Since July 3, 2025, the Boston Red Sox have the highest run differential by a team, with a differential of 46 runs.

	TEAM	DIFF	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Red Sox	46	10	1.000	10	0	345	70	103	28	3	15	68	27	4	66	12	3	377	182	46	0	1	1	6	.299	.355	.528	.883
2	Brewers	24	10	.800	8	2	328	50	84	13	1	9	48	27	10	72	11	5	367	126	23	0	2	1	7	.256	.330	.384	.714
3	Rangers	21	10	.500	5	5	364	63	94	19	1	15	61	37	5	86	14	0	409	160	35	0	3	1	8	.258	.333	.440	.772
4	Marlins	18	11	.545	6	5	369	52	92	16	1	13	49	24	3	79	7	2	401	149	30	0	5	0	8	.249	.297	.404	.701
5	Mariners	17	10	.600	6	4	348	59	92	20	1	24	56	33	6	94	6	3	388	186	45	0	1	2	4	.264	.338	.534	.872
6	Phillies	11	9	.444	4	5	311	39	78	17	0	10	36	30	3	76	8	2	348	125	27	1	3	0	3	.251	.320	.402	.722
7	Cubs	11	10	.600	6	4	346	49	85	15	2	17	47	30	1	74	6	1	380	155	34	0	3	0	3	.246	.305	.448	.753
8	Blue Jays	11	10	.700	7	3	336	47	88	21	0	12	45	32	3	70	5	0	378	145	33	5	2	4	8	.262	.330	.432	.761
9	Yankees	8	10	.500	5	5	346	61	95	20	1	21	59	26	2	78	3	4	378	180	42	0	4	3	5	.275	.325	.520	.846
10	Twins	7	10	.600	6	4	331	44	83	16	1	16	42	23	5	80	6	3	361	149	33	0	2	0	3	.251	.307	.450	.758
11	Astros	7	10	.400	4	6	357	57	96	24	3	17	55	33	2	91	1	1	399	177	44	1	6	1	7	.269	.329	.496	.825
12	Mets	7	10	.600	6	4	333	49	82	16	2	13	48	33	4	88	8	0	375	141	31	3	2	6	9	.246	.320	.423	.743
13	Royals	7	10	.700	7	3	334	41	86	23	1	15	41	17	9	69	5	4	362	156	39	1	1	0	6	.257	.310	.467	.777
14	Athletics	6	9	.556	5	4	308	48	78	20	1	17	46	29	2	91	6	2	340	151	38	0	1	3	3	.253	.321	.490	.811
15	Guardians	6	11	.545	6	5	372	44	75	20	1	14	44	36	2	90	13	4	421	139	35	6	5	5	3	.202	.272	.374	.646
16	Orioles	-3	9	.667	6	3	297	36	68	17	0	10	35	22	6	75	8	4	326	115	27	0	1	2	5	.229	.294	.387	.682
17	Reds	-4	10	.500	5	5	328	37	78	13	2	9	33	27	3	87	6	0	361	122	24	0	3	3	8	.238	.299	.372	.671
18	Padres	-4	10	.600	6	4	320	31	81	9	1	10	30	35	2	71	7	1	365	122	20	5	3	5	6	.253	.328	.381	.709
19	Diamondbacks	-4	11	.364	4	7	359	44	77	22	2	13	43	44	8	90	5	2	419	142	37	5	3	3	5	.214	.312	.396	.707
20	Rays	-8	10	.200	2	8	341	33	85	17	0	5	29	18	1	78	10	5	367	117	22	2	5	1	5	.249	.285	.343	.628
21	Giants	-8	10	.600	6	4	337	40	75	15	2	8	39	32	6	93	0	0	379	118	25	1	3	3	3	.223	.299	.350	.649
22	Braves	-11	10	.300	3	7	351	41	81	19	0	18	41	21	4	88	1	0	379	154	37	3	0	0	6	.231	.282	.439	.721
23	White Sox	-12	11	.364	4	7	348	40	74	17	1	10	40	40	6	87	3	0	401	123	28	3	4	3	10	.213	.302	.353	.655
24	Angels	-12	11	.455	5	6	382	52	100	16	1	14	52	42	6	97	7	2	436	160	31	1	5	4	6	.262	.340	.419	.759
25	Cardinals	-15	9	.444	4	5	297	41	72	15	0	10	40	29	0	73	7	0	329	117	25	2	1	0	5	.242	.309	.394	.703