Between the 1920 and 1930 seasons, Babe Ruth launched the most home runs, with 516 home runs.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	PA	TB	XBH	SH	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Babe Ruth B. Ruth	516	1,544	5,402	1,515	1,920	342	91	1,491	1,376	28	856	98	6,900	3,992	949	94	.355	.488	.739	1.227	1894	1,029.6	.533	206	985.5
2	Rogers Hornsby R. Hornsby	252	1,472	5,555	1,210	2,117	410	116	1,171	765	25	443	74	6,509	3,515	778	164	.381	.458	.633	1.091	1550	741.1	.488	185	714.8
3	Cy Williams C. Williams	202	1,260	4,291	722	1,335	202	47	717	494	43	404	58	4,904	2,237	451	76	.311	.388	.521	.909	871	267.6	.414	129	181.5
4	Hack Wilson H. Wilson	193	910	3,332	676	1,072	189	56	795	465	19	472	42	3,911	1,952	438	95	.322	.408	.586	.994	799	300.3	.441	151	273.8
5	Ken Williams K. Williams	190	1,249	4,388	805	1,428	265	68	863	522	24	237	142	5,076	2,399	523	142	.325	.400	.547	.947	961	335.4	.429	137	256.2
6	Lou Gehrig L. Gehrig	187	921	3,327	774	1,139	248	89	808	581	18	414	42	4,024	2,126	524	98	.342	.443	.639	1.082	937	421.7	.476	175	411.4
7	Jim Bottomley J. Bottomley	161	1,193	4,621	803	1,502	294	111	982	450	29	373	45	5,250	2,501	566	150	.325	.388	.541	.930	960	295	.418	136	251.9
8	Harry Heilmann H. Heilmann	161	1,559	5,744	1,041	2,077	440	107	1,222	679	26	374	72	6,654	3,214	708	205	.362	.431	.560	.991	1379	546.2	.449	152	473.1
9	Bob Meusel B. Meusel	156	1,407	5,475	826	1,693	368	95	1,071	375	21	619	143	6,028	2,719	619	157	.309	.356	.497	.852	937	181.7	.386	117	133.2
10	Al Simmons A. Simmons	151	958	3,836	711	1,380	278	76	878	245	10	282	58	4,189	2,263	505	98	.360	.400	.590	.990	850	314.9	.440	147	268
11	Goose Goslin G. Goslin	145	1,292	4,930	832	1,616	276	122	960	486	42	335	126	5,600	2,571	543	142	.328	.393	.522	.914	1004	293.4	.413	134	261.2
12	High Pockets Kelly H. Pockets Kelly	142	1,441	5,540	776	1,678	320	71	977	353	27	607	63	6,068	2,566	533	148	.303	.348	.463	.811	866	107.4	.370	112	93.1
13	Jack Fournier J. Fournier	121	1,059	3,748	621	1,213	186	69	657	424	61	256	78	4,340	1,900	376	107	.324	.401	.507	.908	778	243.1	.416	144	240.9
14	Gabby Hartnett G. Hartnett	118	850	2,706	387	802	174	34	486	307	18	322	22	3,099	1,398	326	68	.296	.372	.517	.888	524	130.2	.399	126	108.9
15	Chick Hafey C. Hafey	111	690	2,503	448	806	207	38	523	192	19	260	45	2,783	1,422	356	69	.322	.375	.568	.943	516	157.4	.417	133	127.4
16	Marty McManus M. McManus	100	1,389	5,133	814	1,515	313	77	823	501	25	442	109	5,835	2,282	490	176	.295	.361	.445	.805	839	99.1	.370	102	18.3
17	Irish Meusel I. Meusel	97	1,029	3,904	588	1,230	199	80	698	224	14	165	71	4,247	1,880	376	105	.315	.354	.482	.836	640	117	.381	118	100.4
18	Bill Terry B. Terry	95	914	3,272	571	1,115	196	57	605	298	4	246	34	3,659	1,710	348	85	.341	.396	.523	.919	670	198.8	.414	134	174.6
19	Chuck Klein C. Klein	94	369	1,517	325	560	118	18	349	122	5	133	9	1,673	996	230	29	.369	.418	.657	1.074	388	163.7	.466	148	120
20	Travis Jackson T. Jackson	94	1,015	3,715	544	1,115	189	55	574	271	5	324	51	4,114	1,696	338	123	.300	.349	.457	.805	583	60.2	.366	107	40.2
21	Bing Miller B. Miller	94	1,332	4,891	760	1,562	302	82	787	284	64	279	110	5,431	2,310	478	192	.319	.365	.472	.837	831	141.4	.381	111	80.9
22	Babe Herman B. Herman	93	700	2,577	441	893	188	50	488	242	8	231	52	2,898	1,460	331	71	.347	.404	.567	.971	577	204	.433	144	181.8
23	George Harper G. Harper	91	913	2,998	476	942	149	41	497	355	31	171	53	3,471	1,446	281	87	.314	.392	.482	.875	586	149.6	.402	125	115.1
24	Frankie Frisch F. Frisch	87	1,511	6,094	1,113	1,995	323	116	852	491	23	180	325	6,784	2,811	526	176	.327	.380	.461	.841	1066	214.5	.386	120	181.3
25	Mel Ott M. Ott	86	539	1,724	359	570	106	14	370	282	10	127	21	2,060	962	206	44	.331	.428	.558	.986	428	157.6	.440	145	137.3