Nolan Ryan had the most games pitched when his Game Score was >5, with 773 games.

Interpreted as:

most regular-season games by a player with a game score above 5

	NAME	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Nolan Ryan N. Ryan	773	318	291	.522	773	3.18	5,654	222	61	0	5326.0	3,880	1,884	2,151	314	2,748	156	0	75	22,310	275	9.55	4.64	2.06	0.53	25.3	12.3	1.24	.265	3.63	6.56
2	Don Sutton D. Sutton	756	321	253	.559	756	3.27	3,545	178	58	0	5248.1	4,670	1,905	2,095	469	1,333	81	0	96	21,500	110	6.08	2.29	2.66	0.80	16.5	6.2	1.14	.261	3.59	8.01
3	Greg Maddux G. Maddux	739	355	225	.612	739	3.14	3,364	109	35	0	4998.2	4,706	1,742	1,966	350	996	137	0	177	20,371	69	6.06	1.79	3.38	0.63	16.5	4.9	1.14	.281	3.54	8.47
4	Phil Niekro P. Niekro	715	302	261	.536	715	3.36	3,181	245	45	0	5148.2	4,804	1,921	2,220	465	1,703	116	0	73	21,571	207	5.56	2.98	1.87	0.81	14.7	7.9	1.26	.269	3.88	8.40
5	Steve Carlton S. Carlton	708	327	239	.578	708	3.18	4,103	254	55	0	5160.2	4,605	1,826	2,087	404	1,810	53	0	145	21,428	176	7.16	3.16	2.27	0.70	19.1	8.4	1.24	.279	3.64	8.03
6	Roger Clemens R. Clemens	706	354	183	.659	706	3.11	4,671	118	46	0	4912.1	4,173	1,698	1,876	363	1,577	158	0	63	20,211	143	8.56	2.89	2.96	0.67	23.1	7.8	1.17	.283	3.44	7.65
7	Tommy John T. John	698	284	226	.557	698	3.32	2,189	162	46	0	4614.2	4,675	1,702	1,964	295	1,220	97	0	99	19,270	177	4.27	2.38	1.79	0.58	11.4	6.3	1.28	.283	3.83	9.12
8	Gaylord Perry G. Perry	689	305	251	.549	689	3.09	3,372	303	53	0	5154.1	4,751	1,770	2,037	382	1,314	101	0	144	21,122	149	5.89	2.29	2.57	0.67	16.0	6.2	1.18	.274	3.56	8.30
9	Bert Blyleven B. Blyleven	685	286	248	.536	685	3.31	3,694	242	60	0	4957.1	4,614	1,823	2,021	428	1,316	155	0	67	20,429	114	6.71	2.39	2.81	0.78	18.1	6.4	1.20	.282	3.67	8.38
10	Tom Glavine T. Glavine	680	305	201	.603	680	3.50	2,603	56	25	0	4406.1	4,276	1,716	1,882	355	1,495	65	0	144	18,557	64	5.32	3.05	1.74	0.73	14.0	8.1	1.31	.279	3.84	8.73
11	Warren Spahn W. Spahn	665	358	227	.612	665	3.08	2,501	382	63	0	5101.0	4,703	1,743	1,951	422	1,383	39	0	52	20,960	74	4.41	2.44	1.81	0.74	11.9	6.6	1.19	.258	3.44	8.30
12	Tom Seaver T. Seaver	647	310	203	.604	647	2.86	3,634	231	61	0	4776.1	3,961	1,517	1,670	378	1,387	76	0	115	19,337	123	6.85	2.61	2.62	0.71	18.8	7.2	1.12	.258	3.15	7.46
13	Jamie Moyer J. Moyer	635	262	203	.563	635	4.21	2,349	33	10	0	3937.1	4,075	1,842	1,990	502	1,097	141	0	64	16,743	50	5.37	2.51	2.14	1.15	14.0	6.6	1.31	.282	4.55	9.31
14	Jim Kaat J. Kaat	625	260	217	.545	625	3.43	2,294	180	31	0	4137.2	4,203	1,579	1,850	366	955	115	0	77	17,336	116	4.99	2.08	2.40	0.80	13.2	5.5	1.25	.282	4.02	9.14
15	Frank Tanana F. Tanana	616	236	236	.500	616	3.67	2,734	143	34	0	4136.1	4,019	1,688	1,893	445	1,227	128	0	110	17,413	114	5.95	2.67	2.23	0.97	15.7	7.0	1.27	.278	4.12	8.74
16	Early Wynn E. Wynn	609	287	230	.555	609	3.53	2,251	289	49	0	4391.1	4,112	1,724	1,963	328	1,710	62	0	32	18,657	50	4.61	3.50	1.32	0.67	12.1	9.2	1.33	.265	4.02	8.43
17	Robin Roberts R. Roberts	608	275	239	.535	608	3.40	2,290	305	45	0	4564.0	4,459	1,724	1,905	495	869	54	0	63	18,702	32	4.52	1.71	2.64	0.98	12.2	4.6	1.17	.264	3.76	8.79
18	Randy Johnson R. Johnson	602	301	165	.646	602	3.28	4,816	100	37	0	4100.2	3,312	1,494	1,681	406	1,485	188	0	37	16,915	109	10.57	3.26	3.24	0.89	28.5	8.8	1.17	.290	3.69	7.27
19	Fergie Jenkins F. Jenkins	594	278	218	.560	594	3.32	3,082	267	49	0	4358.2	4,021	1,608	1,786	463	951	83	0	101	17,815	61	6.36	1.96	3.24	0.96	17.3	5.3	1.14	.269	3.69	8.30
20	Grover Alexander G. Alexander	574	336	183	.647	574	2.48	1,958	417	90	0	4745.2	4,453	1,310	1,634	152	803	59	0		19,084	30	3.71	1.52	2.44	0.29	10.3	4.2	1.11	.267	3.10	8.44
21	Dennis Martinez D. Martinez	562	230	182	.558	562	3.66	1,984	122	30	0	3730.2	3,631	1,517	1,701	349	1,067	113	0	60	15,613	70	4.79	2.57	1.86	0.84	12.7	6.8	1.26	.271	4.10	8.76
22	CC Sabathia	558	251	159	.612	558	3.70	3,085	38	12	0	3570.2	3,384	1,467	1,605	382	1,095	123	0	43	14,944	74	7.78	2.76	2.82	0.96	20.6	7.3	1.25	.293	4.05	8.53
23	Eppa Rixey E. Rixey	553	247	238	.509	553	3.13	1,243	289	37	0	4167.1	4,320	1,451	1,838	84	980	71	0		17,397	84	2.68	2.12	1.27	0.18	7.1	5.6	1.27	.282	3.97	9.33
24	Bartolo Colon B. Colon	552	246	187	.568	552	4.12	2,502	38	13	0	3434.0	3,565	1,571	1,705	436	944	63	0	47	14,541	45	6.56	2.47	2.65	1.14	17.2	6.5	1.31	.295	4.47	9.34
25	Jerry Reuss J. Reuss	543	212	181	.539	543	3.55	1,820	127	39	0	3525.0	3,569	1,391	1,597	230	1,059	55	0	98	14,913	103	4.65	2.70	1.72	0.59	12.2	7.1	1.31	.284	4.08	9.11