 5.04.
| NAME | ERA | IP | G | W | L | W% | GS | SO | CG | SHO | SV | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Baldwin | 5.04 | 1015.2 | 184 | 69 | 53 | .566 | 165 | 666 | 7 | 2 | 0 | 1,094 | 569 | 612 | 150 | 387 | 38 | 4 | 13 | 4,466 | 51 | 5.90 | 3.43 | 1.72 | 1.33 | 14.9 | 8.7 | 1.46 | .293 | 5.42 | 108 | 4.98 | 106 | 9.69 | -30.5 |
| 2 | | J. Parque | 5.21 | 527.0 | 98 | 30 | 33 | .476 | 92 | 327 | 2 | 0 | 0 | 623 | 305 | 343 | 76 | 225 | 30 | 0 | 4 | 2,397 | 5 | 5.58 | 3.84 | 1.45 | 1.30 | 13.6 | 9.4 | 1.61 | .315 | 5.86 | 109 | 5.20 | 109 | 10.64 | -22.2 |
| 3 | | J. Bere | 5.21 | 551.0 | 104 | 39 | 32 | .549 | 101 | 459 | 2 | 0 | 0 | 523 | 319 | 350 | 71 | 360 | 17 | 0 | 7 | 2,506 | 28 | 7.50 | 5.88 | 1.27 | 1.16 | 18.3 | 14.4 | 1.60 | .283 | 5.72 | 116 | 5.14 | 113 | 8.54 | -38.6 |
| 4 | | J. Navarro | 6.06 | 542.0 | 102 | 25 | 43 | .368 | 87 | 287 | 3 | 0 | 1 | 696 | 365 | 416 | 81 | 221 | 21 | 5 | 8 | 2,507 | 41 | 4.77 | 3.67 | 1.30 | 1.35 | 11.4 | 8.8 | 1.69 | .324 | 6.91 | 132 | 5.34 | 116 | 11.56 | -44.6 |
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