Babe Ruth has the most career games when collecting 3+ RBI, with 255 games.

Interpreted as:

most MLB regular-season games by a player getting at least 3 rbis

	NAME	G	RBI	AB	R	H	2B	3B	HR	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Babe Ruth B. Ruth	255	896	1,000	451	565	82	22	276	211	4	89	14		1,236	1,519	380	21				.565	.642	1.519	2.161
2	Hank Aaron H. Aaron	232	799	980	363	509	68	9	252	91	2	67	8	2	1,085	1,351	329	0	12	20	19	.519	.555	1.379	1.933
3	Albert Pujols A. Pujols	222	777	931	367	496	99	0	240	95	11	73	5	3	1,053	1,315	339	0	16	22	24	.533	.572	1.412	1.984
4	Jimmie Foxx J. Foxx	219	787	879	366	473	70	22	227	150	1	79	8		1,046	1,268	319	16			6	.538	.606	1.443	2.048
5	Lou Gehrig L. Gehrig	218	821	911	411	521	92	34	216	160	6	44	12		1,093	1,329	342	16				.572	.638	1.459	2.097
6	Alex Rodriguez A. Rodriguez	211	761	898	362	480	72	2	233	103	7	125	25	3	1,028	1,255	307	1	19	9	14	.535	.574	1.398	1.972
7	Mel Ott M. Ott	205	706	845	351	445	68	12	204	128	4	45	12		984	1,149	284	7			0	.527	.591	1.360	1.950
8	Manny Ramirez M. Ramirez	203	724	815	327	450	84	2	220	90	7	120	1	2	930	1,198	306	0	18	12	18	.552	.588	1.470	2.058
9	Ted Williams T. Williams	202	718	798	343	438	66	14	205	174	2	41	1	0	978	1,147	285	1	3	12	14	.549	.628	1.437	2.066
10	Barry Bonds B. Bonds	201	699	757	353	445	66	12	232	155	7	73	39	8	932	1,231	310	0	13	36	8	.588	.651	1.626	2.277
11	Miguel Cabrera M. Cabrera	193	668	810	286	466	92	2	183	77	5	105	1	3	906	1,111	277	1	13	19	16	.575	.606	1.372	1.977
12	David Ortiz D. Ortiz	192	661	777	271	397	87	6	191	86	3	97	0	0	884	1,069	284	0	18	17	14	.511	.550	1.376	1.926
13	Al Simmons A. Simmons	192	673	892	285	483	86	29	131	45	5	35	10		962	1,020	246	20			0	.541	.566	1.143	1.709
14	Ken Griffey Jr. K. Griffey Jr.	184	642	769	299	383	58	6	212	74	7	99	14	4	867	1,089	276	1	16	18	6	.498	.536	1.416	1.952
15	Sammy Sosa S. Sosa	182	660	781	304	403	46	9	226	56	3	126	11	6	851	1,145	281	1	10	11	13	.516	.544	1.466	2.010
16	Eddie Murray E. Murray	179	624	748	244	384	62	2	162	78	1	60	9	2	842	936	226	0	15	10	13	.513	.550	1.251	1.801
17	Stan Musial S. Musial	179	606	740	285	415	50	25	167	99	1	33	6	2	852	1,016	242	1	11	11	15	.561	.605	1.373	1.978
18	Willie Mays W. Mays	175	590	722	313	392	40	16	205	77	1	63	26	6	811	1,079	261	0	11	12	14	.543	.580	1.494	2.074
19	Frank Thomas F. Thomas	174	597	708	263	362	63	3	173	94	2	84	1	0	827	950	239	0	23	12	12	.511	.554	1.342	1.896
20	Frank Robinson F. Robinson	173	599	705	301	381	48	7	198	83	9	68	15	4	813	1,037	253	1	15	16	11	.540	.583	1.471	2.053
21	Rafael Palmeiro R. Palmeiro	171	581	716	261	387	62	5	173	82	4	67	4	4	818	978	240	0	16	6	12	.541	.578	1.366	1.944
22	Jim Thome J. Thome	170	577	661	263	332	58	3	183	120	2	142	1	1	793	945	244	0	10	18	9	.502	.573	1.430	2.002
23	Ernie Banks E. Banks	169	590	678	248	360	46	12	183	58	3	53	3	1	758	979	241	1	18	14	10	.531	.556	1.444	2.000
24	Dave Winfield D. Winfield	168	582	721	237	368	53	9	157	59	3	79	7	5	798	910	219	2	13	19	13	.510	.540	1.262	1.802
25	Mike Schmidt M. Schmidt	166	568	645	273	340	46	7	198	93	8	77	11	10	757	994	251	0	11	18	14	.527	.583	1.541	2.124