The Philadelphia Athletics had the lowest run differential per game by a team in 1920, with -1.76.

	TEAM	DIFF/G	DIFF	G	SEASON	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	AVG	OBP	SLG	OPS
1	Athletics	-1.76	-274	156	1920	.312	48	106	5,263	558	1,325	219	49	44	465	352	45	575	50	67	5,829	1,774	312	169	.252	.304	.337	.641
2	Tigers	-1.14	-177	155	1920	.396	61	93	5,212	652	1,406	228	72	30	561	485	20	389	76	68	5,933	1,868	330	216	.270	.334	.358	.693
3	Phillies	-0.97	-149	153	1920	.405	62	91	5,264	565	1,385	229	54	64	483	283	36	531	100	83	5,742	1,914	347	159	.263	.305	.364	.669
4	Braves	-0.96	-147	153	1920	.408	62	90	5,218	523	1,358	168	86	23	456	385	33	488	88	98	5,802	1,767	277	166	.260	.315	.339	.654
5	Senators	-0.48	-73	153	1920	.447	68	84	5,252	724	1,525	232	81	36	616	435	54	538	160	110	5,940	2,027	349	199	.290	.351	.386	.737
6	Red Sox	-0.35	-54	154	1920	.471	72	81	5,189	650	1,397	216	71	22	569	527	45	428	98	110	5,980	1,821	309	219	.269	.342	.351	.693
7	Pirates	-0.14	-22	155	1920	.513	79	75	5,219	530	1,342	162	90	16	449	374	29	405	181	117	5,796	1,732	268	174	.257	.310	.332	.642
8	Cubs	-0.1	-16	154	1920	.487	75	79	5,117	619	1,350	223	67	34	535	428	46	421	115	129	5,811	1,809	324	220	.264	.326	.354	.680
9	Cardinals	-0.05	-7	155	1920	.487	75	79	5,495	675	1,589	238	96	32	600	373	26	484	126	114	6,086	2,115	366	192	.289	.337	.385	.722
10	Browns	0.17	26	154	1920	.497	76	77	5,359	797	1,650	278	84	50	707	425	38	338	121	78	6,029	2,246	412	207	.308	.363	.419	.782
11	Reds	0.45	70	154	1920	.536	82	71	5,176	639	1,432	169	76	18	546	382	47	367	158	128	5,799	1,807	263	194	.277	.332	.349	.681
12	Robins	0.84	130	155	1920	.604	93	61	5,399	660	1,493	205	99	28	566	359	19	391	70	80	5,966	1,980	332	189	.277	.324	.367	.691
13	White Sox	0.86	132	154	1920	.623	96	58	5,330	794	1,574	263	98	37	694	474	38	350	109	94	6,030	2,144	398	188	.295	.357	.402	.759
14	Giants	0.9	139	155	1920	.558	86	68	5,309	682	1,427	210	76	46	590	432	26	545	131	113	5,891	1,927	332	124	.269	.327	.363	.690
15	Yankees	1.33	205	154	1920	.617	95	59	5,174	837	1,447	268	71	115	751	532	23	621	64	81	5,901	2,202	454	172	.280	.349	.426	.775
16	Indians	1.38	212	154	1920	.636	98	56	5,203	856	1,575	301	95	35	757	574	36	376	73	93	6,067	2,171	431	254	.303	.376	.417	.793