Between the 1930 and 1939 seasons, Jimmie Foxx had the most strikeouts, with 876 strikeouts.

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	PA	TB	XBH	SH	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Jimmie Foxx J. Foxx	876	1,470	5,495	1,244	1,845	316	87	415	1,403	1,015	7	65	6,552	3,580	818	35	17	.336	.440	.652	1.091	1555	726.8	.479	166	611.7
2	Wally Berger W. Berger	685	1,328	5,120	806	1,537	297	59	241	893	431	38	35	5,616	2,675	597	27	6	.300	.359	.522	.881	946	235.6	.394	136	259.4
3	Dolph Camilli D. Camilli	592	891	3,237	583	923	160	52	148	563	557	16	34	3,826	1,631	360	16	12	.285	.393	.504	.897	680	198.1	.407	133	156.3
4	Tony Lazzeri T. Lazzeri	591	1,169	4,189	652	1,175	210	71	114	787	635	14	86	4,880	1,869	395	42	3	.280	.377	.446	.823	760	141.6	.378	116	108.4
5	Hank Greenberg H. Greenberg	556	882	3,358	698	1,086	262	53	206	851	517	11	43	3,917	2,072	521	31	8	.323	.415	.617	1.032	852	365.8	.457	152	291.9
6	Frankie Crosetti F. Crosetti	542	1,086	4,238	738	1,079	203	50	78	472	555	68	84	4,918	1,616	331	57	11	.255	.350	.381	.731	621	6.2	.343	93	-49.7
7	Ben Chapman B. Chapman	485	1,431	5,518	1,009	1,697	346	100	83	880	708	24	269	6,336	2,492	529	86	19	.308	.389	.452	.840	1025	225.9	.386	118	160.1
8	Bob Johnson B. Johnson	478	1,023	3,814	728	1,168	217	53	186	750	593	8	61	4,436	2,049	456	21	12	.306	.401	.537	.938	843	289.5	.423	133	207.4
9	Mel Ott M. Ott	474	1,473	5,341	1,095	1,673	287	54	308	1,135	956	30	50	6,388	2,992	649	61	5	.313	.420	.560	.980	1315	508.3	.439	163	512.2
10	Al Simmons A. Simmons	458	1,305	5,233	930	1,700	292	89	190	1,081	396	21	39	5,680	2,740	571	30	13	.325	.375	.524	.898	999	281.7	.402	126	208.5
11	Bruce Campbell B. Campbell	455	994	3,575	590	1,052	235	67	78	566	398	21	48	4,021	1,655	380	27	6	.294	.368	.463	.831	626	127.2	.379	108	48.9
12	Joe Cronin J. Cronin	452	1,391	5,332	885	1,650	386	90	108	1,036	716	30	69	6,177	2,540	584	99	18	.309	.394	.476	.871	1058	279.2	.398	121	184.9
13	Lyn Lary L. Lary	448	1,195	4,313	752	1,163	237	53	33	497	677	21	158	5,095	1,605	323	84	5	.270	.371	.372	.744	681	32.1	.352	94	-41.6
14	Earl Averill E. Averill	447	1,445	5,621	1,102	1,786	354	114	218	1,046	705	29	57	6,392	3,022	686	37	4	.318	.397	.538	.934	1208	401	.419	132	288.2
15	Lou Gehrig L. Gehrig	439	1,397	5,255	1,257	1,802	328	91	347	1,360	1,028	30	72	6,339	3,353	766	26	2	.343	.453	.638	1.091	1522	719.6	.481	174	666.9
16	Dick Bartell D. Bartell	435	1,358	5,216	781	1,504	325	48	54	476	464	64	67	5,949	2,087	427	205	10	.288	.354	.400	.754	786	36.7	.349	98	-12.8
17	Sam West S. West	435	1,316	4,906	782	1,502	286	84	68	668	565	4	35	5,561	2,160	438	86	5	.306	.378	.440	.819	856	155.3	.377	107	56
18	Woody English W. English	432	914	3,329	556	949	171	41	28	308	457	23	39	3,873	1,286	240	64		.285	.375	.386	.761	542	48.7	.357	106	36.5
19	Gus Suhr G. Suhr	428	1,425	5,151	710	1,442	288	114	82	813	713	10	53	5,959	2,204	484	85	1	.280	.369	.428	.796	873	119.6	.367	114	107.5
20	Gabby Hartnett G. Hartnett	416	1,180	4,020	541	1,220	245	33	149	777	431	17	6	4,538	1,978	427	70	11	.303	.373	.492	.865	757	182.2	.391	130	175.6
21	Kiki Cuyler K. Cuyler	411	1,082	4,128	687	1,294	225	76	58	572	379	40	118	4,633	1,845	359	86		.313	.377	.447	.824	723	130.6	.377	120	124.8
22	Harlond Clift H. Clift	409	891	3,254	662	935	182	41	123	518	609	31	41	3,924	1,568	346	30	6	.287	.404	.482	.886	696	200.8	.407	118	103.7
23	Pepper Martin P. Martin	401	1,024	3,790	702	1,127	251	71	54	458	331	11	136	4,150	1,682	376	18	7	.297	.356	.444	.799	598	81.9	.365	113	66.7
24	Pinky Higgins P. Higgins	398	1,013	3,791	555	1,143	222	36	86	651	433	8	43	4,280	1,695	344	48	14	.302	.374	.447	.821	658	124.3	.378	106	36.7
25	Chuck Klein C. Klein	395	1,344	5,149	955	1,676	323	62	238	979	479	11	71	5,689	2,837	623	50	4	.326	.384	.551	.935	1067	347	.417	138	278.5