Pete Rose has gotten the most career hits by a player older than 22, with 4,086 hits.

Interpreted as:

most career hits by a player after age 22

	NAME	H	G	AB	R	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Pete Rose P. Rose	4,086	3,404	13,426	2,064	721	126	154	1,273	1,511	102	1,071	185	133	15,162	5,521	1,001	50	73	167	241	.304	.377	.411	.788
2	Ty Cobb T. Cobb	3,424	2,439	9,173	1,880	605	246	97		1,135	74		705		10,612	4,812	948	230				.373	.446	.525	.971
3	Hank Aaron H. Aaron	3,251	2,870	10,685	1,905	526	69	689	2,030	1,289	24	1,227	233	66	12,107	5,982	1,284	3	106	282	276	.304	.377	.560	.937
4	Stan Musial S. Musial	3,243	2,717	9,840	1,746	642	147	451	1,791	1,469	49	654	62	31	11,433	5,532	1,240	22	53	127	229	.330	.417	.562	.979
5	Derek Jeter D. Jeter	3,187	2,501	10,262	1,763	503	53	246	1,193	994	155	1,662	334	86	11,544	4,534	802	86	47	38	269	.311	.378	.442	.820
6	Paul Waner P. Waner	3,152	2,549	9,460	1,627	605	191	113	1,316	1,092	38	376	104		10,765	4,478	909	175			45	.333	.404	.473	.878
7	Tristram Speaker T. Speaker	3,135	2,470	8,980	1,704	746	192	103		1,293	90		364		10,644	4,574	1,041	281				.349	.436	.509	.945
8	Carl Yastrzemski C. Yastrzemski	3,115	3,034	10,902	1,672	584	47	425	1,692	1,744	34	1,233	155	108	12,788	5,068	1,056	9	99	182	283	.286	.383	.465	.848
9	Willie Mays W. Mays	3,107	2,818	10,212	1,979	498	129	633	1,803	1,392	41	1,443	327	97	11,747	5,762	1,260	12	90	193	237	.304	.387	.564	.951
10	Ichiro Suzuki I. Suzuki	3,089	2,653	9,934	1,420	362	96	117	780	647	55	1,080	509	117	10,734	3,994	575	50	48	181	92	.311	.355	.402	.757
11	Tony Gwynn T. Gwynn	3,086	2,386	9,098	1,350	531	83	134	1,121	776	24	418	311	122	10,023	4,185	748	41	84	203	254	.339	.389	.460	.849
12	Paul Molitor P. Molitor	3,036	2,448	9,865	1,646	557	97	221	1,213	1,040	42	1,158	449	110	11,108	4,450	875	62	99	95	194	.308	.373	.451	.824
13	Craig Biggio C. Biggio	3,034	2,800	10,753	1,830	662	54	288	1,170	1,153	285	1,724	408	123	12,372	4,668	1,004	100	81	66	149	.282	.364	.434	.799
14	Wade Boggs W. Boggs	3,010	2,439	9,180	1,513	578	61	118	1,014	1,412	23	745	24	35	10,740	4,064	757	29	96	180	236	.328	.415	.443	.858
15	Albert Pujols A. Pujols	3,005	2,762	10,241	1,684	599	10	632	1,961	1,232	105	1,242	114	36	11,690	5,520	1,241	0	112	297	385	.293	.371	.539	.910
16	Eddie Collins E. Collins	3,002	2,540	8,969	1,668	389	169	42		1,444	68		664		10,956	3,855	600	475				.335	.431	.430	.860
17	Sam Rice S. Rice	2,986	2,405	9,275	1,514	498	184	34		709	57	274	352		10,252	3,954	716	211				.322	.374	.426	.800
18	Lou Brock L. Brock	2,960	2,551	10,087	1,567	470	136	142	879	743	46	1,676	930	304	10,967	4,128	748	47	44	124	112	.293	.343	.409	.753
19	Rafael Palmeiro R. Palmeiro	2,953	2,735	10,208	1,630	569	37	556	1,798	1,333	86	1,317	94	38	11,759	5,264	1,162	15	117	171	224	.289	.372	.516	.888
20	Dave Winfield D. Winfield	2,939	2,772	10,364	1,603	518	83	442	1,746	1,164	24	1,571	214	89	11,660	4,949	1,043	19	89	169	300	.284	.355	.478	.832
21	Eddie Murray E. Murray	2,908	2,705	10,115	1,461	499	30	450	1,734	1,215	16	1,315	104	37	11,461	4,817	979	1	114	209	278	.287	.361	.476	.837
22	Cal Ripken Jr. C. Ripken Jr.	2,879	2,697	10,431	1,476	537	37	386	1,530	1,032	63	1,127	33	33	11,651	4,648	960	8	117	104	310	.276	.341	.446	.787
23	Charlie Gehringer C. Gehringer	2,820	2,294	8,778	1,763	572	145	184	1,427	1,186	50	362	180		10,149	4,234	901	135			27	.321	.405	.482	.887
24	Omar Vizquel O. Vizquel	2,792	2,825	10,199	1,400	449	74	79	931	1,000	48	1,047	403	163	11,582	3,626	602	243	92	25	201	.274	.339	.356	.694
25	George Brett G. Brett	2,789	2,378	9,125	1,430	603	118	303	1,450	1,020	31	809	178	78	10,296	4,537	1,024	9	111	218	216	.306	.373	.497	.870