The New York Mets have pitched the most innings by a team in a loss, with 25 innings against the Cardinals on September 11, 1974.

Interpreted as:

most ip in a regular-season loss

	TEAM	IP	L	DATE	TM		OPP	RESULT	W	L%	ERA	SO	SHO	SV	H	ER	R	HR	BB	HBP	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Mets	25.0	1	9/11/1974	NYM	vs	STL	L 3-4	0	1.000	1.08	12	0	0	18	3	4	1	8	2	3	99	2	4.32	2.88	1.50	0.36	12.1	8.1	1.04	.224	1.44	6.48
2	Brewers	24.1	1	5/8/1984	MIL	@	CWS	L 6-7	0	1.000	1.11	17	0	0	23	3	7	1	7	0	2	104	0	6.29	2.59	2.43	0.37	16.3	6.7	1.23	.278	2.59	8.51
3	Americans	24.0	1	9/1/1906	BSA	vs	PHA	L 1-4	0	1.000	0.00	14	0	0	16	0	4	0	2	1		87	0	5.25	0.75	7.00	0.00	16.1	2.3	0.75	.229	1.50	6.00
4	Mets	23.1	1	4/15/1968	NYM	@	HOU	L 0-1	0	1.000	0.39	15	0	0	11	1	1	0	7	0	4	87	2	5.79	2.70	2.14	0.00	17.2	8.0	0.77	.169	0.39	4.24
5	Mets	23.0	1	5/31/1964	NYM	vs	SFG	L 6-8	0	1.000	3.13	14	0	0	17	8	8	0	9	1	1	93	0	5.48	3.52	1.56	0.00	15.1	9.7	1.13	.246	3.13	6.65
6	Padres	22.0	1	4/17/2008	SDP	vs	COL	L 1-2	0	1.000	0.41	20	0	0	14	1	2	0	8	0	1	84	0	8.18	3.27	2.50	0.00	23.8	9.5	1.00	.250	0.82	5.73
7	Expos	22.0	1	8/23/1989	MON	vs	LAD	L 0-1	0	1.000	0.41	17	0	0	20	1	1	1	0	0	0	81	0	6.95	0.00		0.41	21.0	0.0	0.91	.302	0.41	8.18
8	Twins	22.0	1	5/12/1972	MIN	vs	MIL	L 3-4	0	1.000	1.64	13	0	0	13	4	4	0	8	0	2	86	0	5.32	3.27	1.63	0.00	15.1	9.3	0.95	.200	1.64	5.32
9	Tigers	22.0	1	6/24/1962	DET	vs	NYY	L 7-9	0	1.000	3.68	12	0	0	20	9	9	2	9	0	1	96	2	4.91	3.68	1.33	0.82	12.5	9.4	1.32	.247	3.68	8.18
10	Braves	22.0	1	5/17/1927	BSN	vs	CHC	L 3-4	0	1.000	0.00	5	0	0	20	0	4	0	9	0		89	0	2.05	3.68	0.56	0.00	5.6	10.1	1.32	.267	1.64	8.18
11	Dodgers	21.2	1	6/3/1989	LAD	@	HOU	L 4-5	0	1.000	2.08	17	0	0	18	5	5	1	8	0	2	88	0	7.06	3.32	2.13	0.42	19.3	9.1	1.20	.274	2.08	7.48
12	Pirates	21.2	1	8/22/1917	PIT	@	BKN	L 5-6	0	1.000	0.00	1	0	0	28	0	6	0	4	0		89	0	0.42	1.66	0.25	0.00	1.1	4.5	1.48	.333	2.49	11.63
13	White Sox	21.1	1	6/12/1967	CWS	@	WSH	L 5-6	0	1.000	2.53	9	0	0	13	6	6	3	7	0	2	78	2	3.80	2.95	1.29	1.27	11.5	9.0	0.94	.169	2.53	5.48
14	Indians	21.0	1	8/31/1993	CLE	@	MIN	L 4-5	0	1.000	1.71	17	0	0	17	4	5	1	7	0	2	85	1	7.29	3.00	2.43	0.43	20.0	8.2	1.14	.267	2.14	7.29
15	Cubs	21.0	1	8/17/1982	CHC	vs	LAD	L 1-2	0	1.000	0.86	13	0	0	17	2	2	0	8	0	1	86	2	5.57	3.43	1.63	0.00	15.1	9.3	1.19	.262	0.86	7.29
16	Expos	21.0	1	5/21/1977	MON	vs	SDP	L 8-11	0	1.000	3.43	12	0	0	13	8	11	3	13	0	4	87	0	5.14	5.57	0.92	1.29	13.8	14.9	1.24	.169	4.71	5.57
17	Padres	21.0	1	9/24/1971	SDP	vs	HOU	L 1-2	0	1.000	0.86	16	0	0	11	2	2	1	5	0	0	78	0	6.86	2.14	3.20	0.43	20.5	6.4	0.76	.179	0.86	4.71
18	Senators	21.0	1	6/4/1971	WSH	vs	OAK	L 3-5	0	1.000	2.14	11	0	0	16	5	5	0	9	0	1	85	2	4.71	3.86	1.22	0.00	12.9	10.6	1.19	.246	2.14	6.86
19	Reds	21.0	1	9/1/1967	CIN	vs	SFG	L 0-1	0	1.000	0.43	18	0	0	15	1	1	0	4	1	1	82	1	7.71	1.71	4.50	0.00	22.0	4.9	0.90	.254	0.43	6.43
20	White Sox	21.0	1	5/24/1929	CWS	vs	DET	L 5-6	0	1.000	0.00	4	0	0	24	0	6	0	2	0		85	0	1.71	0.86	2.00	0.00	4.7	2.4	1.24	.304	2.57	10.29
21	Braves	21.0	1	8/1/1918	BSN	vs	PIT	L 0-2	0	1.000	0.00	8	0	0	12	0	2	0	5	0		77	0	3.43	2.14	1.60	0.00	10.4	6.5	0.81	.188	0.86	5.14
22	Pirates	21.0	1	7/17/1914	PTN	vs	NYG	L 1-3	0	1.000	0.00	6	0	0	12	0	3	1	0	0		75	0	2.57	0.00		0.43	8.0	0.0	0.57	.162	1.29	5.14
23	Indians	20.2	1	5/26/1973	CLE	@	CWS	L 3-6	0	1.000	2.61	13	0	0	17	6	6	2	8	0	2	84	3	5.66	3.48	1.63	0.87	15.5	9.5	1.21	.246	2.61	7.40
24	Mets	20.0	1	6/8/2013	NYM	vs	MIA	L 1-2	0	1.000	0.90	16	0	0	15	2	2	0	2	0	0	72	0	7.20	0.90	8.00	0.00	22.2	2.8	0.85	.278	0.90	6.75
25	Cardinals	20.0	1	4/17/2010	STL	vs	NYM	L 1-2	0	1.000	0.90	16	0	0	9	2	2	0	8	1	2	75	0	7.20	3.60	2.00	0.00	21.3	10.7	0.85	.180	0.90	4.05