Luis Castillo has a record of 1-3 with an ERA of 3.77 and 24 strikeouts in 5 appearances against the Yankees on the road in his career.
| NAME | DATE | TM | OPP | DEC | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Luis Castillo | 7/25/2017 |  CIN | @ |  NYY | L | 1 | 5.40 | 2 | 0 | 0 | 0 | 5.0 | 7 | 3 | 3 | 0 | 2 | 0 | 0 | 0 | 22 | 0 |
| | Luis Castillo | 7/14/2022 | CIN | @ | NYY | 1 | 1.29 | 8 | 0 | 0 | 0 | 7.0 | 2 | 1 | 1 | 0 | 4 | 1 | 0 | 0 | 28 | 0 | |
 | Luis Castillo | 8/3/2022 |  SEA | @ | NYY | W | 1 | 4.05 | 8 | 0 | 0 | 0 | 6.2 | 5 | 3 | 3 | 1 | 3 | 0 | 0 | 0 | 27 | 0 |
| | Luis Castillo | 6/21/2023 | SEA | @ | NYY | L | 1 | 5.40 | 3 | 0 | 0 | 0 | 5.0 | 4 | 3 | 3 | 2 | 4 | 0 | 0 | 0 | 22 | 0 |
| | Luis Castillo | 5/23/2024 | SEA | @ | NYY | L | 1 | 3.60 | 3 | 0 | 0 | 0 | 5.0 | 7 | 2 | 2 | 2 | 3 | 1 | 0 | 0 | 24 | 0 |
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| NL East | W | L | PCT | GB | |
|---|---|---|---|---|---|
| 1 |  Braves | 104 | 58 | .642 | |
| 2 |  Phillies | 90 | 72 | .556 | 14.0 |
| AL East | W | L | PCT | GB | |
| 1 |  Orioles | 101 | 61 | .623 | |
| 2 |  Rays | 99 | 63 | .611 | 2.0 |
| NL West | W | L | PCT | GB | |
| 1 |  Dodgers | 100 | 62 | .617 | |
| 2 |  Diamondbacks | 84 | 78 | .519 | 16.0 |
| NL Central | W | L | PCT | GB | |
| 1 |  Brewers | 92 | 70 | .568 | |
| 2 |  Cubs | 83 | 79 | .512 | 9.0 |
| AL West | W | L | PCT | GB | |
| 1 |  Astros | 90 | 72 | .556 | |
| 2 |  Rangers | 90 | 72 | .556 | |
| AL Central | W | L | PCT | GB | |
| 1 |  Twins | 87 | 75 | .537 | |
| 2 |  Tigers | 78 | 84 | .481 | 9.0 |
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