Before 2012, Reggie Jackson had the most strikeouts, with 2,597 strikeouts.

Interpreted as:

most career strikeouts by a player through 2011

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Reggie Jackson R. Jackson	2,597	2,820	9,864	1,551	2,584	463	49	563	1,702	1,375	96	228	115	11,416	4,834	1,075	13	68	164	183	.262	.356	.490	.846	1749	503	.374	139	497.6
2	Jim Thome J. Thome	2,487	2,485	8,259	1,566	2,287	444	26	604	1,674	1,725	68	19	20	10,127	4,595	1,074	1	74	170	159	.277	.403	.556	.959	1900	650.3	.407	145	586.9
3	Sammy Sosa S. Sosa	2,306	2,354	8,813	1,475	2,408	379	45	609	1,667	929	59	234	107	9,896	4,704	1,033	17	78	154	202	.273	.344	.534	.878	1559	345.1	.370	124	307.3
4	Andres Galarraga A. Galarraga	2,003	2,257	8,096	1,195	2,333	444	32	399	1,425	583	178	128	81	8,916	4,038	875	1	58	106	179	.288	.347	.499	.846	1355	286.5	.365	118	193.8
5	Jose Canseco J. Canseco	1,942	1,887	7,057	1,186	1,877	340	14	462	1,407	906	84	200	88	8,129	3,631	816	1	81	63	178	.266	.353	.515	.867	1293	321.2	.375	130	300.8
6	Willie Stargell W. Stargell	1,936	2,360	7,927	1,194	2,232	423	55	475	1,540	937	78	17	16	9,026	4,190	953	9	75	227	143	.282	.360	.529	.889	1471	511.5	.387	145	459.3
7	Alex Rodriguez A. Rodriguez	1,916	2,402	9,199	1,824	2,775	495	29	629	1,893	1,166	157	305	73	10,634	5,215	1,153	16	96	88	222	.302	.386	.567	.953	1972	663	.404	145	610.2
8	Mike Cameron M. Cameron	1,901	1,955	6,839	1,064	1,700	383	59	278	968	867	87	297	83	7,884	3,035	720	31	60	19	114	.249	.338	.444	.782	1043	70.3	.341	107	69.2
9	Mike Schmidt M. Schmidt	1,883	2,404	8,352	1,506	2,234	408	59	548	1,595	1,507	79	174	92	10,062	4,404	1,015	16	108	201	156	.267	.380	.527	.908	1717	591	.395	147	539.8
10	Fred McGriff F. McGriff	1,882	2,460	8,757	1,349	2,490	441	24	493	1,550	1,305	39	72	38	10,174	4,458	958	2	71	171	226	.284	.377	.509	.886	1678	454.1	.383	134	415.9
11	Tony Perez T. Perez	1,867	2,777	9,778	1,272	2,732	505	79	379	1,652	925	43	49	33	10,861	4,532	963	9	106	150	268	.279	.341	.463	.804	1511	343.8	.356	121	265.2
12	Dave Kingman D. Kingman	1,816	1,941	6,677	901	1,575	240	25	442	1,210	608	53	85	49	7,429	3,191	707	16	75	72	139	.236	.302	.478	.780	960	139.8	.343	113	108.5
13	Manny Ramirez M. Ramirez	1,813	2,302	8,244	1,544	2,574	547	20	555	1,831	1,329	109	38	33	9,774	4,826	1,122	2	90	216	243	.312	.411	.585	.996	1931	719.5	.418	153	658.7
14	Adam Dunn A. Dunn	1,809	1,570	5,390	901	1,312	282	10	365	922	1,065	75	59	22	6,561	2,709	657	2	29	107	85	.243	.374	.503	.876	1056	264	.375	126	216.1
15	Ken Griffey Jr. K. Griffey Jr.	1,779	2,671	9,801	1,662	2,781	524	38	630	1,836	1,312	81	184	69	11,304	5,271	1,192	8	102	246	199	.284	.370	.538	.907	1892	521.1	.384	132	453.4
16	Bobby Abreu B. Abreu	1,763	2,247	8,128	1,412	2,384	554	58	284	1,325	1,419	33	393	126	9,669	3,906	896	7	82	112	155	.293	.397	.481	.878	1603	418.9	.381	131	383.1
17	Bobby Bonds B. Bonds	1,757	1,849	7,043	1,258	1,886	302	66	332	1,024	914	53	461	169	8,090	3,316	700	16	64	75	107	.268	.353	.471	.824	1192	318.7	.368	130	274.9
18	Craig Biggio C. Biggio	1,753	2,850	10,876	1,844	3,060	668	55	291	1,175	1,160	285	414	124	12,503	4,711	1,014	101	81	68	150	.281	.363	.433	.796	1768	248.9	.352	115	238.9
19	Dale Murphy D. Murphy	1,748	2,180	7,960	1,197	2,111	350	39	398	1,266	986	28	161	68	9,040	3,733	787	6	60	159	209	.265	.346	.469	.815	1291	273.7	.357	119	202.4
20	Carlos Delgado C. Delgado	1,745	2,035	7,283	1,241	2,038	483	18	473	1,512	1,109	172	14	8	8,657	3,976	974	0	93	186	152	.280	.383	.546	.929	1513	435.7	.391	135	394
21	Lou Brock L. Brock	1,730	2,616	10,332	1,610	3,023	486	141	149	900	761	49	938	307	11,235	4,238	776	47	46	124	114	.293	.343	.410	.753	1406	210.2	.336	109	113.1
22	Jim Edmonds J. Edmonds	1,729	2,011	6,858	1,251	1,949	437	25	393	1,199	998	49	67	50	7,980	3,615	855	10	65	91	122	.284	.376	.527	.903	1352	362.4	.385	132	326.3
23	Mickey Mantle M. Mantle	1,710	2,401	8,102	1,676	2,415	344	72	536	1,509	1,733	13	153	38	9,909	4,511	952	14	47	126	113	.298	.421	.557	.977	1941	840	.428	170	821.8
24	Harmon Killebrew H. Killebrew	1,699	2,435	8,147	1,283	2,086	290	24	573	1,584	1,559	48	19	18	9,831	4,143	887	0	77	160	243	.256	.376	.509	.884	1630	569	.389	142	477.8
25	Chili Davis C. Davis	1,698	2,435	8,673	1,240	2,380	424	30	350	1,372	1,194	15	142	98	9,996	3,914	804	20	94	188	232	.274	.360	.451	.811	1420	249.9	.354	118	225.1