mlb team most run differential this season before september 22 2025

The Milwaukee Brewers had the highest run differential by a team in 2025, with a differential of 181 runs.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Brewers	181	2025	156	.609	95	61	5,311	790	1,385	256	18	163	734	539	69	1,213	159	52	5,994	2,166	437	25	50	14	92	.261	.334	.408	.742
2	Yankees	144	2025	156	.564	88	68	5,282	816	1,320	249	19	263	788	609	53	1,408	132	35	6,004	2,396	531	7	53	43	101	.250	.330	.454	.784
3	Dodgers	126	2025	156	.564	88	68	5,268	794	1,336	249	19	232	761	565	55	1,294	86	24	5,954	2,319	500	13	53	33	106	.254	.329	.440	.769
4	Cubs	125	2025	156	.564	88	68	5,294	750	1,316	257	27	209	731	536	45	1,222	155	35	5,938	2,254	493	9	54	15	69	.249	.320	.426	.746
5	Phillies	122	2025	156	.590	92	64	5,314	756	1,381	263	24	200	731	516	60	1,271	120	29	5,945	2,292	487	15	40	18	92	.260	.330	.431	.761
6	Red Sox	105	2025	156	.545	85	71	5,363	765	1,365	309	23	182	727	504	71	1,364	137	38	5,991	2,266	514	13	40	24	93	.255	.325	.423	.747
7	Rangers	82	2025	156	.506	79	77	5,243	662	1,238	237	15	170	638	478	60	1,269	132	31	5,831	2,015	422	10	40	18	91	.236	.305	.384	.689
8	Tigers	73	2025	156	.545	85	71	5,257	743	1,302	239	36	193	709	491	64	1,384	60	15	5,866	2,192	468	5	49	12	85	.248	.317	.417	.734
9	Mariners	68	2025	156	.558	87	69	5,305	741	1,297	225	9	230	710	525	82	1,375	153	37	5,972	2,230	464	23	37	26	101	.244	.320	.420	.740
10	Blue Jays	66	2025	156	.577	90	66	5,318	768	1,418	284	11	182	741	500	63	1,054	74	24	5,959	2,270	477	34	44	25	129	.267	.334	.427	.761
11	Padres	60	2025	156	.545	85	71	5,219	665	1,316	248	18	142	627	489	57	1,113	105	29	5,855	2,026	408	46	44	16	102	.252	.321	.388	.709
12	Mets	56	2025	156	.513	80	76	5,254	739	1,315	255	19	215	720	542	86	1,274	140	18	5,949	2,253	489	14	53	28	117	.250	.327	.429	.756
13	Rays	49	2025	156	.487	76	80	5,264	696	1,324	235	16	177	663	451	45	1,340	188	48	5,818	2,122	428	16	42	10	104	.252	.314	.403	.717
14	Reds	34	2025	156	.513	80	76	5,243	697	1,284	243	23	161	659	508	49	1,353	104	30	5,854	2,056	427	12	42	15	99	.245	.315	.392	.707
15	Diamondbacks	29	2025	156	.506	79	77	5,280	773	1,330	268	37	209	752	520	79	1,252	117	37	5,975	2,299	514	35	61	19	104	.252	.325	.435	.760
16	Astros	17	2025	156	.538	84	72	5,287	659	1,328	237	12	172	629	454	67	1,248	78	26	5,861	2,105	421	16	37	15	121	.251	.316	.398	.714
17	Giants	14	2025	156	.494	77	79	5,181	674	1,214	230	26	164	644	534	64	1,339	66	22	5,850	1,988	420	22	49	13	103	.234	.311	.384	.695
18	Royals	-2	2025	156	.500	78	78	5,218	616	1,287	277	22	153	606	414	66	1,049	105	41	5,767	2,067	452	29	40	18	94	.247	.308	.396	.704
19	Guardians	-9	2025	156	.538	84	72	5,119	616	1,157	231	17	163	595	477	58	1,289	122	33	5,728	1,911	411	26	48	29	77	.226	.297	.373	.670
20	Braves	-11	2025	156	.468	73	83	5,315	699	1,304	236	18	180	677	548	49	1,317	77	24	5,962	2,116	434	15	35	14	95	.245	.320	.398	.718
21	Cardinals	-49	2025	156	.487	76	80	5,229	667	1,281	248	8	143	633	462	88	1,257	85	25	5,841	1,974	399	23	39	16	111	.245	.315	.378	.692
22	Pirates	-69	2025	156	.429	67	89	5,167	561	1,195	233	21	112	540	515	51	1,364	112	34	5,778	1,806	366	13	32	19	118	.231	.305	.350	.655
23	Athletics	-80	2025	156	.468	73	83	5,347	709	1,353	281	16	214	686	483	43	1,350	79	27	5,924	2,308	511	17	34	14	114	.253	.318	.432	.750
24	Marlins	-82	2025	156	.487	76	80	5,349	692	1,348	267	27	151	661	468	49	1,203	131	41	5,928	2,122	445	19	43	13	92	.252	.316	.397	.712
25	White Sox	-93	2025	156	.372	58	98	5,171	618	1,201	234	10	156	597	486	47	1,313	82	21	5,758	1,923	400	21	33	8	107	.232	.302	.372	.674