mlb highest run differential for a losing team

The Chicago Cubs have the highest run differential by a team this season, with a differential of 109 runs.

Interpreted as:

MLB highest run differential for a losing team this regular season

	TEAM	DIFF	L	SEASON	W	L%	G	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cubs	109	35	2025	52	.402	87	.598	3,006	464	767	151	18	125	455	304	23	680	102	18	3,367	1,329	294	7	27	10	36	.255	.326	.442	.768
2	Dodgers	100	32	2025	56	.364	88	.636	3,007	494	787	149	15	138	476	326	31	717	47	14	3,397	1,380	302	3	30	18	61	.262	.337	.459	.796
3	Yankees	100	39	2025	48	.448	87	.552	2,959	445	753	153	14	131	425	352	36	776	61	20	3,380	1,327	298	4	29	28	59	.254	.338	.448	.786
4	Tigers	99	34	2025	54	.386	88	.614	2,984	446	765	142	19	111	428	281	39	760	30	7	3,339	1,278	272	5	30	7	47	.256	.325	.428	.754
5	Rays	69	39	2025	48	.448	87	.552	2,937	416	760	133	9	100	395	264	28	722	113	27	3,260	1,211	242	8	23	7	61	.259	.323	.412	.736
6	Brewers	56	39	2025	48	.448	87	.552	2,912	409	718	125	8	85	380	305	34	697	99	30	3,295	1,114	218	18	26	10	46	.247	.323	.383	.705
7	Phillies	52	36	2025	51	.414	87	.586	2,952	399	755	135	13	92	380	301	33	686	76	16	3,314	1,192	240	9	19	10	54	.256	.330	.404	.733
8	Astros	48	35	2025	52	.402	87	.598	2,918	367	752	122	9	93	350	250	40	665	47	19	3,239	1,171	224	9	22	7	71	.258	.323	.401	.724
9	Mets	39	38	2025	50	.432	88	.568	2,931	380	714	137	13	112	371	302	53	689	66	10	3,319	1,213	262	4	29	15	71	.244	.322	.414	.736
10	Reds	35	42	2025	45	.483	87	.517	2,920	404	722	143	11	94	384	290	29	755	66	23	3,268	1,169	248	7	22	7	56	.247	.319	.400	.720
11	Cardinals	32	41	2025	47	.466	88	.534	2,985	403	754	151	4	87	383	276	46	682	47	15	3,341	1,174	242	9	25	12	61	.253	.323	.393	.716
12	Giants	30	41	2025	47	.466	88	.534	2,883	366	667	133	15	81	347	312	34	741	45	17	3,274	1,073	229	18	27	6	61	.231	.311	.372	.683
13	Rangers	26	44	2025	43	.506	87	.494	2,887	330	661	121	8	88	316	252	35	713	78	20	3,204	1,062	217	5	25	10	45	.229	.296	.368	.664
14	Red Sox	15	45	2025	43	.511	88	.489	3,030	421	760	172	13	107	402	292	40	811	73	19	3,390	1,279	292	7	21	16	48	.251	.323	.422	.745
15	Mariners	14	42	2025	45	.483	87	.517	2,999	394	745	121	4	114	381	299	47	764	80	22	3,382	1,216	239	15	22	14	57	.248	.324	.405	.729
16	Padres	11	40	2025	46	.465	86	.535	2,859	352	700	127	11	73	328	276	23	605	58	16	3,202	1,068	211	19	25	9	56	.245	.314	.374	.687
17	Braves	9	47	2025	39	.547	86	.453	2,908	348	708	117	9	88	335	301	24	742	43	13	3,260	1,107	214	7	20	10	53	.243	.318	.381	.698
18	Blue Jays	9	38	2025	49	.437	87	.563	2,942	401	761	146	4	92	384	294	34	585	46	15	3,314	1,191	242	18	26	16	64	.259	.330	.405	.735
19	Diamondbacks	4	44	2025	43	.506	87	.494	2,957	451	750	152	18	130	441	306	39	683	62	19	3,353	1,328	300	15	36	9	59	.254	.328	.449	.777
20	Twins	-18	46	2025	41	.529	87	.471	2,910	359	693	135	8	97	346	251	51	722	43	15	3,232	1,135	240	2	18	5	57	.238	.308	.390	.698
21	Pirates	-29	50	2025	38	.568	88	.432	2,910	310	682	117	14	61	300	284	30	761	75	22	3,253	1,010	192	8	21	12	76	.234	.307	.347	.654
22	Royals	-34	47	2025	41	.534	88	.466	2,944	290	713	148	15	58	286	215	31	606	67	29	3,232	1,065	221	19	23	13	44	.242	.298	.362	.660
23	Angels	-46	43	2025	43	.500	86	.500	2,876	371	659	116	10	127	357	241	46	842	38	18	3,188	1,176	253	7	18	11	51	.229	.297	.409	.706
24	Guardians	-52	45	2025	40	.529	85	.471	2,765	309	622	115	8	84	294	264	29	700	65	21	3,097	1,005	207	11	28	12	51	.225	.297	.363	.660
25	Nationals	-68	50	2025	37	.575	87	.425	2,928	388	723	143	12	87	372	255	38	660	77	30	3,257	1,151	242	16	20	10	53	.247	.313	.393	.707