The Louisville Colonels have allowed the most runs by a team in a game, with 36 runs versus the Chicago Colts on June 29, 1897.
Interpreted as:
MLB team to allow the most runs in first inning of regular-season games| TEAM | R | DATE | TM | OPP | RESULT | ERA | SO | SHO | SV | IP | H | ER | HR | BB | HBP | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Colonels | 36 | 6/29/1897 | LOU | @ |  CHI | L 7-36 | ||||||||||||||||||||||||
| 2 | Blues | 35 | 7/24/1882 | CLE | @ | CWS | L 4-35 | ||||||||||||||||||||||||
| 3 | Bisons | 31 | 7/3/1883 | BUF | @ | CWS | L 7-31 | ||||||||||||||||||||||||
| 4 |  | Orioles | 30 | 8/22/2007 |  BAL | vs |  TEX | L 3-30 | 30.00 | 11 | 0 | 0 | 9.0 | 29 | 30 | 6 | 8 | 0 | 0 | 65 | 1 | 11.00 | 8.00 | 1.38 | 6.00 | 16.9 | 12.3 | 4.11 | .575 | 30.00 | 29.00 |
| 5 | Colonels | 30 | 6/18/1893 | LOU | @ |  CIN | L 12-30 | ||||||||||||||||||||||||
| 6 |  | Senators | 30 | 9/10/1891 |  WSH | @ |  MIL | L 3-30 | |||||||||||||||||||||||
| 7 | Bisons | 30 | 6/26/1890 | BUF | vs | PHP | L 12-30 | ||||||||||||||||||||||||
| 8 | Wolverines | 30 | 6/9/1883 | DET | @ |  BSN | L 8-30 | ||||||||||||||||||||||||
| 9 | Grays | 30 | 7/22/1876 | LOU | @ | CWS | L 7-30 | ||||||||||||||||||||||||
| 10 |  | Marlins | 29 | 9/9/2020 |  MIA | @ | ATL | L 9-29 | 30.38 | 9 | 0 | 0 | 8.0 | 23 | 27 | 7 | 9 | 1 | 0 | 58 | 0 | 10.13 | 10.13 | 1.00 | 7.88 | 15.5 | 15.5 | 4.00 | .500 | 32.63 | 25.88 |
| 11 |  | Athletics | 29 | 4/23/1955 |  KCA | vs |  CWS | L 6-29 | 27.00 | 4 | 0 | 0 | 9.0 | 29 | 27 | 7 | 6 | 1 | 1 | 63 | 1 | 4.00 | 6.00 | 0.67 | 7.00 | 6.3 | 9.5 | 3.89 | .489 | 29.00 | 29.00 |
| 12 |  | Browns | 29 | 6/8/1950 |  SLA | @ |  BSA | L 4-29 | 29.25 | 2 | 0 | 0 | 8.0 | 28 | 26 | 7 | 11 | 0 | 0 | 64 | 0 | 2.25 | 12.38 | 0.18 | 7.88 | 3.1 | 17.2 | 4.88 | .477 | 32.63 | 31.50 |
| 13 | Colonels | 29 | 8/17/1894 | LOU | @ |  PHI | L 4-29 | ||||||||||||||||||||||||
| 14 |  | Quakers | 29 | 6/15/1887 | PHN | @ |  NYG | L 1-29 | |||||||||||||||||||||||
| 15 | | Quakers | 29 | 6/20/1883 | PHN | @ | BSN | L 4-29 | |||||||||||||||||||||||
| 16 |  | Red Sox | 28 | 7/22/2022 |  BOS | vs |  TOR | L 5-28 | 27.00 | 9 | 0 | 0 | 9.0 | 29 | 27 | 5 | 5 | 1 | 0 | 63 | 2 | 9.00 | 5.00 | 1.80 | 5.00 | 14.3 | 7.9 | 3.78 | .558 | 28.00 | 29.00 |
| 17 | | Phillies | 28 | 7/6/1929 | PHN | vs |  SLN | L 6-28 | 0.00 | 1 | 0 | 0 | 9.0 | 28 | 0 | 2 | 9 | 1 | 65 | 0 | 1.00 | 9.00 | 0.11 | 2.00 | 1.5 | 13.8 | 4.11 | .500 | 28.00 | 28.00 | |
| 18 |  | Browns | 28 | 9/3/1896 | STL | @ |  BSN | L 7-28 | |||||||||||||||||||||||
| 19 |  | Grooms | 28 | 8/25/1891 |  BKN | @ | CHI | L 5-28 | |||||||||||||||||||||||
| 20 | Bisons | 28 | 7/12/1890 | BUF | @ | BKP | L 16-28 | ||||||||||||||||||||||||
| 21 | Spiders | 28 | 4/23/1888 | CLE | @ |  PHA | L 7-28 | ||||||||||||||||||||||||
| 22 |  | Alleghenys | 28 | 8/27/1887 |  PIT | @ | BSN | L 14-28 | |||||||||||||||||||||||
| 23 | Spiders | 28 | 4/30/1887 | CLE | @ | STL | L 11-28 | ||||||||||||||||||||||||
| 24 | | Quakers | 28 | 8/21/1883 | PHN | @ | PRO | L 0-28 | |||||||||||||||||||||||
| 25 |  | Mutuals | 28 | 5/13/1876 |  NYM | @ | HAR | L 3-28 | |||||||||||||||||||||||
Results may be incomplete. StatMuse has complete team, game-level data for runs allowed going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
Mets 
Yankees 
Tigers 
Twins 
Astros 
Angels 
CLE 
MIL 
TBR 
KCR 
