The Cleveland Spiders have lost the most games by a team in a season, with 134 losses in 1899.

	TEAM	L	SEASON	W	L%	G	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Spiders	134	1899	20	.870	154	.130	5,279	529	1,333	142	50	12	454	289	65	280	127		5,690	1,611	204	57				.253	.299	.305	.605
2	White Sox	121	2024	41	.747	162	.253	5,383	507	1,187	226	9	133	485	395	43	1,403	90	33	5,866	1,830	368	18	27	8	116	.221	.278	.340	.618
3	Mets	120	1962	40	.750	161	.250	5,492	617	1,318	166	40	139	573	616	32	991	59	48	6,242	1,981	345	58	44	29	122	.240	.318	.361	.679
4	Rockies	119	2025	43	.735	162	.265	5,408	597	1,281	253	37	160	581	395	48	1,531	87	39	5,907	2,088	450	21	35	5	118	.237	.293	.386	.679
5	Tigers	119	2003	43	.735	162	.265	5,466	591	1,312	201	39	153	553	443	47	1,099	98	63	6,070	2,050	393	65	49	24	114	.240	.300	.375	.675
6	Athletics	117	1916	36	.765	154	.235	5,010	447	1,212	169	65	19	380	406	30	631	151		5,603	1,568	253	157				.242	.303	.313	.616
7	Orioles	115	2018	47	.710	162	.290	5,507	622	1,317	242	15	188	593	422	57	1,412	81	22	6,034	2,153	445	13	35	19	132	.239	.298	.391	.689
8	Braves	115	1935	38	.752	153	.248	5,309	575	1,396	233	33	75	544	353	19	436	20		5,761	1,920	341	80			139	.263	.311	.362	.673
9	Tigers	114	2019	47	.708	161	.292	5,549	582	1,333	292	41	149	556	391	48	1,595	57	20	6,039	2,154	482	9	42	14	108	.240	.294	.388	.682
10	Senators	113	1904	38	.748	157	.252	5,149	437	1,170	171	57	10	348	283	59	756	150		5,606	1,485	238	115				.227	.275	.288	.564
11	Alleghenys	113	1890	23	.831	138	.169	4,739	597	1,088	160	43	20	426	408	66	460	208		5,213	1,394	223					.230	.300	.294	.594
12	Athletics	112	2023	50	.691	162	.309	5,311	585	1,187	225	21	171	563	498	85	1,496	149	31	5,958	1,967	417	28	36	12	125	.223	.298	.370	.669
13	Mets	112	1965	50	.691	164	.309	5,441	495	1,202	203	27	107	460	392	39	1,129	28	42	5,976	1,780	337	76	28	40	121	.221	.277	.327	.604
14	Pirates	112	1952	42	.727	155	.273	5,193	515	1,201	181	30	92	478	486	26	724	43	41	5,775	1,718	303	70			104	.231	.300	.331	.631
15	Astros	111	2013	51	.685	162	.315	5,457	610	1,307	266	16	148	566	426	52	1,535	110	61	6,019	2,049	430	46	38	17	110	.240	.299	.375	.674
16	Diamondbacks	111	2004	51	.685	162	.315	5,544	615	1,401	295	38	135	582	441	35	1,022	53	32	6,113	2,177	468	56	37	38	137	.253	.310	.393	.703
17	Mets	111	1963	51	.685	162	.315	5,336	501	1,168	156	35	96	459	457	47	1,078	41	52	5,921	1,682	287	46	35	41	106	.219	.285	.315	.600
18	Phillies	111	1941	43	.721	155	.279	5,233	501	1,277	188	38	64	467	451	22	595	65		5,796	1,733	290	90			142	.244	.307	.331	.638
19	Browns	111	1939	43	.721	156	.279	5,422	733	1,453	242	50	91	696	558	20	606	48	38	6,132	2,068	383	132			121	.268	.339	.381	.720
20	Red Sox	111	1932	43	.721	154	.279	5,294	566	1,330	253	57	53	529	470	12	537	46	46	5,856	1,856	363	80				.251	.314	.351	.664
21	Browns	111	1898	39	.740	154	.260	5,214	571	1,290	149	55	13	470	383	84	405	104		5,798	1,588	217	117				.247	.309	.305	.614
22	Colonels	111	1889	27	.804	140	.196	4,955	632	1,249	170	75	22	503	320	41	521	203		5,316	1,635	267					.252	.303	.330	.633
23	Orioles	110	2021	52	.679	162	.321	5,420	659	1,296	266	15	195	632	451	65	1,454	54	23	5,981	2,177	476	14	31	12	105	.239	.304	.402	.705
24	Diamondbacks	110	2021	52	.679	162	.321	5,489	679	1,297	308	31	144	644	537	54	1,465	43	16	6,140	2,099	483	32	28	24	99	.236	.309	.382	.692
25	Expos	110	1969	52	.679	162	.321	5,419	582	1,300	202	33	125	542	529	38	962	52	52	6,073	1,943	360	57	30	51	132	.240	.310	.359	.669