Between the 1996 and 2004 seasons, Sammy Sosa launched the most homers, with 443 homers.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Sammy Sosa S. Sosa	443	1,336	5,140	964	1,482	230	16	1,107	658	29	1,391	74	41	5,879	3,073	689	0	52	121	122	.288	.369	.598	.967	1078	341.4	.401	141	317.3
2	Barry Bonds B. Bonds	411	1,291	4,078	1,071	1,294	257	29	979	1,371	60	633	166	38	5,546	2,842	697	1	36	408	72	.317	.491	.697	1.188	1379	684.8	.477	196	686.9
3	Alex Rodriguez A. Rodriguez	376	1,365	5,394	1,102	1,663	303	22	1,075	630	82	1,064	198	48	6,177	3,138	701	14	57	43	128	.308	.385	.582	.967	1174	400.6	.409	146	366.7
4	Jim Thome J. Thome	368	1,330	4,584	932	1,307	250	17	995	1,025	36	1,420	6	11	5,686	2,695	635	0	41	111	72	.285	.416	.588	1.004	1142	429.1	.422	154	395
5	Rafael Palmeiro R. Palmeiro	357	1,421	5,246	858	1,467	276	11	1,069	816	45	764	35	16	6,167	2,836	644	0	60	106	104	.280	.377	.541	.918	1061	288.1	.387	131	247.3
6	Manny Ramirez M. Ramirez	340	1,285	4,745	926	1,524	332	13	1,098	755	62	1,038	23	22	5,613	2,902	685	0	51	119	137	.321	.417	.612	1.029	1167	463.8	.430	159	425.8
7	Jeff Bagwell J. Bagwell	333	1,427	5,174	1,072	1,518	326	16	1,041	1,018	89	1,084	145	55	6,334	2,875	675	0	53	104	149	.293	.414	.556	.970	1223	428.3	.412	150	409.9
8	Carlos Delgado C. Delgado	324	1,341	4,786	865	1,370	338	11	1,023	795	119	1,170	8	6	5,758	2,702	673	0	58	124	87	.286	.397	.565	.961	1070	348.4	.404	142	313
9	Ken Griffey Jr. K. Griffey Jr.	312	1,080	3,939	750	1,117	199	17	859	558	53	793	86	23	4,597	2,286	528	3	44	101	73	.284	.376	.580	.956	832	251.5	.398	137	225.2
10	Mark McGwire M. McGwire	306	780	2,528	546	705	102	1	667	644	35	763	5	0	3,232	1,727	409	0	25	96	55	.279	.428	.683	1.111	736	327	.453	174	315.9
11	Gary Sheffield G. Sheffield	298	1,306	4,606	908	1,401	247	12	923	904	75	584	109	50	5,642	2,566	557	0	57	81	113	.304	.422	.557	.979	1111	403.2	.417	156	408.6
12	Chipper Jones C. Jones	287	1,394	5,089	946	1,564	302	24	953	863	14	777	110	36	6,028	2,775	613	2	60	101	139	.307	.405	.545	.950	1119	362.9	.403	144	344.5
13	Mike Piazza M. Piazza	286	1,201	4,350	703	1,360	223	4	857	544	18	676	12	13	4,943	2,449	513	0	31	112	168	.313	.389	.563	.952	903	282.5	.400	146	293.5
14	Jason Giambi J. Giambi	275	1,290	4,581	824	1,368	289	8	919	843	89	885	11	9	5,574	2,498	572	1	60	63	111	.299	.413	.545	.958	1063	364.1	.409	149	352.2
15	Vladimir Guerrero V. Guerrero	273	1,160	4,375	765	1,421	265	36	828	433	58	558	138	74	4,900	2,577	574	0	34	144	141	.325	.390	.589	.979	924	311.7	.407	144	282.7
16	Juan Gonzalez J. Gonzalez	267	1,005	3,966	670	1,219	249	14	889	288	30	746	12	8	4,340	2,297	530	0	56	46	107	.307	.354	.579	.933	757	211	.390	131	176.2
17	Shawn Green S. Green	266	1,376	5,107	854	1,448	315	23	830	579	57	999	137	41	5,783	2,607	604	2	38	62	121	.284	.360	.510	.871	917	192.2	.372	125	185.1
18	Jim Edmonds J. Edmonds	264	1,192	4,182	815	1,240	278	14	761	651	36	1,054	49	33	4,916	2,338	556	4	43	61	72	.297	.392	.559	.951	909	294.5	.403	143	273.1
19	Jeromy Burnitz J. Burnitz	259	1,283	4,379	719	1,117	240	21	792	599	68	1,082	64	46	5,085	2,176	520	5	34	64	75	.255	.351	.497	.848	764	127.1	.362	114	95.3
20	Vinny Castilla V. Castilla	259	1,308	5,038	687	1,399	248	17	873	320	43	777	23	27	5,451	2,458	524	1	49	49	173	.278	.323	.488	.811	739	56.8	.345	93	-54.7
21	Frank Thomas F. Thomas	254	1,136	4,087	743	1,220	259	3	844	789	53	691	16	10	4,987	2,247	516	0	58	79	105	.299	.413	.550	.963	952	325.8	.410	146	303.1
22	Todd Helton T. Helton	251	1,135	4,051	832	1,372	328	22	836	667	31	542	30	23	4,798	2,497	601	2	47	109	97	.339	.432	.616	1.048	1031	430.6	.438	147	291.2
23	Andruw Jones A. Jones	250	1,291	4,685	760	1,254	250	29	766	501	47	1,017	124	49	5,276	2,312	529	6	37	39	112	.268	.342	.493	.835	771	110.8	.357	113	92
24	Steve Finley S. Finley	238	1,370	5,107	841	1,401	273	54	779	502	32	779	120	50	5,709	2,496	565	22	46	42	90	.274	.340	.489	.829	821	104.2	.354	111	81.7
25	Jeff Kent J. Kent	236	1,303	4,916	804	1,451	347	32	944	483	64	918	76	38	5,538	2,570	615	2	73	32	134	.295	.361	.523	.884	900	206.6	.376	128	200.3