Albert Pujols has hit the most career homers when the count has been 1 and 1, with 100 home runs.

Interpreted as:

most homers by a player when the count was 1 and 1

	NAME	HR	G	AB	H	2B	3B	RBI	BB	HBP	SO	PA	TB	XBH	SH	SF	IBB	AVG	OBP	SLG	OPS
1	Albert Pujols A. Pujols	100	1,084	1,260	441	96	3	293	0	12	0	1,284	843	199	0	12	0	.350	.353	.669	1.022
2	David Ortiz D. Ortiz	76	696	789	273	74	3	204	0	4	0	803	581	153	0	10	0	.346	.345	.736	1.081
3	Barry Bonds B. Bonds	74	715	807	293	46	12	170	0	7	0	824	585	132	0	10	0	.363	.364	.725	1.089
4	Alex Rodriguez A. Rodriguez	72	852	975	353	65	4	215	0	14	0	999	642	141	0	10	0	.362	.367	.658	1.026
5	Jim Thome J. Thome	72	596	657	247	47	4	181	0	3	0	666	518	123	0	6	0	.376	.375	.788	1.164
6	Gary Sheffield G. Sheffield	68	885	1,017	332	53	3	202	0	13	0	1,049	595	124	1	18	0	.326	.329	.585	.914
7	Mark McGwire M. McGwire	67	426	469	181	27	0	130	0	6	0	480	409	94	0	5	0	.386	.390	.872	1.262
8	Adrian Beltre A. Beltre	65	960	1,098	361	81	2	219	0	7	0	1,123	641	148	3	15	0	.329	.329	.584	.912
9	Sammy Sosa S. Sosa	65	652	719	252	37	4	157	0	10	0	741	492	106	6	6	0	.350	.356	.684	1.041
10	Ken Griffey Jr. K. Griffey Jr.	63	752	837	289	56	4	189	0	13	0	861	542	123	1	10	0	.345	.351	.648	.999
11	Mike Trout M. Trout	61	494	549	216	30	4	127	0	11	0	566	437	95	0	6	0	.393	.401	.796	1.197
12	Miguel Cabrera M. Cabrera	61	853	974	360	65	3	218	0	6	0	993	614	129	1	12	0	.370	.369	.630	.999
13	Carlos Delgado C. Delgado	61	554	611	210	48	0	163	0	15	0	633	441	109	0	7	0	.344	.355	.722	1.077
14	Mike Piazza M. Piazza	60	639	737	262	37	1	163	0	2	0	745	481	98	0	6	0	.355	.354	.653	1.007
15	Manny Ramirez M. Ramirez	57	607	676	278	70	0	201	0	9	0	694	519	127	1	8	0	.411	.414	.768	1.182
16	Frank Thomas F. Thomas	56	667	733	280	54	1	195	0	17	0	762	504	111	0	12	0	.382	.390	.688	1.077
17	Edwin Encarnacion E. Encarnacion	55	583	640	200	42	0	161	0	5	0	655	407	97	0	8	0	.313	.314	.636	.950
18	Mark Teixeira M. Teixeira	55	597	673	234	41	1	163	0	12	0	692	442	97	0	7	0	.348	.355	.657	1.012
19	Rafael Palmeiro R. Palmeiro	55	876	1,005	327	52	4	184	0	11	0	1,025	552	111	2	7	0	.325	.330	.549	.880
20	Nelson Cruz N. Cruz	53	542	611	223	45	3	133	1	9	0	627	433	101	0	5	1	.365	.372	.709	1.081
21	Jason Giambi J. Giambi	51	595	638	237	47	1	153	0	28	0	672	439	99	1	5	0	.371	.395	.688	1.083
22	Fred McGriff F. McGriff	51	614	674	241	39	1	131	0	3	0	679	435	91	0	2	0	.358	.359	.645	1.005
23	Adam Dunn A. Dunn	50	468	504	180	37	2	128	0	11	0	519	371	89	0	4	0	.357	.368	.736	1.104
24	Carlos Lee C. Lee	50	659	760	248	48	2	172	0	2	0	775	450	100	0	12	0	.326	.323	.592	.915
25	Aramis Ramirez A. Ramirez	50	712	803	279	64	4	185	0	12	0	827	501	118	0	12	0	.347	.352	.624	.976