Since 2000, 6 pitchers are tied for giving up the most home runs in a game, with 6 HR. The first three are Miles Mikolas on July 4, Matt Swarmer on June 11, 2022 and Michael Blazek on July 27, 2017.
Interpreted as:
most hrs in a regular-season game by one pitcher since 2000| NAME | HR | DATE | TM | OPP | DEC | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Mikolas | 6 | 7/4/2025 |  STL | @ |  CHC | L | 1 | 12.00 | 4 | 0 | 0 | 0 | 6.0 | 10 | 8 | 8 | 0 | 0 | 0 | 0 | 28 | 0 |
| 2 |  | M. Swarmer | 6 | 6/11/2022 | CHC | @ |  NYY | L | 1 | 10.80 | 4 | 0 | 0 | 0 | 5.0 | 7 | 6 | 6 | 0 | 0 | 0 | 0 | 22 | 0 |
| 3 | | M. Blazek | 6 | 7/27/2017 |  MIL | @ |  WSH | L | 1 | 30.86 | 4 | 0 | 0 | 0 | 2.1 | 7 | 8 | 8 | 1 | 0 | 0 | 0 | 15 | 0 |
| 4 | | J. Shields | 6 | 8/7/2010 |  TBR | @ |  TOR | L | 1 | 18.00 | 2 | 0 | 0 | 0 | 4.0 | 9 | 8 | 8 | 4 | 0 | 0 | 0 | 25 | 1 |
| 5 | | R.A. Dickey | 6 | 4/6/2006 |  TEX | vs |  DET | L | 1 | 18.90 | 1 | 0 | 0 | 0 | 3.1 | 8 | 7 | 7 | 1 | 0 | 0 | 0 | 18 | 0 |
| 6 | | T. Wakefield | 6 | 8/8/2004 |  BOS | @ | DET | W | 1 | 12.60 | 2 | 0 | 0 | 0 | 5.0 | 8 | 7 | 7 | 0 | 0 | 0 | 0 | 23 | 0 |
| 7 | | S. Baz | 5 | 8/19/2025 | TBR | vs | NYY | L | 1 | 18.00 | 3 | 0 | 0 | 0 | 3.0 | 7 | 6 | 6 | 2 | 0 | 0 | 0 | 18 | 0 |
| 8 | | A. Molina | 5 | 8/5/2025 |  COL | vs |  TOR | L | 1 | 12.60 | 2 | 0 | 0 | 0 | 5.0 | 9 | 7 | 7 | 1 | 0 | 0 | 0 | 24 | 0 |
| 9 | | M. Spence | 5 | 7/9/2025 |  ATH | vs |  ATL | L | 1 | 12.00 | 3 | 0 | 0 | 0 | 6.0 | 9 | 8 | 8 | 1 | 0 | 0 | 0 | 28 | 0 |
| 10 | | K. Gibson | 5 | 4/29/2025 |  BAL | vs | NYY | L | 1 | 22.09 | 2 | 0 | 0 | 0 | 3.2 | 11 | 9 | 9 | 2 | 0 | 0 | 0 | 24 | 0 |
| 11 | | B. Francis | 5 | 4/29/2025 | TOR | vs | BOS | L | 1 | 21.00 | 1 | 0 | 0 | 0 | 3.0 | 8 | 7 | 7 | 0 | 0 | 0 | 0 | 17 | 0 |
| 12 |  | N. Cortes | 5 | 3/29/2025 |  MIL | @ | NYY | L | 1 | 36.00 | 2 | 0 | 0 | 0 | 2.0 | 6 | 8 | 8 | 5 | 0 | 0 | 0 | 17 | 0 |
| 13 | | C. Spiers | 5 | 8/20/2024 |  CIN | @ | TOR | L | 1 | 18.69 | 3 | 0 | 0 | 0 | 4.1 | 13 | 9 | 10 | 2 | 1 | 0 | 0 | 28 | 0 |
| 14 | | K. Crawford | 5 | 7/21/2024 | BOS | @ |  LAD | L | 1 | 10.80 | 2 | 0 | 0 | 0 | 5.0 | 7 | 6 | 6 | 0 | 0 | 0 | 0 | 22 | 0 |
| 15 | | M. Pérez | 5 | 5/15/2024 |  PIT | @ | MIL | L | 1 | 16.20 | 4 | 0 | 0 | 0 | 5.0 | 11 | 9 | 9 | 1 | 0 | 0 | 0 | 26 | 0 |
| 16 |  | H. Greene | 5 | 8/20/2023 | CIN | vs | TOR | L | 1 | 24.00 | 4 | 0 | 0 | 0 | 3.0 | 10 | 8 | 9 | 3 | 0 | 0 | 0 | 24 | 1 |
| 17 | | T. Gonsolin | 5 | 8/18/2023 | LAD | vs |  MIA | L | 1 | 27.00 | 2 | 0 | 0 | 0 | 3.1 | 8 | 10 | 10 | 4 | 0 | 0 | 0 | 22 | 0 |
| 18 |  | J. Ryan | 5 | 6/27/2023 |  MIN | @ | ATL | L | 1 | 18.00 | 5 | 0 | 0 | 0 | 3.0 | 9 | 6 | 6 | 0 | 0 | 0 | 0 | 18 | 0 |
| 19 | | J. Fleming | 5 | 5/28/2023 | TBR | vs | LAD | 1 | 12.00 | 3 | 0 | 0 | 0 | 6.0 | 12 | 8 | 10 | 2 | 0 | 0 | 1 | 32 | 0 | |
| 20 | | J. Suarez | 5 | 4/24/2023 |  LAA | vs | OAK | 1 | 12.60 | 5 | 0 | 0 | 0 | 5.0 | 8 | 7 | 7 | 2 | 0 | 0 | 0 | 23 | 0 | |
| 21 | | M. Kopech | 5 | 4/3/2023 |  CWS | vs |  SFG | L | 1 | 13.50 | 5 | 0 | 0 | 0 | 4.2 | 8 | 7 | 7 | 3 | 0 | 0 | 0 | 25 | 0 |
| 22 | | T. Romero | 5 | 10/1/2022 | WSH | vs |  PHI | L | 1 | 14.73 | 2 | 0 | 0 | 0 | 3.2 | 8 | 6 | 8 | 4 | 0 | 0 | 0 | 23 | 0 |
| 23 | | H. Gaddis | 5 | 9/15/2022 |  CLE | vs | CWS | L | 1 | 15.75 | 3 | 0 | 0 | 0 | 4.0 | 8 | 7 | 7 | 1 | 0 | 0 | 0 | 21 | 0 |
| 24 | | J. Ryan | 5 | 7/29/2022 | MIN | @ |  SDP | L | 1 | 19.29 | 7 | 0 | 0 | 0 | 4.2 | 8 | 10 | 10 | 2 | 0 | 0 | 0 | 24 | 0 |
| 25 |  | G. Cole | 5 | 6/9/2022 | NYY | @ | MIN | 1 | 27.00 | 3 | 0 | 0 | 0 | 2.1 | 8 | 7 | 7 | 2 | 0 | 0 | 0 | 17 | 0 | |
Some of the information used here was obtained free of charge from Retrosheet.
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