Babe Ruth has hit the most career homers by a 25-year-old player, with 54 homers.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Babe Ruth B. Ruth	54	142	458	158	172	36	9	135	150	3	80	14		616	388	99	5				.376	.532	.847	1.379
2	Aaron Judge A. Judge	53	161	565	136	166	27	2	118	143	6	218	11	5	719	356	82	0	5	12	14	.294	.438	.630	1.068
3	Frank Thomas F. Thomas	50	154	546	135	186	37	0	138	135	2	53	4	2	693	373	87	0	10	23	11	.341	.466	.683	1.149
4	Rocky Colavito R. Colavito	50	154	578	98	166	28	1	128	83	2	87	2	3	664	346	79	0	1	12	10	.287	.378	.599	.977
5	Jimmie Foxx J. Foxx	48	149	573	125	204	37	9	163	96	1	93	2		670	403	94	0				.356	.449	.703	1.153
6	Adrian Beltre A. Beltre	47	157	600	104	199	33	0	121	53	2	89	7	2	659	373	80	0	4	9	14	.332	.385	.622	1.007
7	Jim Rice J. Rice	46	163	677	121	213	25	15	139	58	5	126	7	5	746	406	86	1	5	7	15	.315	.370	.600	.970
8	Prince Fielder P. Fielder	44	162	602	108	178	34	2	131	100	12	139	3	3	721	348	80	0	7	21	13	.296	.402	.578	.980
9	Alex Rodriguez A. Rodriguez	44	163	616	131	189	37	2	137	95	13	129	16	4	736	362	83	0	12	5	15	.307	.404	.588	.991
10	Vladimir Guerrero V. Guerrero	44	154	571	101	197	28	11	123	58	8	74	9	10	641	379	83	0	4	23	15	.345	.410	.664	1.074
11	Willie McCovey W. McCovey	44	152	564	103	158	19	5	102	50	11	118	1	1	627	319	68	1	1	5	10	.280	.350	.566	.915
12	Mark Teixeira M. Teixeira	42	164	644	111	201	43	3	145	76	11	118	4	0	734	376	88	0	3	6	18	.312	.392	.584	.976
13	Juan Soto J. Soto	41	157	576	128	166	31	4	109	129	4	119	7	4	713	328	76	0	4	2	10	.288	.419	.569	.989
14	Ronald Acuña Jr. R. Acuña Jr.	41	159	643	149	217	35	4	106	80	9	84	73	14	735	383	80	0	3	3	15	.337	.416	.596	1.012
15	Alex Bregman A. Bregman	41	154	546	122	164	37	2	112	119	9	81	5	1	682	328	80	0	8	2	9	.300	.428	.601	1.029
16	Nolan Arenado N. Arenado	41	163	624	116	184	35	6	125	70	3	108	2	3	705	354	82	0	8	10	18	.295	.365	.567	.932
17	Albert Pujols A. Pujols	41	161	591	129	195	38	2	117	97	9	65	16	2	700	360	81	0	3	27	19	.330	.430	.609	1.039
18	José Ramírez J. Ramírez	40	156	575	110	166	42	4	109	103	7	77	34	6	691	336	86	0	6	15	3	.289	.399	.584	.984
19	Adam Dunn A. Dunn	40	160	543	107	134	35	2	101	114	12	168	4	2	671	293	77	0	2	14	6	.247	.387	.540	.927
20	Frank Robinson F. Robinson	40	153	548	121	183	32	9	128	78	12	66	24	7	648	353	81	0	10	22	14	.334	.421	.644	1.065
21	Ralph Kiner R. Kiner	40	156	555	104	147	19	5	123	112	3	61	1		670	296	64	0			15	.265	.391	.533	.924
22	Chuck Klein C. Klein	40	156	649	158	250	59	8	170	55	4	50	4		721	445	107	13				.385	.436	.686	1.122
23	Darryl Strawberry D. Strawberry	39	154	532	108	151	32	5	104	97	7	122	36	12	640	310	76	0	4	13	4	.284	.398	.583	.981
24	Harmon Killebrew H. Killebrew	39	158	554	85	131	20	4	103	114	6	137	1	2	678	276	63	0	4	7	15	.236	.370	.498	.868
25	Hank Aaron H. Aaron	39	154	629	116	223	46	7	123	51	4	54	8	0	693	400	92	0	9	17	19	.355	.401	.636	1.037