Sammy Sosa had the most RBIs in 2001, with 160 RBIs.

	NAME	RBI	SEASON	TM	G	AB	R	H	2B	3B	HR	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Sammy Sosa S. Sosa	160	2001	CHC	160	577	146	189	34	5	64	116	6	153	0	2	711	425	103	0	12	37	6	.328	.437	.737	1.174	171	82.7	.465	186	79.8
2	Todd Helton T. Helton	146	2001	COL	159	587	132	197	54	2	49	98	5	104	7	5	696	402	105	1	5	15	14	.336	.432	.685	1.116	163	76.6	.457	160	54.8
3	Luis Gonzalez L. Gonzalez	142	2001	ARI	162	609	128	198	36	7	57	100	14	83	1	1	728	419	100	0	5	24	14	.325	.429	.688	1.117	168	77.8	.454	173	69.4
4	Bret Boone B. Boone	141	2001	SEA	158	623	118	206	37	3	37	40	9	110	5	5	690	360	77	5	13	5	11	.331	.372	.578	.950	126	40.5	.397	149	42.5
5	Juan Gonzalez J. Gonzalez	140	2001	CLE	140	532	97	173	34	1	35	41	6	94	1	0	595	314	70	0	16	5	18	.325	.370	.590	.960	109	35.2	.397	145	34
6	Barry Bonds B. Bonds	137	2001	SFG	153	476	129	156	32	2	73	177	9	93	13	3	664	411	107	0	2	35	5	.328	.515	.863	1.379	200	117.7	.537	234	116.6
7	Alex Rodriguez A. Rodriguez	135	2001	TEX	162	632	133	201	34	1	52	75	16	131	18	3	732	393	87	0	9	6	17	.318	.399	.622	1.021	151	60.3	.425	159	54.3
8	Jeff Bagwell J. Bagwell	130	2001	HOU	161	600	126	173	43	4	39	106	6	135	11	3	717	341	86	0	5	5	20	.288	.397	.568	.966	137	48.3	.407	143	40
9	Albert Pujols A. Pujols	130	2001	STL	161	590	112	194	47	4	37	69	9	93	1	3	676	360	88	1	7	6	21	.329	.403	.610	1.013	139	54.7	.423	159	51.9
10	Lance Berkman L. Berkman	126	2001	HOU	156	577	110	191	55	5	34	92	13	121	7	9	688	358	94	0	6	5	8	.331	.430	.620	1.051	151	65.5	.440	164	57.5
11	Phil Nevin P. Nevin	126	2001	SDP	149	546	97	167	31	0	41	71	4	147	4	4	624	321	72	0	3	7	13	.306	.388	.588	.976	120	42.9	.408	154	44.2
12	Shawn Green S. Green	125	2001	LAD	161	619	121	184	31	4	49	72	5	107	20	4	701	370	84	0	5	10	10	.297	.372	.598	.970	131	44.5	.402	149	45
13	Manny Ramirez M. Ramirez	125	2001	BOS	142	529	93	162	33	2	41	81	8	147	0	1	620	322	76	0	2	25	9	.306	.405	.609	1.014	123	46.1	.415	155	43.3
14	Richie Sexson R. Sexson	125	2001	MIL	158	598	94	162	24	3	45	60	6	178	2	4	667	327	72	0	3	5	20	.271	.342	.547	.889	108	25.6	.373	124	21.2
15	Jim Thome J. Thome	124	2001	CLE	156	526	101	153	26	1	49	111	4	185	0	1	644	328	76	0	3	14	9	.291	.416	.624	1.040	136	55.7	.429	167	54.4
16	Garret Anderson G. Anderson	123	2001	ANA	161	672	83	194	39	2	28	27	0	100	13	6	704	321	69	0	5	4	12	.289	.314	.478	.792	92	4.3	.334	104	3.8
17	Rafael Palmeiro R. Palmeiro	123	2001	TEX	160	600	98	164	33	0	47	101	7	90	1	1	714	338	80	0	6	8	8	.273	.381	.563	.944	130	41.3	.396	139	35.4
18	Larry Walker L. Walker	123	2001	COL	142	497	107	174	35	3	38	82	14	103	14	5	601	329	76	0	8	6	9	.350	.449	.662	1.111	143	67.9	.461	162	49
19	Jason Giambi J. Giambi	120	2001	OAK	154	520	109	178	47	2	38	129	13	83	2	0	671	343	87	0	9	24	17	.342	.477	.660	1.137	162	78.3	.465	193	78.7
20	Edgar Martinez E. Martinez	116	2001	SEA	132	470	80	144	40	1	23	93	9	90	4	1	581	255	64	0	9	9	11	.306	.423	.543	.966	112	39.8	.408	157	41.6
21	Eric Chavez E. Chavez	114	2001	OAK	151	552	91	159	43	0	32	41	4	99	8	2	604	298	75	0	7	9	7	.288	.338	.540	.878	94	19	.364	125	19.3
22	Ryan Klesko R. Klesko	113	2001	SDP	146	538	105	154	34	6	30	88	3	89	23	4	638	290	70	0	9	7	16	.286	.384	.539	.923	112	32.8	.388	141	34.1
23	Tino Martinez T. Martinez	113	2001	NYY	154	589	89	165	24	2	34	42	2	89	1	2	635	295	60	0	2	2	12	.280	.329	.501	.830	92	13.6	.352	117	13.9
24	Magglio Ordonez M. Ordonez	113	2001	CWS	160	593	97	181	40	1	31	70	5	70	25	7	671	316	72	0	3	7	14	.305	.382	.533	.914	118	34.3	.388	138	32.1
25	Miguel Tejada M. Tejada	113	2001	OAK	162	622	107	166	31	3	31	43	13	89	11	5	683	296	65	1	4	5	14	.267	.326	.476	.801	92	7.7	.340	109	8