lowest run differential in a game while letting the opponent scoring 0 runs

The Philadelphia Quakers have the lowest run differential by a team in a game with exactly 0 runs, with a differential of -28 runs versus the Providence Grays on August 21, 1883.

Interpreted as:

lowest run differential in a regular-season game while letting the opponent scoring 0 runs

	TEAM	DIFF	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Quakers	-28	0	8/21/1883	PHN	@	PRO	L 0-28
2	Hoosiers	-24	0	6/28/1887	IND	vs	PHN	L 0-24
3	Bisons	-24	0	5/27/1885	BUF	@	NYG	L 0-24
4	Orioles	-23	0	7/6/1883	BAL	@	CIN	L 0-23
5	Yankees	-22	0	8/31/2004	NYY	vs	CLE	L 0-22	32	5	2	0	0	0	1	0	6	0	0	33	7	2	0	0	0	0	.156	.182	.219	.401
6	Cubs	-22	0	9/16/1975	CHC	vs	PIT	L 0-22	30	3	0	0	0	0	0	0	7	0	0	30	3	0	0	0	0	0	.100	.100	.100	.200
7	Pirates	-21	0	4/23/2022	PIT	@	CHC	L 0-21	30	3	1	0	0	0	0	0	5	0	0	30	4	1	0	0	0	0	.100	.100	.133	.233
8	Athletics	-21	0	8/13/1939	PHA	vs	NYY	L 0-21	26	3	1	1	0	0	3	0	5	0	0	30	6	2	1			0	.115	.207	.231	.438
9	Blues	-21	0	9/15/1901	CLE	@	DET	L 0-21	30	6	0	0	0	0	1	1	2	0	-9	32	6	0	0		-9	-9	.200	.250	.200	.450
10	Solons	-21	0	5/7/1889	COL	@	STL	L 0-21
11	Pirates	-20	0	4/22/2010	PIT	vs	MIL	L 0-20	34	8	2	0	0	0	3	0	7	1	1	37	10	2	0	0	0	0	.235	.297	.294	.591
12	Orioles	-20	0	8/10/1889	BAL	@	CIN	L 0-20
13	Nationals	-20	0	5/28/1886	WSH	vs	CWS	L 0-20
14	Tigers	-19	0	9/9/2020	DET	vs	MIL	L 0-19	28	2	0	1	0	0	0	0	11	0	0	28	4	1	0	0	0	1	.071	.071	.143	.214
15	White Sox	-19	0	5/10/2002	CWS	@	ANA	L 0-19	28	3	0	0	0	0	2	0	2	0	1	30	3	0	0	0	0	1	.107	.167	.107	.274
16	Braves	-19	0	7/30/1978	ATL	vs	MON	L 0-19	34	7	0	0	0	0	0	1	5	0	0	35	7	0	0	0	0	0	.206	.229	.206	.434
17	Padres	-19	0	6/28/1969	SDP	vs	LAD	L 0-19	31	5	1	0	0	0	2	0	3	0	0	33	6	1	0	0	0	1	.161	.212	.194	.406
18	Padres	-19	0	5/13/1969	SDP	@	CHC	L 0-19	29	3	1	0	0	0	4	0	10	0	1	33	4	1	0	0	0	0	.103	.212	.138	.350
19	Cardinals	-19	0	8/3/1961	STL	vs	PIT	L 0-19	30	4	0	0	0	0	1	0	7	0	0	31	4	0	0	0	0	1	.133	.161	.133	.295
20	Red Sox	-19	0	5/18/1955	BOS	vs	CLE	L 0-19	30	3	1	0	0	0	3	0	9	0	0	33	4	1	0	0	0	0	.100	.182	.133	.315
21	Athletics	-19	0	4/30/1950	PHA	@	BSA	L 0-19	30	5	0	0	0	0	2	0	2	0	0	32	5	0	0		0	1	.167	.219	.167	.385
22	Giants	-19	0	6/7/1906	NYG	vs	CHC	L 0-19	28	4	0	0	0	0	7	0	2	3		35	4	0	0				.143	.314	.143	.457
23	Senators	-19	0	7/8/1896	WSH	@	PIT	L 0-19
24	Senators	-19	0	7/15/1893	WSH	@	PIT	L 0-19
25	Bisons	-19	0	7/16/1890	BUF	@	BSP	L 0-19