Carl Weilman has the most strikeouts by a pitcher in a game, with 6 strikeouts versus the Washington Senators on July 25, 1913.
Interpreted as:
MLB most k by a player pitched in a regular-season game| NAME | SO | DATE | TM | OPP | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Weilman | 6 | 7/25/1913 |  SLA | @ |  WSH | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | |||||
| 2 |  | G. Cole | 5 | 5/4/2018 |  HOU | @ |  ARI | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | | T. Lilly | 5 | 6/30/2008 |  CHC | @ |  SFG | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | | C. Hensley | 5 | 5/14/2006 |  SDP | @ | CHC | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | | B. Blyleven | 5 | 7/27/1979 |  PIT | @ |  MON | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | | R. Jarvis | 5 | 4/20/1969 |  BOS | vs |  CLE | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | | S. Bahnsen | 5 | 6/17/1968 |  NYY | @ |  CAL | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | | B. Sadowski | 5 | 4/20/1964 |  MIL | @ |  LAD | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | | R. Kline | 5 | 9/22/1958 | PIT | @ |  PHI | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 10 | | J. Broaca | 5 | 6/25/1934 | NYY | vs |  CWS | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | |||
| 11 | | L. Grove | 5 | 6/10/1933 |  PHA | vs | NYY | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | |||
| 12 | | S. Perry | 5 | 4/28/1919 | PHA | @ | NYY | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 13 | | L. Williams | 5 | 5/15/1918 | CWS | @ | WSH | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | ||||
| 14 | | C. Morgan | 5 | 9/18/1911 | PHA | vs | CWS | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 15 | | B. Harmon | 5 | 7/7/1911 |  SLN | @ | PHN | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | |||
| 16 | | S. Sallee | 5 | 7/21/1908 | SLN | vs |  NYG | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 17 | | G. Winter | 5 | 9/5/1905 |  BSA | vs | PHA | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 18 | | B. Bernhard | 5 | 8/11/1904 |  CLE | vs | PHA | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 19 | | C. Hernández | 4 | 8/22/2021 |  KCR | @ | CHC | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | | E. Lauer | 4 | 7/3/2021 |  MIL | @ | PIT | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 | | T. Rogers | 4 | 6/10/2021 |  MIA | vs |  COL | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 |  | T. Anderson | 4 | 5/9/2021 | PIT | @ | CHC | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 23 | | T. Beede | 4 | 7/2/2019 | SFG | @ |  SDP | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | | J. Quintana | 4 | 9/24/2017 | CHC | @ |  MIL | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25 | | M. Pérez | 4 | 8/9/2017 |  TEX | @ |  NYM | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1916 season.
Some of the information used here was obtained free of charge from Retrosheet.
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