Between the 1920 and 1929 seasons, Eddie Rommel threw in the most games, with 424 games.

Interpreted as:

most regular-season games as a pitcher in the 1920s

	NAME	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Eddie Rommel E. Rommel	424	154	108	.588	230	3.47	530	132	17	25	2243.1	2,367	865	1,054	116	652	31	138	9,531	25	2.13	2.62	0.81	0.47	5.6	6.8	1.35	.274	4.23	82	4.11	98	9.50	21.7
2	Eppa Rixey E. Rixey	386	166	142	.539	330	3.24	686	185	20	10	2678.1	2,827	964	1,169	59	567	37	47	11,150	38	2.31	1.91	1.21	0.20	6.2	5.1	1.27	.282	3.93	85	3.44	89	9.50	117.2
3	Waite Hoyt W. Hoyt	379	161	102	.612	280	3.51	748	160	17	30	2346.0	2,464	914	1,080	88	669	33	80	9,964	25	2.87	2.57	1.12	0.34	7.5	6.7	1.34	.282	4.14	87	3.75	94	9.45	57.6
4	Bill Sherdel B. Sherdel	378	139	108	.563	209	3.70	657	128	10	24	2061.1	2,317	848	999	116	490	45	118	8,853	18	2.87	2.14	1.34	0.51	7.4	5.5	1.36	.292	4.36	93	3.86	97	10.12	28.7
5	Burleigh Grimes B. Grimes	373	190	130	.594	336	3.52	1,018	234	20	11	2797.2	2,988	1,093	1,354	105	842	62	31	12,039	51	3.27	2.71	1.21	0.34	8.5	7.0	1.37	.288	4.36	90	3.72	94	9.61	69.1
6	Jack Quinn J. Quinn	368	131	111	.541	251	3.50	575	124	19	22	2042.0	2,317	795	983	65	432	47	68	8,739	24	2.53	1.90	1.33	0.29	6.6	4.9	1.35	.296	4.33	85	3.54	86	10.21	126.3
7	Elam Vangilder E. Vangilder	364	98	102	.490	186	4.29	468	90	13	20	1702.2	1,879	812	1,010	93	697	42	118	7,516	21	2.47	3.68	0.67	0.49	6.2	9.3	1.51	.287	5.34	100	4.45	105	9.93	-28.2
8	Sad Sam Jones S. Sam Jones	363	137	118	.537	278	3.83	718	150	21	23	2230.0	2,345	948	1,137	85	791	36	59	9,559	37	2.90	3.19	0.91	0.34	7.5	8.3	1.41	.285	4.59	95	3.95	99	9.46	9.4
9	George Uhle G. Uhle	356	152	124	.551	285	3.97	808	182	16	16	2309.2	2,570	1,019	1,214	64	719	90	51	10,125	43	3.15	2.80	1.12	0.25	8.0	7.1	1.42	.297	4.73	95	3.72	90	10.01	112.1
10	Dolf Luque D. Luque	353	138	146	.486	302	3.09	904	168	21	8	2479.2	2,446	851	1,059	75	688	21	38	10,321	35	3.28	2.50	1.31	0.27	8.8	6.7	1.26	.275	3.84	82	3.52	93	8.88	74.3
11	Herb Pennock H. Pennock	352	163	112	.593	286	3.44	731	181	21	23	2313.0	2,485	883	1,038	87	556	21	48	9,743	28	2.84	2.16	1.31	0.34	7.5	5.7	1.31	.287	4.04	86	3.60	91	9.67	88.4
12	Slim Harriss S. Harriss	349	95	135	.413	229	4.25	644	89	7	17	1750.1	1,963	827	1,006	73	630	41	78	7,661	19	3.31	3.24	1.02	0.38	8.4	8.2	1.48	.301	5.17	102	3.94	95	10.09	41.9
13	Jesse Haines J. Haines	346	153	119	.563	293	3.61	742	169	20	5	2328.1	2,490	935	1,132	122	644	47	32	9,897	33	2.87	2.49	1.15	0.47	7.5	6.5	1.35	.284	4.38	92	3.92	99	9.62	3.6
14	Tom Zachary T. Zachary	336	128	122	.512	263	3.74	426	126	15	11	2018.1	2,313	838	1,017	77	609	33	50	8,685	24	1.90	2.72	0.70	0.34	4.9	7.0	1.45	.297	4.53	93	4.01	101	10.31	-12.9
15	Firpo Marberry F. Marberry	333	78	56	.582	70	3.44	453	36	1	72	1038.1	1,006	397	480	26	377	31	199	4,403	6	3.93	3.27	1.20	0.23	10.3	8.6	1.33	.279	4.16	85	3.66	91	8.72	43.9
16	Howard Ehmke H. Ehmke	333	136	137	.498	275	3.81	824	162	14	13	2265.0	2,319	959	1,151	89	805	118	43	9,783	17	3.27	3.20	1.02	0.35	8.4	8.2	1.38	.281	4.57	93	3.99	98	9.21	23.1
17	Urban Shocker U. Shocker	330	156	93	.627	261	3.34	753	168	22	22	2148.2	2,256	797	946	117	484	26	53	9,020	10	3.15	2.03	1.56	0.49	8.3	5.4	1.28	.280	3.96	80	3.71	90	9.45	102.2
18	Jack Scott J. Scott	329	96	101	.487	180	3.92	588	105	11	18	1666.1	1,819	726	839	91	446	39	113	7,134	22	3.18	2.41	1.32	0.49	8.2	6.3	1.36	.289	4.53	104	3.85	100	9.82	-4.3
19	Grover Alexander G. Alexander	325	165	105	.611	290	3.04	653	194	20	16	2415.1	2,528	816	982	111	349	15	29	9,893	18	2.43	1.30	1.87	0.41	6.6	3.5	1.19	.276	3.66	77	3.48	88	9.42	127
20	Red Faber R. Faber	316	149	116	.562	297	3.34	804	181	17	4	2364.0	2,429	878	1,045	73	664	47	14	9,958	28	3.06	2.53	1.21	0.28	8.1	6.7	1.31	.281	3.98	83	3.62	90	9.25	101.7
21	Art Nehf A. Nehf	312	123	77	.615	212	3.66	495	103	13	14	1720.0	1,853	699	821	92	425	16	69	7,234	18	2.59	2.22	1.16	0.48	6.8	5.9	1.32	.284	4.30	96	3.87	100	9.70	-7.7
22	Jimmy Ring J. Ring	312	96	128	.429	251	4.39	713	126	3	6	1944.0	2,181	948	1,172	96	819	23	34	8,652	81	3.30	3.79	0.87	0.44	8.2	9.5	1.54	.298	5.43	106	4.18	100	10.10	17.6
23	Hal Carlson H. Carlson	310	95	96	.497	197	4.19	454	102	15	18	1636.0	1,922	762	872	87	391	29	73	7,050	14	2.50	2.15	1.16	0.48	6.4	5.5	1.41	.301	4.80	103	3.89	95	10.57	42.2
24	Pete Donohue P. Donohue	308	126	107	.541	248	3.68	532	132	16	12	1962.0	2,210	803	969	57	376	43	45	8,355	10	2.44	1.72	1.41	0.26	6.4	4.5	1.32	.293	4.44	95	3.49	90	10.14	81.2
25	Carl Mays C. Mays	304	126	72	.636	200	3.44	409	132	14	19	1796.1	1,898	686	812	62	407	40	77	7,512	13	2.05	2.04	1.00	0.31	5.4	5.4	1.28	.278	4.07	87	3.72	95	9.51	38.6