The New York Mutuals have the lowest run differential by a team in a May game, with a differential of -25 runs against the Hartford Dark Blues on May 13, 1876.
Interpreted as:
MLB team lowest run diff in a may regular-season game| TEAM | DIFF | DATE | TM | OPP | RESULT | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Mutuals | -25 | 5/13/1876 |  NYM | @ | HAR | L 3-28 | 3 | ||||||||||||||||||||||
| 2 | Bisons | -24 | 5/27/1885 | BUF | @ |  NYG | L 0-24 | 0 | |||||||||||||||||||||||
| 3 |  | Athletics | -23 | 5/24/1936 |  PHA | vs |  NYY | L 2-25 | 33 | 2 | 7 | 1 | 0 | 0 | 1 | 3 | 0 | 3 | 0 | 0 | 36 | 8 | 1 | 0 | .212 | .278 | .242 | .520 | |||
| 4 |  | Tigers | -22 | 5/18/1912 |  DET | @ | PHA | L 2-24 | 29 | 2 | 4 | 0 | 2 | 0 | 0 | 2 | 2 | 15 | 0 | 33 | 8 | 2 | 0 | .138 | .242 | .276 | .518 | ||||
| 5 |  | Phillies | -22 | 5/13/1902 |  PHN | @ |  CIN | L 2-24 | 34 | 2 | 8 | 0 | 0 | 0 | 1 | 1 | 0 | 2 | 0 | -13 | 35 | 8 | 0 | 0 | -13 | -13 | .235 | .257 | .235 | .492 | |
| 6 | Wolverines | -22 | 5/14/1884 | DET | @ | PRO | L 3-25 | 3 | |||||||||||||||||||||||
| 7 |  | Rockies | -21 | 5/10/2025 |  COL | vs |  SDP | L 0-21 | 30 | 0 | 5 | 1 | 0 | 0 | 0 | 2 | 0 | 7 | 0 | 0 | 32 | 6 | 1 | 0 | 0 | 0 | 2 | .167 | .219 | .200 | .419 |
| 8 | Solons | -21 | 5/7/1889 | COL | @ | STL | L 0-21 | 0 | |||||||||||||||||||||||
| 9 | | Tigers | -20 | 5/2/1939 | DET | vs | NYY | L 2-22 | 33 | 2 | 7 | 3 | 0 | 0 | 2 | 4 | 0 | 1 | 0 | 0 | 37 | 10 | 3 | 0 | 1 | .212 | .297 | .303 | .600 | ||
| 10 |  | Browns | -20 | 5/31/1897 |  STL | @ |  BSN | L 5-25 | 5 | ||||||||||||||||||||||
| 11 |  | Senators | -20 | 5/24/1892 |  WSH | @ |  BKN | L 4-24 | 4 | ||||||||||||||||||||||
| 12 | Burghers | -20 | 5/31/1890 | PTP | @ |  NYP | L 3-23 | 3 | |||||||||||||||||||||||
| 13 |  | Nationals | -20 | 5/6/1889 |  WSH | vs |  BSN | L 3-23 | 3 | ||||||||||||||||||||||
| 14 | Hoosiers | -20 | 5/17/1887 | IND | @ | NYG | L 6-26 | 6 | |||||||||||||||||||||||
| 15 | | Nationals | -20 | 5/28/1886 | WSH | vs |  CWS | L 0-20 | 0 | ||||||||||||||||||||||
| 16 | Bisons | -20 | 5/15/1884 | BUF | @ | PHN | L 5-25 | 5 | |||||||||||||||||||||||
| 17 |  | Nationals | -20 | 5/8/1884 |  WSU | @ | SLU | L 2-22 | 2 | ||||||||||||||||||||||
| 18 |  | Rays | -19 | 5/23/2023 |  TBR | vs |  TOR | L 1-20 | 30 | 1 | 6 | 2 | 0 | 1 | 1 | 3 | 1 | 5 | 0 | 0 | 34 | 11 | 3 | 0 | 0 | 0 | 2 | .200 | .294 | .367 | .661 |
| 19 |  | Pirates | -19 | 5/21/2021 |  PIT | @ | ATL | L 1-20 | 37 | 1 | 11 | 0 | 0 | 0 | 1 | 1 | 0 | 9 | 0 | 0 | 38 | 11 | 0 | 0 | 0 | 0 | 0 | .297 | .316 | .297 | .613 |
| 20 |  | White Sox | -19 | 5/21/2009 |  CWS | vs |  MIN | L 1-20 | 34 | 1 | 8 | 0 | 0 | 0 | 1 | 3 | 0 | 3 | 0 | 1 | 37 | 8 | 0 | 0 | 0 | 0 | 0 | .235 | .297 | .235 | .533 |
| 21 | | White Sox | -19 | 5/10/2002 | CWS | @ |  ANA | L 0-19 | 28 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 0 | 1 | 30 | 3 | 0 | 0 | 0 | 0 | 1 | .107 | .167 | .107 | .274 |
| 22 |  | Dodgers | -19 | 5/5/2001 | LAD | @ | CHC | L 1-20 | 31 | 1 | 6 | 1 | 0 | 0 | 1 | 3 | 0 | 8 | 0 | 0 | 34 | 7 | 1 | 0 | 0 | 0 | 2 | .194 | .265 | .226 | .491 |
| 23 |  | Red Sox | -19 | 5/20/1994 |  BOS | @ | MIN | L 2-21 | 31 | 2 | 6 | 1 | 0 | 1 | 2 | 1 | 0 | 1 | 0 | 0 | 32 | 10 | 2 | 0 | 0 | 0 | 2 | .194 | .219 | .323 | .541 |
| 24 |  | Padres | -19 | 5/13/1969 |  SDP | @ |  CHC | L 0-19 | 29 | 0 | 3 | 1 | 0 | 0 | 0 | 4 | 0 | 10 | 0 | 1 | 33 | 4 | 1 | 0 | 0 | 0 | 0 | .103 | .212 | .138 | .350 |
| 25 |  | Red Sox | -19 | 5/18/1955 |  BOS | vs |  CLE | L 0-19 | 30 | 0 | 3 | 1 | 0 | 0 | 0 | 3 | 0 | 9 | 0 | 0 | 33 | 4 | 1 | 0 | 0 | 0 | 0 | .100 | .182 | .133 | .315 |
Some of the information used here was obtained free of charge from Retrosheet.
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