Billy Hamilton has the most runs in a combined regular-season and postseason, with 198 runs in 1894.

Interpreted as:

most run by a player in a season include playoff

	NAME	R	SEASON	TM	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Billy Hamilton B. Hamilton	198	1894	PHI	132	558	225	25	15	4	90	128	9	19	100		702	292	44	7				.403	.521	.523	1.044	209	81.9	.495	157	76.2
2	Babe Ruth B. Ruth	180	1921	NYY	158	556	209	44	16	60	172	150	4	89	19		714	465	120	4				.376	.511	.836	1.348	214	127.8	.575	218	118.7
3	Tom Brown T. Brown	177	1891	BSA	137	589	189	30	21	5	72	70	4	96	106		663	276	56					.321	.397	.469	.865	139	42.6	.412	134	35.6
4	Lou Gehrig L. Gehrig	172	1936	NYY	161	603	212	38	7	51	159	133	8	48	3		747	417	96	3				.352	.474	.692	1.166	192	97.6	.512	171	85.8
5	Babe Ruth B. Ruth	172	1928	NYY	158	552	183	32	8	57	150	138	3	89	4		701	402	97	8				.332	.468	.728	1.196	174	90.6	.510	196	89.3
6	Tip O'Neill T. O'Neill	167	1887	STL	124	517	225	52	19	14	123	50	5	20	30		572	357	85					.435	.490	.691	1.180	191	96.4	.525	190	88.9
7	Billy Hamilton B. Hamilton	166	1895	PHI	123	517	201	22	6	7	74	96	7	30	97		629	256	35	9				.389	.490	.495	.985	167	63.2	.471	157	61.2
8	Willie Keeler W. Keeler	165	1894	BAL	129	590	219	27	22	5	94	40	18	6	32		664	305	54	16				.371	.427	.517	.944	156	36.1	.433	123	28.3
9	Joe Kelley J. Kelley	165	1894	BAL	129	507	199	48	20	6	111	107	5	36	46		638	305	74	19				.393	.502	.602	1.104	194	78.6	.502	159	71.1
10	Lou Gehrig L. Gehrig	163	1931	NYY	155	619	211	31	15	46	185	117	0	56	17	12	738	410	92	2				.341	.446	.662	1.108	179	87.7	.488	184	83.8
11	Arlie Latham A. Latham	163	1887	STL	136	627	198	35	10	2	83	45	5	29	129		677	259	47					.316	.366	.413	.779	131	19.7	.365	109	10.9
12	Babe Ruth B. Ruth	162	1927	NYY	155	555	198	29	8	62	172	139	0	91	8		709	429	99	14				.357	.486	.773	1.259	195	109.9	.545	207	104.8
13	Willie Keeler W. Keeler	162	1895	BAL	131	565	213	24	15	4	78	37	14	12	47		637	279	43	21				.377	.429	.494	.922	147	41.2	.432	134	37.1
14	Hugh Duffy H. Duffy	161	1890	CHP	137	596	191	36	16	7	82	59	2	20	78		657	280	59					.320	.384	.470	.853	137	36	.403	118	20.5
15	Rogers Hornsby R. Hornsby	160	1929	CHC	161	623	234	48	9	39	150	88	1	73	2		734	417	96	22				.376	.454	.669	1.123	181	86.8	.497	169	77.3
16	Jesse Burkett J. Burkett	160	1896	CLE	133	586	240	27	16	6	72	49	7	19	34		647	317	49	5				.410	.461	.541	1.002	163	63.9	.468	154	56.2
17	Hugh Duffy H. Duffy	160	1894	BSN	125	539	237	51	16	18	145	66	1	15	48		616	374	85	10				.440	.502	.694	1.196	203	91.3	.526	169	80.7
18	Fred Dunlap F. Dunlap	160	1884	SLU	101	449	185	39	8	13		29					478	279	60					.412		.621		143	73.6	.477	215	77.7
19	Babe Ruth B. Ruth	159	1923	NYY	158	541	212	46	14	44	133	178	4	99	17		726	418	104	3				.392	.545	.773	1.318	211	124.7	.571	222	120.4
20	Hughie Jennings H. Jennings	159	1895	BAL	131	529	204	41	7	4	125	24	32	17	53		613	271	52	28				.386	.444	.512	.957	150	49.1	.449	143	45.1
21	Chuck Klein C. Klein	158	1930	PHN	156	648	250	59	8	40	170	54	4	50	4		719	445	107	13				.386	.436	.687	1.123	181	80	.481	152	58.7
22	Babe Ruth B. Ruth	158	1920	NYY	142	458	172	36	9	54	135	150	3	80	14	14	616	388	99	5				.376	.532	.847	1.379	191	120.9	.597	237	110.5
23	Bobby Lowe B. Lowe	158	1894	BSN	133	613	212	34	11	17	115	50	6	25	23		678	319	62	9				.346	.401	.520	.921	147	24.6	.415	110	13
24	Lenny Dykstra L. Dykstra	157	1993	PHI	173	685	209	46	6	25	76	141	2	76	41	12	833	342	77	0	5	11	8	.305	.423	.499	.922	138	45.6	.400	133	41.5
25	Al Simmons A. Simmons	156	1930	PHA	144	576	219	43	16	38	169	41	1	36	9		635	408	97	17				.380	.422	.708	1.131	153	67.4	.480	167	63.8