Between the 1990 and 1999 seasons, Paul Assenmacher and Michael Jackson were tied for throwing in the most games, with 644 games.

Interpreted as:

most regular-season games as a pitcher in the 1990s

	NAME	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Paul Assenmacher P. Assenmacher	644	42	29	.592	1	3.51	562	0	0	42	576.2	552	225	242	53	205	19	189	51	2,466	19	8.77	3.20	2.74	0.83	22.8	8.3	1.31	.307	3.78	83	3.37	80	8.62	53.7
2	Michael Jackson M. Jackson	644	40	40	.500	0	3.22	639	0	0	126	696.1	546	249	269	65	257	34	309	49	2,867	21	8.26	3.32	2.49	0.84	22.3	9.0	1.15	.257	3.48	77	3.63	85	7.06	49.8
3	Doug Jones D. Jones	618	48	58	.453	4	3.47	618	0	0	223	779.0	800	300	327	70	169	27	483	36	3,273	14	7.14	1.95	3.66	0.81	18.9	5.2	1.24	.306	3.78	82	3.34	80	9.24	74.2
4	Dan Plesac D. Plesac	612	32	42	.432	14	4.14	582	0	0	54	633.0	616	291	316	67	242	12	207	38	2,717	22	8.27	3.44	2.40	0.95	21.4	8.9	1.36	.303	4.49	98	3.73	90	8.76	32.4
5	Jesse Orosco J. Orosco	594	31	22	.585	0	3.57	475	0	0	22	489.1	395	194	216	50	242	13	177	36	2,084	17	8.74	4.45	1.96	0.92	22.8	11.6	1.30	.265	3.97	81	3.96	90	7.26	24.3
6	Mike Stanton M. Stanton	591	35	28	.556	1	4.10	464	0	0	58	573.1	547	261	283	57	219	16	204	34	2,442	16	7.28	3.44	2.12	0.89	19.0	9.0	1.34	.291	4.44	95	3.94	91	8.59	25.3
7	Jeff Montgomery J. Montgomery	578	30	45	.400	0	3.42	579	0	0	285	694.2	640	264	291	70	232	22	491	34	2,914	23	7.50	3.01	2.50	0.91	19.9	8.0	1.26	.283	3.77	75	3.72	85	8.29	48.1
8	Eric Plunk E. Plunk	557	49	37	.570	8	3.62	729	0	0	27	753.1	683	303	339	84	380	23	182	34	3,285	47	8.71	4.54	1.92	1.00	22.2	11.6	1.41	.290	4.05	82	4.12	95	8.16	22.5
9	Scott Radinsky S. Radinsky	554	42	25	.627	0	3.34	355	0	0	52	479.2	457	178	202	31	205	12	180	29	2,077	8	6.66	3.85	1.73	0.58	17.1	9.9	1.38	.289	3.79	82	3.71	89	8.57	23.9
10	Rick Aguilera R. Aguilera	553	45	47	.489	19	3.51	584	2	0	282	695.0	640	271	297	82	179	16	489	29	2,870	28	7.56	2.32	3.26	1.06	20.3	6.2	1.18	.278	3.85	76	3.72	83	8.29	55.6
11	Chuck McElroy C. McElroy	551	33	27	.550	0	3.67	499	0	0	17	590.2	565	241	275	45	278	7	159	37	2,548	19	7.60	4.24	1.79	0.69	19.6	10.9	1.43	.303	4.19	85	3.76	88	8.61	34
12	Randy Myers R. Myers	543	27	50	.351	12	3.36	620	1	0	291	644.2	579	241	259	53	299	9	433	31	2,760	24	8.66	4.17	2.07	0.74	22.5	10.8	1.36	.296	3.62	83	3.54	86	8.08	43.6
13	Rod Beck R. Beck	540	26	37	.413	0	3.20	499	0	0	260	587.1	540	209	226	68	131	14	443	24	2,411	16	7.65	2.01	3.81	1.04	20.7	5.4	1.14	.278	3.46	80	3.57	86	8.27	33.9
14	Dennis Eckersley D. Eckersley	530	32	33	.492	0	3.18	536	0	0	293	543.2	492	192	210	58	83	14	437	21	2,191	3	8.87	1.37	6.46	0.96	24.5	3.8	1.06	.289	3.48	76	2.92	69	8.14	77.4
15	Mel Rojas M. Rojas	525	34	31	.523	0	3.82	562	0	0	126	667.0	591	283	305	65	254	37	282	31	2,830	30	7.58	3.43	2.21	0.88	19.9	9.0	1.27	.275	4.12	93	3.90	97	7.97	7.7
16	John Wetteland J. Wetteland	525	37	32	.536	5	2.66	655	0	0	295	602.1	468	178	206	55	194	14	459	24	2,465	24	9.79	2.90	3.38	0.82	26.6	7.9	1.10	.267	3.08	62	3.08	72	6.99	81.9
17	Stan Belinda S. Belinda	521	40	33	.548	0	3.85	561	0	0	78	628.1	522	269	284	71	261	31	244	38	2,652	22	8.04	3.74	2.15	1.02	21.2	9.8	1.25	.261	4.07	92	4.08	98	7.48	7.1
18	Bob Patterson B. Patterson	518	32	30	.516	6	3.64	415	0	0	27	507.1	485	205	216	60	142	8	167	30	2,098	7	7.36	2.52	2.92	1.06	19.8	6.8	1.24	.289	3.83	90	3.76	92	8.60	19.5
19	Roberto Hernandez R. Hernandez	512	38	35	.521	3	3.02	570	0	0	234	582.0	491	195	215	40	244	18	430	22	2,464	20	8.81	3.77	2.34	0.62	23.1	9.9	1.26	.283	3.32	67	3.34	75	7.59	73.8
20	Tony Fossas T. Fossas	511	15	22	.405	0	3.95	282	0	0	6	349.0	366	153	181	36	156	9	132	29	1,558	9	7.27	4.02	1.81	0.93	18.1	10.0	1.50	.307	4.67	92	4.15	98	9.44	3.3
21	Gregg Olson G. Olson	507	34	34	.500	0	3.47	450	0	0	190	533.2	484	206	219	36	247	10	372	29	2,281	33	7.59	4.17	1.82	0.61	19.7	10.8	1.37	.291	3.69	79	3.62	82	8.16	42.2
22	Jeff Shaw J. Shaw	496	28	45	.384	19	3.48	448	0	0	133	716.0	697	277	307	74	200	22	267	33	2,997	18	5.63	2.51	2.24	0.93	14.9	6.7	1.25	.277	3.86	84	4.07	98	8.76	9.9
23	Mark Guthrie M. Guthrie	489	33	36	.478	35	4.10	557	3	1	12	707.0	729	322	360	70	262	11	117	35	3,040	39	7.09	3.34	2.13	0.89	18.3	8.6	1.40	.308	4.58	96	3.85	92	9.28	25.6
24	John Franco J. Franco	485	35	40	.467	0	2.81	434	0	0	268	513.1	501	160	191	29	194	10	425	23	2,213	29	7.61	3.40	2.24	0.51	19.6	8.8	1.35	.305	3.35	71	3.25	81	8.78	45.3
25	Rich Rodriguez R. Rodriguez	485	26	17	.605	2	3.47	332	0	0	7	544.1	524	210	229	52	217	6	119	42	2,304	17	5.49	3.59	1.53	0.86	14.4	9.4	1.36	.278	3.79	87	4.23	104	8.66	-10.4