Since 1950, Greg Maddux has won the most games, with 355 wins.

Interpreted as:

MLB most regular-season wins by a player since 1950

	NAME	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Greg Maddux G. Maddux	355	227	.610	744	740	3.16	3,371	109	35	0	5008.1	4,726	1,756	1,981	353	999	137	3	177	20,421	70	6.06	1.80	3.37	0.63	16.5	4.9	1.14	.281	3.56	76	3.25	78	8.49	519.5
2	Roger Clemens R. Clemens	354	184	.658	709	707	3.12	4,672	118	46	0	4916.2	4,185	1,707	1,885	363	1,580	159	0	63	20,240	143	8.55	2.89	2.96	0.66	23.1	7.8	1.17	.284	3.45	70	3.08	71	7.66	680.4
3	Steve Carlton S. Carlton	329	244	.574	741	709	3.22	4,136	254	55	2	5217.2	4,672	1,864	2,130	414	1,833	53	13	150	21,683	183	7.13	3.16	2.26	0.71	19.1	8.5	1.25	.279	3.67	87	3.14	86	8.06	271.5
4	Nolan Ryan N. Ryan	324	292	.526	807	773	3.19	5,714	222	61	3	5386.0	3,923	1,911	2,178	321	2,795	158	13	78	22,575	277	9.55	4.67	2.04	0.54	25.3	12.4	1.25	.265	3.64	90	2.96	83	6.56	370.2
5	Don Sutton D. Sutton	324	256	.559	774	756	3.26	3,574	178	58	5	5282.1	4,692	1,914	2,104	472	1,343	82	12	102	21,631	112	6.09	2.29	2.66	0.80	16.5	6.2	1.14	.261	3.58	92	3.23	90	7.99	181.2
6	Phil Niekro P. Niekro	318	274	.537	864	716	3.35	3,342	245	45	29	5404.0	5,044	2,012	2,337	482	1,809	123	83	86	22,677	226	5.57	3.01	1.85	0.80	14.7	8.0	1.27	.270	3.89	87	3.61	95	8.40	116.1
7	Gaylord Perry G. Perry	314	265	.542	777	690	3.11	3,534	303	53	10	5350.0	4,938	1,846	2,128	399	1,379	108	33	164	21,953	160	5.95	2.32	2.56	0.67	16.1	6.3	1.18	.275	3.58	85	3.06	85	8.31	312.9
8	Tom Seaver T. Seaver	311	205	.603	656	647	2.86	3,640	231	61	1	4783.0	3,971	1,521	1,674	380	1,390	76	6	116	19,369	126	6.85	2.62	2.62	0.72	18.8	7.2	1.12	.259	3.15	79	3.03	85	7.47	286.1
9	Tom Glavine T. Glavine	305	203	.600	682	682	3.54	2,607	56	25	0	4413.1	4,298	1,734	1,900	356	1,500	66	0	145	18,604	65	5.32	3.06	1.74	0.73	14.0	8.1	1.31	.280	3.87	86	3.94	94	8.76	120.1
10	Randy Johnson R. Johnson	303	166	.646	618	603	3.29	4,875	100	37	2	4135.1	3,346	1,513	1,703	411	1,497	190	7	37	17,067	109	10.61	3.26	3.26	0.89	28.6	8.8	1.17	.291	3.71	75	3.18	73	7.28	554.3
11	Warren Spahn W. Spahn	298	204	.594	608	539	3.10	2,121	310	49	23	4253.1	3,933	1,463	1,628	367	1,140	36	55	60	17,458	64	4.49	2.41	1.86	0.78	12.1	6.5	1.19	.259	3.44	85	3.45	96	8.32	77
12	Tommy John T. John	288	231	.555	760	700	3.34	2,245	162	46	3	4710.1	4,783	1,749	2,017	302	1,259	98	22	102	19,692	187	4.29	2.41	1.78	0.58	11.4	6.4	1.28	.284	3.85	90	3.37	89	9.14	208.3
13	Bert Blyleven B. Blyleven	287	250	.534	692	685	3.31	3,701	242	60	0	4970.0	4,632	1,830	2,029	430	1,322	155	3	71	20,491	114	6.70	2.39	2.80	0.78	18.1	6.5	1.20	.282	3.67	85	3.18	82	8.39	368.6
14	Fergie Jenkins F. Jenkins	284	226	.557	664	594	3.34	3,192	267	49	7	4500.2	4,142	1,669	1,853	484	997	84	37	116	18,400	62	6.38	1.99	3.20	0.97	17.3	5.4	1.14	.268	3.71	87	3.27	88	8.28	222.9
15	Jim Kaat J. Kaat	283	237	.544	898	625	3.45	2,461	180	31	17	4530.1	4,620	1,738	2,038	395	1,083	122	102	116	19,023	128	4.89	2.15	2.27	0.78	12.9	5.7	1.26	.282	4.05	93	3.41	91	9.18	165.8
16	Mike Mussina M. Mussina	270	153	.638	537	536	3.68	2,813	57	23	0	3562.2	3,460	1,458	1,559	376	785	60	0	29	14,593	71	7.11	1.98	3.58	0.95	19.3	5.4	1.19	.292	3.94	82	3.57	79	8.74	372.8
17	Jamie Moyer J. Moyer	269	209	.563	696	638	4.25	2,441	33	10	0	4074.0	4,231	1,926	2,076	522	1,155	146	15	69	17,356	57	5.39	2.55	2.11	1.15	14.1	6.7	1.32	.283	4.59	97	4.46	102	9.35	-33.5
18	Jim Palmer J. Palmer	268	152	.638	558	521	2.86	2,212	211	53	4	3948.0	3,349	1,253	1,395	303	1,311	38	15	37	16,114	85	5.04	2.99	1.69	0.69	13.7	8.1	1.18	.249	3.18	80	3.50	95	7.63	83.2
19	Justin Verlander J. Verlander	266	158	.627	555	555	3.32	3,553	26	9	0	3567.2	3,046	1,317	1,428	371	1,004	121	0	28	14,607	99	8.96	2.53	3.54	0.94	24.3	6.9	1.14	.280	3.60	79	3.43	81	7.68	310.9
20	Robin Roberts R. Roberts	264	221	.544	613	558	3.40	2,178	285	42	21	4315.1	4,205	1,629	1,798	480	766	45	40	69	17,637	31	4.54	1.60	2.84	1.00	12.3	4.3	1.15	.263	3.75	89	3.49	91	8.77	169
21	Andy Pettitte A. Pettitte	256	153	.626	531	521	3.85	2,448	26	4	0	3316.0	3,448	1,418	1,572	288	1,031	55	3	42	14,074	69	6.64	2.80	2.37	0.78	17.4	7.3	1.35	.308	4.27	86	3.73	83	9.36	282.1
22	Jack Morris J. Morris	254	186	.577	549	527	3.90	2,478	175	28	0	3824.0	3,567	1,657	1,815	389	1,390	58	10	99	16,120	206	5.83	3.27	1.78	0.92	15.4	8.6	1.30	.269	4.27	96	3.93	95	8.40	93
23	CC Sabathia	251	161	.609	561	560	3.74	3,093	38	12	0	3577.1	3,404	1,485	1,623	382	1,099	123	0	44	14,989	74	7.78	2.76	2.81	0.96	20.6	7.3	1.26	.294	4.08	87	3.77	87	8.56	223.7
24	Bob Gibson B. Gibson	251	174	.591	528	482	2.91	3,117	255	56	6	3884.1	3,279	1,258	1,420	257	1,336	102	21	118	16,068	108	7.22	3.10	2.33	0.60	19.4	8.3	1.19	.268	3.29	78	2.89	81	7.60	290.5
25	Bartolo Colon B. Colon	247	188	.568	565	552	4.12	2,535	38	13	0	3461.2	3,593	1,584	1,719	439	948	64	2	47	14,655	45	6.59	2.46	2.67	1.14	17.3	6.5	1.31	.296	4.47	95	4.14	96	9.34	71.6