20 pitchers are tied for the most career perfect games, with 1. The first three are Domingo Germán, Dallas Braden and Philip Humber.

Interpreted as:

most regular-season perfect games by a pitcher

	NAME	PG	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Domingo Germán D. Germán	1	119	31	29	.517	91	4.54	561	1	1	0	543.0	479	274	293	98	174	24	11	1	2,283	22	9.30	2.88	3.22	1.62	24.6	7.6	1.20	.267	4.86	7.94
2	Dallas Braden D. Braden	1	94	26	36	.419	79	4.16	305	5	2	0	491.1	510	227	248	45	141	11	8	5	2,076	9	5.59	2.58	2.16	0.82	14.7	6.8	1.32	.295	4.54	9.34
3	Philip Humber P. Humber	1	97	16	23	.410	51	5.31	272	1	1	0	371.0	398	219	223	53	129	13	17	8	1,630	26	6.60	3.13	2.11	1.29	16.7	7.9	1.42	.297	5.41	9.65
4	Matt Cain M. Cain	1	342	104	118	.468	331	3.68	1,694	15	6	0	2085.2	1,849	853	910	211	712	62	4	42	8,699	70	7.31	3.07	2.38	0.91	19.5	8.2	1.23	.272	3.93	7.98
5	Felix Hernandez F. Hernandez	1	419	169	136	.554	418	3.42	2,524	25	11	0	2729.2	2,487	1,037	1,157	264	805	105	0	16	11,284	156	8.32	2.65	3.14	0.87	22.4	7.1	1.21	.293	3.81	8.20
6	Mark Buehrle M. Buehrle	1	518	214	160	.572	493	3.81	1,870	33	10	0	3283.1	3,472	1,391	1,542	361	734	79	6	49	13,705	27	5.13	2.01	2.55	0.99	13.6	5.4	1.28	.292	4.23	9.52
7	Roy Halladay R. Halladay	1	416	203	105	.659	390	3.38	2,117	67	20	1	2749.1	2,646	1,034	1,135	236	592	81	6	28	11,287	56	6.93	1.94	3.58	0.77	18.8	5.2	1.18	.292	3.72	8.66
8	Kenny Rogers K. Rogers	1	762	219	156	.584	474	4.27	1,968	36	9	28	3302.2	3,457	1,568	1,739	339	1,175	127	133	53	14,280	79	5.36	3.20	1.67	0.92	13.8	8.2	1.40	.292	4.74	9.42
9	Randy Johnson R. Johnson	1	618	303	166	.646	603	3.29	4,875	100	37	2	4135.1	3,346	1,513	1,703	411	1,497	190	7	37	17,067	109	10.61	3.26	3.26	0.89	28.6	8.8	1.17	.291	3.71	7.28
10	David Wells D. Wells	1	660	239	157	.604	489	4.13	2,201	54	12	13	3439.0	3,635	1,578	1,702	407	719	83	65	65	14,413	101	5.76	1.88	3.06	1.07	15.3	5.0	1.27	.293	4.45	9.51
11	David Cone D. Cone	1	450	194	126	.606	419	3.47	2,668	56	22	1	2898.2	2,504	1,116	1,222	258	1,137	106	9	42	12,184	149	8.28	3.53	2.35	0.80	21.9	9.3	1.26	.280	3.79	7.77
12	Tom Browning T. Browning	1	302	123	90	.577	300	3.94	1,000	31	12	0	1921.0	1,931	841	913	236	511	32	1	61	8,066	25	4.69	2.39	1.96	1.11	12.4	6.3	1.27	.270	4.28	9.05
13	Mike Witt M. Witt	1	341	117	116	.502	299	3.83	1,373	72	11	6	2108.1	2,066	898	1,012	183	713	55	22	40	8,927	73	5.86	3.04	1.93	0.78	15.4	8.0	1.32	.285	4.32	8.82
14	Len Barker L. Barker	1	248	74	76	.493	194	4.34	975	35	7	5	1323.2	1,289	639	695	96	513	21	26	20	5,674	65	6.63	3.49	1.90	0.65	17.2	9.0	1.36	.293	4.73	8.76
15	Dennis Martinez D. Martinez	1	692	245	193	.559	562	3.70	2,149	122	30	8	3999.2	3,897	1,643	1,835	372	1,165	122	51	70	16,754	84	4.84	2.62	1.84	0.84	12.8	7.0	1.27	.272	4.13	8.77
16	Catfish Hunter C. Hunter	1	500	224	166	.574	476	3.26	2,011	181	42	1	3449.1	2,958	1,248	1,380	374	954	49	6	57	14,032	49	5.25	2.49	2.11	0.98	14.3	6.8	1.13	.243	3.60	7.72
17	Jim Bunning J. Bunning	1	591	224	184	.549	519	3.27	2,855	151	40	16	3760.0	3,433	1,365	1,527	372	1,000	160	39	98	15,615	47	6.83	2.39	2.86	0.89	18.3	6.4	1.18	.273	3.66	8.22
18	Sandy Koufax S. Koufax	1	397	165	87	.655	314	2.76	2,396	137	40	9	2324.1	1,754	713	806	204	817	18	44	48	9,497	87	9.28	3.16	2.93	0.79	25.2	8.6	1.11	.256	3.12	6.79
19	Charlie Robertson C. Robertson	1	166	49	80	.380	141	4.45	312	59	6	1	1004.2	1,150	497	571	38	379	18	18		4,464	16	2.79	3.40	0.82	0.34	7.0	8.5	1.52	.299	5.12	10.30
20	Addie Joss A. Joss	1	88	43	29	.597	75		248	62	14	2	674.0	529		183	4	82	7	12		2,592	9	3.31	1.09	3.02	0.05	9.6	3.2	0.91	.233	2.44	7.06