Mark Buehrle was 131-96 with an ERA of 3.79 and 1,151 strikeouts in 298 appearances between the 2001 and 2009 seasons.
| NAME | SEASON | TM | G | W | L | W% | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Buehrle | 2001 |  CWS | 32 | 16 | 8 | .667 | 32 | 3.29 | 126 | 4 | 2 | 0 | 221.1 | 188 | 81 | 89 | 24 | 48 | 8 | 0 | 2 | 885 | 1 | 5.12 | 1.95 | 2.63 | 0.98 | 14.2 | 5.4 | 1.07 | .242 | 3.62 | 73 | 4.07 | 89 | 7.64 | 11.9 |
| 2 | | M. Buehrle | 2002 | CWS | 34 | 19 | 12 | .613 | 34 | 3.58 | 134 | 5 | 2 | 0 | 239.0 | 236 | 95 | 102 | 25 | 61 | 3 | 0 | 7 | 984 | 6 | 5.05 | 2.30 | 2.20 | 0.94 | 13.6 | 6.2 | 1.24 | .277 | 3.84 | 78 | 4.00 | 87 | 8.89 | 15.2 |
| 3 | | M. Buehrle | 2003 | CWS | 35 | 14 | 14 | .500 | 35 | 4.14 | 119 | 2 | 0 | 0 | 230.1 | 250 | 106 | 124 | 22 | 61 | 5 | 0 | 2 | 978 | 1 | 4.65 | 2.38 | 1.95 | 0.86 | 12.2 | 6.2 | 1.35 | .296 | 4.85 | 90 | 4.09 | 87 | 9.77 | 14.9 |
| 4 | | M. Buehrle | 2004 | CWS | 35 | 16 | 10 | .615 | 35 | 3.89 | 165 | 4 | 1 | 0 | 245.1 | 257 | 106 | 119 | 33 | 51 | 8 | 0 | 2 | 1,016 | 0 | 6.05 | 1.87 | 3.24 | 1.21 | 16.2 | 5.0 | 1.26 | .295 | 4.37 | 82 | 4.17 | 88 | 9.43 | 15.6 |
| 5 | | M. Buehrle | 2005 | CWS | 33 | 16 | 8 | .667 | 33 | 3.12 | 149 | 3 | 1 | 0 | 236.2 | 240 | 82 | 99 | 20 | 40 | 4 | 0 | 4 | 971 | 2 | 5.67 | 1.52 | 3.73 | 0.76 | 15.3 | 4.1 | 1.18 | .290 | 3.76 | 70 | 3.41 | 75 | 9.13 | 28.7 |
| 6 | | M. Buehrle | 2006 | CWS | 32 | 12 | 13 | .480 | 32 | 4.99 | 98 | 1 | 0 | 0 | 204.0 | 247 | 113 | 124 | 36 | 48 | 6 | 0 | 5 | 876 | 0 | 4.32 | 2.12 | 2.04 | 1.59 | 11.2 | 5.5 | 1.45 | .307 | 5.47 | 105 | 5.27 | 111 | 10.90 | -11 |
| 7 | | M. Buehrle | 2007 | CWS | 30 | 10 | 9 | .526 | 30 | 3.63 | 115 | 3 | 1 | 0 | 201.0 | 208 | 81 | 86 | 22 | 45 | 5 | 0 | 5 | 835 | 1 | 5.15 | 2.01 | 2.56 | 0.99 | 13.8 | 5.4 | 1.26 | .287 | 3.85 | 78 | 4.25 | 91 | 9.31 | 8.9 |
| 8 | | M. Buehrle | 2008 | CWS | 34 | 15 | 12 | .556 | 34 | 3.79 | 140 | 1 | 0 | 0 | 218.2 | 240 | 92 | 106 | 22 | 52 | 5 | 0 | 4 | 918 | 4 | 5.76 | 2.14 | 2.69 | 0.91 | 15.3 | 5.7 | 1.34 | .312 | 4.36 | 84 | 3.93 | 87 | 9.88 | 14.3 |
| 9 | | M. Buehrle | 2009 | CWS | 33 | 13 | 10 | .565 | 33 | 3.84 | 105 | 1 | 1 | 0 | 213.1 | 222 | 91 | 97 | 27 | 45 | 5 | 0 | 3 | 874 | 2 | 4.43 | 1.90 | 2.33 | 1.14 | 12.0 | 5.1 | 1.25 | .282 | 4.09 | 84 | 4.45 | 97 | 9.37 | 3.3 |
| Total | 298 | 131 | 96 | .577 | 298 | 3.79 | 1,151 | 24 | 8 | 0 | 2009.2 | 2,088 | 847 | 946 | 231 | 451 | 49 | 0 | 34 | 8,337 | 17 | 5.15 | 2.02 | 2.55 | 1.03 | 13.8 | 5.4 | 1.26 | .288 | 4.24 | 82 | 4.16 | 90 | 9.35 | 101.9 |
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