Between the 2000 and 2009 seasons, Livan Hernandez pitched the most innings, with 2201.1 innings.

	NAME	IP	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Livan Hernandez L. Hernandez	2201.1	332	129	124	.510	332	4.46	1,335	36	7	0	2,450	1,091	1,165	250	720	57	0	57	9,533	29	5.46	2.94	1.85	1.02	14.0	7.6	1.44	.307	4.76	104	4.40	102	10.02	-19.5
2	Javier Vazquez J. Vazquez	2163.0	328	128	116	.525	327	3.98	2,001	23	6	0	2,101	957	1,025	269	528	64	0	40	9,023	59	8.33	2.20	3.79	1.12	22.2	5.9	1.22	.297	4.26	89	3.66	82	8.74	195
3	Mark Buehrle M. Buehrle	2061.0	326	135	97	.582	301	3.80	1,188	24	8	0	2,143	871	973	236	470	52	6	35	8,562	17	5.19	2.05	2.53	1.03	13.9	5.5	1.27	.288	4.25	82	4.16	90	9.36	106
4	Barry Zito B. Zito	1999.0	321	133	106	.556	320	3.84	1,501	10	4	0	1,775	852	929	209	826	81	0	36	8,484	36	6.76	3.72	1.82	0.94	17.7	9.7	1.30	.267	4.18	88	4.29	98	7.99	23.4
5	Jamie Moyer J. Moyer	1980.1	321	140	94	.598	315	4.23	1,178	11	3	0	2,025	931	989	270	550	80	2	31	8,414	21	5.35	2.50	2.14	1.23	14.0	6.5	1.30	.277	4.49	97	4.61	105	9.20	-46.8
6	Jeff Suppan J. Suppan	1965.2	324	115	110	.511	321	4.55	1,079	11	4	0	2,168	993	1,093	260	683	83	0	47	8,608	70	4.94	3.13	1.58	1.19	12.5	7.9	1.45	.293	5.00	102	4.87	110	9.93	-92
7	Greg Maddux G. Maddux	1939.2	308	134	101	.570	308	3.70	1,211	16	7	0	1,965	797	877	196	308	57	0	59	7,964	24	5.62	1.43	3.93	0.91	15.2	3.9	1.17	.286	4.07	86	3.70	85	9.12	147.3
8	Tim Hudson T. Hudson	1923.1	290	137	76	.643	289	3.50	1,270	21	11	0	1,837	749	818	156	570	71	0	59	8,024	52	5.94	2.67	2.23	0.73	15.8	7.1	1.25	.282	3.83	79	3.81	86	8.60	135.6
9	CC Sabathia	1889.1	288	136	81	.627	288	3.62	1,590	28	11	0	1,738	760	827	168	590	59	0	22	7,834	36	7.57	2.81	2.69	0.80	20.3	7.5	1.23	.289	3.94	82	3.58	82	8.28	166.2
10	Randy Johnson R. Johnson	1885.1	287	143	78	.647	281	3.34	2,182	32	12	0	1,616	699	790	212	484	89	3	22	7,686	34	10.42	2.31	4.51	1.01	28.4	6.3	1.11	.298	3.77	75	3.12	70	7.71	275.2
11	Roy Halladay R. Halladay	1883.1	275	139	69	.668	267	3.40	1,400	47	14	0	1,832	712	790	151	374	52	4	21	7,712	37	6.69	1.79	3.74	0.72	18.2	4.8	1.17	.293	3.78	74	3.31	74	8.75	243.9
12	Andy Pettitte A. Pettitte	1882.0	303	148	89	.624	300	3.90	1,441	11	3	0	1,975	815	917	165	545	32	1	29	8,008	31	6.89	2.61	2.64	0.79	18.0	6.8	1.34	.311	4.39	87	3.61	81	9.44	179.8
13	Kevin Millwood K. Millwood	1860.2	307	115	103	.528	305	4.18	1,398	15	4	0	1,923	865	937	201	578	56	0	35	7,982	41	6.76	2.80	2.42	0.97	17.5	7.2	1.34	.300	4.53	94	4.00	90	9.30	87.6
14	Derek Lowe D. Lowe	1833.2	410	130	99	.568	270	3.81	1,177	9	3	66	1,863	776	885	149	519	54	115	39	7,746	32	5.78	2.55	2.27	0.73	15.2	6.7	1.30	.293	4.34	86	3.79	87	9.14	114.6
15	Jon Garland J. Garland	1829.1	311	117	102	.534	288	4.42	960	10	6	1	1,944	898	992	228	593	53	9	27	7,827	40	4.72	2.92	1.62	1.12	12.3	7.6	1.39	.286	4.88	97	4.71	103	9.56	-22.8
16	Roy Oswalt R. Oswalt	1803.1	283	137	70	.662	271	3.23	1,473	18	6	0	1,756	647	695	154	412	66	5	30	7,455	21	7.35	2.06	3.58	0.77	19.8	5.5	1.20	.299	3.47	75	3.34	76	8.76	208.1
17	Mike Mussina M. Mussina	1790.2	283	134	87	.606	282	3.87	1,488	18	9	0	1,801	769	828	194	364	41	0	14	7,379	35	7.48	1.83	4.09	0.98	20.2	4.9	1.21	.304	4.16	86	3.50	78	9.05	192.8
18	Tom Glavine T. Glavine	1753.2	283	118	87	.576	283	3.77	948	11	7	0	1,769	734	790	178	600	30	0	59	7,431	10	4.87	3.08	1.58	0.91	12.8	8.1	1.35	.280	4.05	89	4.39	101	9.08	-6.9
19	Tim Wakefield T. Wakefield	1747.0	346	110	95	.537	250	4.33	1,209	7	0	7	1,664	840	928	224	616	107	30	18	7,477	71	6.23	3.17	1.96	1.15	16.2	8.2	1.31	.271	4.78	93	4.60	106	8.57	-55.8
20	Jarrod Washburn J. Washburn	1728.0	281	97	101	.490	279	4.03	1,016	9	4	1	1,724	774	824	223	516	61	1	20	7,308	28	5.29	2.69	1.97	1.16	13.9	7.1	1.30	.273	4.29	92	4.58	104	8.98	-38.7
21	Johan Santana J. Santana	1709.2	310	122	60	.670	234	3.12	1,733	9	6	1	1,430	592	641	187	473	34	23	10	6,946	65	9.12	2.49	3.66	0.98	24.9	6.8	1.11	.275	3.37	70	3.37	78	7.53	181.5
22	Brad Penny B. Penny	1633.2	279	105	84	.556	275	4.14	1,141	4	2	0	1,669	752	806	159	526	44	1	34	6,930	40	6.29	2.90	2.17	0.88	16.5	7.6	1.34	.298	4.44	98	4.00	93	9.19	57
23	Jeff Weaver J. Weaver	1630.0	282	90	106	.459	245	4.58	1,074	16	7	2	1,773	830	889	195	440	106	11	37	7,056	37	5.93	2.43	2.44	1.08	15.2	6.2	1.36	.301	4.91	105	4.31	98	9.79	12.1
24	Doug Davis D. Davis	1629.0	287	90	97	.481	269	4.26	1,206	7	3	0	1,687	771	837	169	736	39	4	26	7,162	60	6.66	4.07	1.64	0.93	16.8	10.3	1.49	.303	4.62	94	4.38	98	9.32	19.5
25	Kenny Rogers K. Rogers	1601.1	260	105	78	.574	257	4.51	854	7	3	0	1,771	802	877	173	524	72	1	16	6,962	28	4.80	2.95	1.63	0.97	12.3	7.5	1.43	.299	4.93	96	4.52	100	9.95	4.9