Jesse Orosco has thrown in the most career games by a relief pitcher, with 1,248 games.

Interpreted as:

most regular-season g by a relief pitcher

	NAME	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Jesse Orosco J. Orosco	1,248	87	78	.527	0	3.12	1,169	0	0	144	1277.0	1,035	442	499	112	568	34	501	85	5,374	40	8.24	4.00	2.06	0.79	21.8	10.6	1.26	.264	3.52	7.29
2	Mike Stanton M. Stanton	1,177	68	63	.519	0	3.93	892	0	0	84	1110.0	1,084	485	523	93	419	33	363	76	4,748	35	7.23	3.40	2.13	0.75	18.8	8.8	1.35	.299	4.24	8.79
3	John Franco J. Franco	1,119	90	87	.508	0	2.89	975	0	0	424	1245.2	1,166	400	466	81	495	22	774	78	5,312	54	7.04	3.58	1.97	0.59	18.4	9.3	1.33	.290	3.37	8.42
4	Mariano Rivera M. Rivera	1,105	79	57	.581	0	2.06	1,135	0	0	652	1233.2	934	282	305	63	266	44	952	41	4,870	13	8.28	1.94	4.27	0.46	23.3	5.5	0.97	.259	2.23	6.81
5	Mike Timlin M. Timlin	1,054	74	71	.510	0	3.64	859	0	0	141	1185.1	1,148	479	526	118	369	47	467	72	4,999	31	6.52	2.80	2.33	0.90	17.2	7.4	1.28	.286	3.99	8.72
6	Dan Plesac D. Plesac	1,050	62	67	.481	0	3.55	990	0	0	158	1003.0	907	396	439	98	370	14	422	52	4,229	41	8.88	3.32	2.68	0.88	23.4	8.7	1.27	.293	3.94	8.14
7	Kent Tekulve K. Tekulve	1,050	94	90	.511	0	2.85	779	0	0	184	1436.2	1,305	455	526	63	491	17	638	179	6,001	23	4.88	3.08	1.59	0.39	13.0	8.2	1.25	.267	3.30	8.18
8	Trevor Hoffman T. Hoffman	1,035	61	75	.449	0	2.87	1,133	0	0	601	1089.1	846	347	378	100	307	9	856	58	4,388	49	9.36	2.54	3.69	0.83	25.8	7.0	1.06	.263	3.12	6.99
9	Hoyt Wilhelm H. Wilhelm	1,018	124	103	.546	0	2.49	1,363	0	0	228	1872.1	1,436	518	636	125	661	51	651	58	7,619	83	6.55	3.18	2.06	0.60	17.9	8.7	1.12	.242	3.06	6.90
10	Lee Smith L. Smith	1,016	71	87	.449	0	2.98	1,225	0	0	478	1252.1	1,095	415	456	87	474	9	802	100	5,230	46	8.80	3.41	2.58	0.63	23.4	9.1	1.25	.293	3.28	7.87
11	Roberto Hernandez R. Hernandez	1,007	66	71	.482	0	3.42	940	0	0	326	1060.0	992	403	465	95	457	35	667	53	4,583	49	7.98	3.88	2.06	0.81	20.5	10.0	1.37	.294	3.95	8.42
12	Michael Jackson M. Jackson	998	61	63	.492	0	3.33	983	0	0	142	1154.2	948	427	467	119	440	56	422	80	4,810	34	7.66	3.43	2.23	0.93	20.4	9.1	1.20	.258	3.64	7.39
13	Todd Jones T. Jones	981	58	62	.483	0	3.95	866	0	0	319	1067.2	1,063	468	513	93	443	38	619	62	4,629	43	7.30	3.73	1.95	0.78	18.7	9.6	1.41	.304	4.32	8.96
14	Rich Gossage R. Gossage	965	115	85	.575	0	2.77	1,340	0	0	310	1556.2	1,235	479	537	98	628	38	681	87	6,408	56	7.75	3.63	2.13	0.57	20.9	9.8	1.20	.264	3.10	7.14
15	Fernando Rodney F. Rodney	951	48	71	.403	0	3.80	943	0	0	327	933.0	817	394	433	73	464	52	590	38	4,064	65	9.10	4.48	2.03	0.70	23.2	11.4	1.37	.294	4.18	7.88
16	Francisco Rodriguez F. Rodriguez	948	52	53	.495	0	2.86	1,142	0	0	437	976.0	738	310	336	98	389	17	677	42	4,011	68	10.53	3.59	2.94	0.90	28.5	9.7	1.15	.271	3.10	6.81
17	LaTroy Hawkins L. Hawkins	944	49	50	.495	0	3.32	685	0	0	127	949.0	932	350	382	78	270	10	373	32	3,964	43	6.50	2.56	2.54	0.74	17.3	6.8	1.27	.292	3.62	8.84
18	Kenley Jansen K. Jansen	934	54	40	.574	0	2.57	1,278	0	0	475	927.1	610	265	284	88	282	32	700	20	3,680	21	12.40	2.74	4.53	0.85	34.7	7.7	0.96	.261	2.76	5.92
19	Jose Mesa J. Mesa	927	53	69	.434	0	3.95	753	0	0	321	984.0	1,007	432	475	96	419	40	633	51	4,321	58	6.89	3.83	1.80	0.88	17.4	9.7	1.45	.302	4.34	9.21
20	Gene Garber G. Garber	922	94	108	.465	0	3.30	913	0	0	218	1452.2	1,404	533	624	113	424	37	609	151	6,083	29	5.66	2.63	2.15	0.70	15.0	7.0	1.26	.281	3.87	8.70
21	Lindy McDaniel L. McDaniel	913	119	88	.575	0	3.14	1,165	0	0	174	1694.2	1,590	591	682	122	486	11	577	120	7,019	92	6.19	2.58	2.40	0.65	16.6	6.9	1.23	.280	3.62	8.44
22	Rollie Fingers R. Fingers	907	107	101	.514	0	2.73	1,183	0	0	341	1505.2	1,276	456	502	97	429	29	709	105	6,104	37	7.07	2.56	2.76	0.58	19.4	7.0	1.13	.270	3.00	7.63
23	Sparky Lyle S. Lyle	899	99	76	.566	0	2.88	873	0	0	238	1390.1	1,292	445	519	84	481	14	634	81	5,796	68	5.65	3.11	1.81	0.54	15.1	8.3	1.28	.278	3.36	8.36
24	David Weathers D. Weathers	895	55	61	.474	0	3.80	758	0	0	75	1018.0	986	430	468	102	445	44	304	65	4,427	23	6.70	3.93	1.70	0.90	17.1	10.1	1.41	.287	4.14	8.72
25	Mike Myers M. Myers	883	25	24	.510	0	4.29	429	0	0	14	541.2	525	258	278	58	256	43	195	33	2,385	10	7.13	4.25	1.68	0.96	18.0	10.7	1.44	.292	4.62	8.72