The New York Mets had their most strikeouts in a game versus the Giants on May 31, 1964, with 22 strikeouts.

Interpreted as:

mets most strikeouts in a regular-season game

	TEAM	SO	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Mets	22	5/31/1964	NYM	vs	SFG	L 6-8	85	6	20	1	1	1	6	3	1	0	1	91	26	3	2	0	1	2	.235	.270	.306	.576
2	Mets	21	10/2/1965	NYM	vs	PHI	N 0-0	61	0	9	3	0	0	0	4	1	2	1	66	12	3	0	0	1	1	.148	.212	.197	.409
3	Mets	20	4/15/1968	NYM	@	HOU	L 0-1	79	0	11	1	0	0	0	5	0	2	0	88	12	1	4	0	2	1	.139	.190	.152	.342
4	Mets	19	9/20/2018	NYM	@	WSH	W 5-4	43	5	10	2	1	2	5	6	0	0	0	51	20	5	1	1	1	1	.233	.320	.465	.785
5	Mets	19	5/30/2014	NYM	@	PHI	L 5-6	47	5	8	2	0	0	5	10	0	1	1	59	10	2	2	0	2	0	.170	.316	.213	.529
6	Mets	19	7/8/2013	NYM	@	SFG	W 4-3	55	4	9	1	2	0	2	4	0	2	1	59	14	3	0	0	1	1	.164	.220	.255	.475
7	Mets	19	6/8/2013	NYM	vs	MIA	L 1-2	71	1	13	2	0	0	1	9	2	1	0	83	15	2	1	0	1	1	.183	.293	.211	.504
8	Mets	19	9/15/1969	NYM	@	STL	W 4-3	36	4	9	0	0	2	4	2	0	0	0	38	15	2	0	0	0	0	.250	.289	.417	.706
9	Mets	18	4/8/2018	NYM	@	WSH	W 6-5	42	6	9	2	0	2	6	5	0	1	0	48	17	4	1	0	1	1	.214	.298	.405	.703
10	Mets	18	3/31/2014	NYM	vs	WSH	L 7-9	35	7	7	0	0	3	7	3	0	0	0	40	16	3	1	1	0	0	.200	.256	.457	.714
11	Mets	18	4/10/2005	NYM	@	ATL	W 6-1	38	6	13	3	0	3	6	2	0	2	0	42	25	6	2	0	1	0	.342	.375	.658	1.033
12	Mets	18	6/14/1965	NYM	@	CIN	W 1-0	34	1	2	0	0	1	1	1	0	0	0	35	5	1	0	0	0	2	.059	.086	.147	.233
13	Mets	17	7/8/2023	NYM	@	SDP	L 1-3	29	1	3	0	0	1	1	3	0	0	0	32	6	1	0	0	0	0	.103	.188	.207	.394
14	Mets	17	5/4/2019	NYM	@	MIL	L 3-4	62	3	10	0	1	1	3	1	1	1	0	64	15	2	0	0	0	1	.161	.188	.242	.429
15	Mets	17	4/20/2016	NYM	@	PHI	L 4-5	46	4	14	5	0	2	3	2	1	0	0	49	25	7	0	0	0	1	.304	.347	.543	.890
16	Mets	17	10/3/2015	NYM	vs	WSH	L 0-2	28	0	0	0	0	0	0	0	0	0	0	28	0	0	0	0	0	0	.000	.000	.000	.000
17	Mets	17	4/10/2011	NYM	vs	WSH	L 3-7	41	3	8	0	0	0	3	3	0	1	0	44	8	0	0	0	1	0	.195	.250	.195	.445
18	Mets	17	4/17/2008	NYM	vs	WSH	W 3-2	48	3	9	1	0	0	2	8	0	1	1	58	10	1	2	0	3	1	.188	.304	.208	.512
19	Mets	17	5/16/2004	NYM	@	HOU	W 3-2	46	3	7	1	0	2	3	1	0	1	0	47	14	3	0	0	0	0	.152	.170	.304	.475
20	Mets	17	7/15/1994	NYM	vs	SDP	L 1-2	49	1	7	2	0	0	0	3	0	0	0	52	9	2	0	0	2	0	.143	.192	.184	.376
21	Mets	17	5/6/1983	NYM	vs	CIN	W 7-4	44	7	7	0	0	4	7	4	1	1	0	50	19	4	1	0	0	0	.159	.245	.432	.677
22	Mets	17	5/28/1982	NYM	vs	HOU	L 3-8	36	3	10	1	0	0	3	4	0	0	0	40	11	1	0	0	0	1	.278	.350	.306	.656
23	Mets	17	5/21/1968	NYM	vs	PIT	W 4-3	61	4	13	1	0	1	3	2	1	1	1	65	17	2	1	0	0	1	.213	.250	.279	.529
24	Mets	16	9/1/2024	NYM	@	CWS	W 2-0	33	2	7	1	0	1	2	3	0	0	1	36	11	2	0	0	1	0	.212	.278	.333	.611
25	Mets	16	9/10/2023	NYM	@	MIN	W 2-0	31	2	4	2	0	0	2	0	3	0	0	34	6	2	0	0	0	0	.129	.206	.194	.399