Between the 2001 and 2015 seasons, LaTroy Hawkins threw in the most games, with 877 games.

Interpreted as:

most pitcher regular-season games from 2001 to 2015

	NAME	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	LaTroy Hawkins L. Hawkins	877	47	45	.511	0	3.27	625	0	0	113	858.1	842	312	343	70	235	9	334	31	3,577	37	6.55	2.46	2.66	0.73	17.5	6.6	1.25	.293	3.60	76	3.53	83	8.83	68.9
2	Francisco Rodriguez F. Rodriguez	859	47	44	.516	0	2.69	1,067	0	0	386	892.1	662	267	289	83	357	15	602	40	3,658	62	10.76	3.60	2.99	0.84	29.2	9.8	1.14	.271	2.91	65	3.15	76	6.68	102.2
3	Kyle Farnsworth K. Farnsworth	820	36	48	.429	0	3.91	819	0	0	56	781.2	714	340	371	90	310	21	284	28	3,331	33	9.43	3.57	2.64	1.04	24.6	9.3	1.31	.298	4.27	93	3.74	88	8.22	45.3
4	Mariano Rivera M. Rivera	783	49	43	.533	0	1.98	778	0	0	487	831.1	640	183	201	45	142	38	707	25	3,251	6	8.42	1.54	5.48	0.49	23.9	4.4	0.94	.265	2.18	45	2.55	58	6.93	167.8
5	Chad Qualls C. Qualls	781	49	47	.510	0	3.80	591	0	0	74	758.0	759	320	349	75	197	32	251	41	3,173	27	7.02	2.34	3.00	0.89	18.6	6.2	1.26	.300	4.14	93	3.73	90	9.01	36.3
6	Jeremy Affeldt J. Affeldt	774	43	46	.483	42	3.97	720	0	0	28	926.0	904	408	455	76	396	42	162	41	4,034	55	7.00	3.85	1.82	0.74	17.8	9.8	1.40	.296	4.42	92	4.00	95	8.79	21.3
7	Javier Lopez J. Lopez	771	29	14	.674	0	3.45	343	0	0	13	506.2	460	194	214	23	220	25	157	38	2,155	16	6.09	3.91	1.56	0.41	15.9	10.2	1.34	.283	3.80	81	3.77	93	8.17	15.1
8	Joe Nathan J. Nathan	738	50	28	.641	0	2.43	852	0	0	376	733.1	512	198	209	55	231	18	584	27	2,922	39	10.46	2.84	3.69	0.68	29.2	7.9	1.01	.259	2.57	58	2.75	66	6.28	119.2
9	Matt Thornton M. Thornton	730	35	46	.432	1	3.35	633	0	0	23	645.2	572	240	261	50	245	19	162	37	2,722	28	8.82	3.42	2.58	0.70	23.3	9.0	1.27	.294	3.64	77	3.36	78	7.97	68.2
10	Francisco Cordero F. Cordero	724	44	49	.473	0	3.18	728	0	0	329	728.1	645	257	284	51	309	23	558	25	3,095	29	9.00	3.82	2.36	0.63	23.5	10.0	1.31	.299	3.51	72	3.35	77	7.97	83.4
11	Fernando Rodney F. Rodney	700	37	55	.402	0	3.71	685	0	0	236	700.1	612	289	319	53	341	42	440	30	3,055	41	8.80	4.38	2.01	0.68	22.4	11.2	1.36	.289	4.10	89	3.76	90	7.86	31.7
12	Octavio Dotel O. Dotel	689	48	40	.545	4	3.32	916	0	0	93	740.2	569	273	299	79	302	28	279	35	3,093	37	11.13	3.67	3.03	0.96	29.6	9.8	1.18	.277	3.63	77	3.30	76	6.91	83.8
13	Rafael Betancourt R. Betancourt	680	38	37	.507	0	3.36	724	0	0	75	685.2	596	256	274	71	164	1	241	40	2,787	17	9.50	2.15	4.41	0.93	26.0	5.9	1.11	.287	3.60	76	3.04	71	7.82	92
14	Jason Frasor J. Frasor	679	35	35	.500	0	3.49	615	0	0	36	646.2	568	251	267	56	283	23	205	32	2,747	38	8.56	3.94	2.17	0.78	22.4	10.3	1.32	.289	3.72	80	3.73	87	7.91	40.9
15	Joe Beimel J. Beimel	676	29	34	.460	23	4.06	379	0	0	5	680.0	719	307	331	66	272	22	129	52	2,957	26	5.02	3.60	1.39	0.87	12.8	9.2	1.46	.294	4.38	97	4.52	107	9.52	-22.4
16	Guillermo Mota G. Mota	663	36	40	.474	0	3.93	645	0	0	10	771.1	681	337	351	82	294	20	187	47	3,235	30	7.53	3.43	2.19	0.96	19.9	9.1	1.26	.273	4.10	97	3.99	95	7.95	16.8
17	J.C. Romero	663	32	21	.604	11	3.89	472	0	0	7	594.0	539	257	280	51	345	39	125	47	2,636	33	7.15	5.23	1.37	0.77	17.9	13.1	1.49	.282	4.24	88	4.53	106	8.17	-15.6
18	Joaquin Benoit J. Benoit	661	54	42	.563	55	3.84	960	0	0	50	970.1	803	414	440	117	391	30	166	19	4,081	36	8.90	3.63	2.46	1.09	23.5	9.6	1.23	.266	4.08	85	3.96	91	7.45	38.4
19	Jonathan Papelbon J. Papelbon	652	39	32	.549	3	2.35	777	0	0	349	690.2	535	180	208	54	171	34	555	15	2,786	13	10.13	2.23	4.54	0.70	27.9	6.1	1.02	.275	2.71	56	2.76	68	6.97	103.5
20	Randy Choate R. Choate	650	16	13	.552	0	3.87	336	0	0	7	391.0	336	168	188	17	167	44	96	32	1,675	15	7.73	3.84	2.01	0.39	20.1	10.0	1.29	.287	4.33	94	3.53	86	7.73	25.3
21	Brian Fuentes B. Fuentes	650	26	43	.377	0	3.62	639	0	0	204	613.1	515	247	267	64	258	52	381	25	2,622	32	9.38	3.79	2.48	0.94	24.4	9.8	1.26	.280	3.92	81	3.86	88	7.56	37.4
22	David Weathers D. Weathers	644	39	47	.453	2	3.40	505	0	0	72	693.2	634	262	287	69	293	31	238	43	2,974	11	6.55	3.80	1.72	0.90	17.0	9.9	1.34	.272	3.72	79	4.31	98	8.23	6.8
23	Huston Street H. Street	638	39	32	.549	0	2.85	648	0	0	315	653.2	509	207	221	65	170	8	502	35	2,598	20	8.92	2.34	3.81	0.89	24.9	6.5	1.04	.260	3.04	68	3.22	79	7.01	66.4
24	Jose Valverde J. Valverde	626	27	33	.450	0	3.27	692	0	0	288	630.1	490	229	255	67	264	26	520	31	2,646	24	9.88	3.77	2.62	0.96	26.2	10.0	1.20	.265	3.64	76	3.65	85	7.00	45.6
25	Jonathan Broxton J. Broxton	608	39	35	.527	0	3.23	685	0	0	118	599.2	505	215	241	42	233	17	271	27	2,499	19	10.28	3.50	2.94	0.63	27.4	9.3	1.23	.304	3.62	80	2.99	73	7.58	76.8