The New York Yankees allowed their most runs in a game against the Cleveland Indians on July 29, 1928, with 24 runs.

Interpreted as:

most runs allowed regular-season game by yankees

	TEAM	R	DATE	TM		OPP	RESULT	ERA	SO	SHO	SV	IP	H	ER	HR	BB	HBP	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Yankees	24	7/29/1928	NYY	@	CLE	L 6-24	0.00	5	0	0	8.0	27	0	0	4	0		58	0	5.63	4.50	1.25	0.00	8.6	6.9	3.88	.551	27.00	30.38
2	Yankees	22	4/18/2009	NYY	vs	CLE	L 4-22	22.00	10	0	0	9.0	25	22	6	6	0	0	58	2	10.00	6.00	1.67	6.00	17.2	10.3	3.44	.528	22.00	25.00
3	Yankees	22	8/31/2004	NYY	vs	CLE	L 0-22	22.00	6	0	0	9.0	22	22	3	9	0	0	59	1	6.00	9.00	0.67	3.00	10.2	15.3	3.44	.463	22.00	22.00
4	Yankees	20	7/19/1987	NYY	@	TEX	L 3-20	22.50	4	0	0	8.0	22	20	3	5	0	0	49	0	4.50	5.63	0.80	3.38	8.2	10.2	3.38	.514	22.50	24.75
5	Yankees	19	8/15/2019	NYY	vs	CLE	L 5-19	19.00	8	0	0	9.0	24	19	7	4	1	0	54	0	8.00	4.00	2.00	7.00	14.8	7.4	3.11	.500	19.00	24.00
6	Yankees	19	7/25/2019	NYY	@	BOS	L 3-19	21.38	6	0	0	8.0	23	19	4	5	0	0	51	1	6.75	5.63	1.20	4.50	11.8	9.8	3.50	.528	21.38	25.88
7	Yankees	19	7/29/2006	NYY	vs	TBD	L 6-19	16.00	5	0	0	9.0	17	16	4	5	2	0	52	0	5.00	5.00	1.00	4.00	9.6	9.6	2.44	.361	19.00	17.00
8	Yankees	19	7/4/2006	NYY	@	CLE	L 1-19	20.25	6	0	0	8.0	21	18	6	6	1	0	52	0	6.75	6.75	1.00	6.75	11.5	11.5	3.38	.455	21.38	23.63
9	Yankees	19	8/29/1989	NYY	vs	OAK	L 5-19	13.00	6	0	0	9.0	18	13	2	5	1	0	52	2	6.00	5.00	1.20	2.00	11.5	9.6	2.56	.421	19.00	18.00
10	Yankees	19	9/10/1977	NYY	vs	TOR	L 3-19	11.00	1	0	0	9.0	20	11	3	2	0	0	51	0	1.00	2.00	0.50	3.00	2.0	3.9	2.44	.378	19.00	20.00
11	Yankees	19	9/29/1928	NYY	@	DET	L 10-19	0.00	2	0	0	8.0	27	0	2	3	1		54	0	2.25	3.38	0.67	2.25	3.7	5.6	3.75	.543	21.38	30.38
12	Yankees	19	6/17/1925	NYY	vs	DET	L 1-19	0.00	2	0	0	9.0	18	0	2	7	0		52	0	2.00	7.00	0.29	2.00	3.8	13.5	2.78	.390	19.00	18.00
13	Yankees	19	5/11/1925	NYY	@	SLA	L 10-19	0.00	1	0	0	8.0	17	0	1	14	0		53	2	1.13	15.75	0.07	1.13	1.9	26.4	3.88	.432	21.38	19.13
14	Highlanders	19	9/5/1912	NYH	vs	PHA	L 9-19	0.00	6	0	0	9.0	23	0	0	4	0		53	2	6.00	4.00	1.50	0.00	11.3	7.5	3.00	.535	19.00	23.00
15	Yankees	18	8/21/2007	NYY	@	LAA	L 9-18	20.25	6	0	0	8.0	17	18	2	9	0	0	49	1	6.75	10.13	0.67	2.25	12.2	18.4	3.25	.469	20.25	19.13
16	Yankees	18	6/8/1986	NYY	vs	BAL	L 9-18	17.00	4	0	0	9.0	22	17	4	8	0	0	55	0	4.00	8.00	0.50	4.00	7.3	14.5	3.33	.462	18.00	22.00
17	Yankees	18	7/19/1925	NYY	@	DET	L 12-18	0.00	0	0	0	8.0	22	0	1	5	2		53	1	0.00	5.63	0.00	1.13	0.0	9.4	3.38	.467	20.25	24.75
18	Highlanders	18	5/3/1912	NYH	@	PHA	L 15-18	0.00	6	0	0	8.0	16	0	0	8	1		52	2	6.75	9.00	0.75	0.00	11.5	15.4	3.00	.432	20.25	18.00
19	Yankees	17	6/20/2024	NYY	vs	BAL	L 5-17	13.00	7	0	0	9.0	20	13	3	7	2	0	58	0	7.00	7.00	1.00	3.00	12.1	12.1	3.00	.436	17.00	20.00
20	Yankees	17	9/27/2005	NYY	@	BAL	L 9-17	19.13	5	0	0	8.0	14	17	3	9	1	0	48	1	5.63	10.13	0.56	3.38	10.4	18.8	2.88	.367	19.13	15.75
21	Yankees	17	7/15/2005	NYY	@	BOS	L 1-17	19.13	5	0	0	8.0	15	17	2	9	0	0	48	0	5.63	10.13	0.56	2.25	10.4	18.8	3.00	.406	19.13	16.88
22	Yankees	17	5/28/2005	NYY	vs	BOS	L 1-17	17.00	5	0	0	9.0	27	17	3	2	1	0	57	0	5.00	2.00	2.50	3.00	8.8	3.5	3.22	.522	17.00	27.00
23	Yankees	17	9/13/2004	NYY	@	KCR	L 8-17	19.13	2	0	0	8.0	18	17	1	8	1	1	50	2	2.25	9.00	0.25	1.13	4.0	16.0	3.25	.447	19.13	20.25
24	Yankees	17	7/31/2002	NYY	@	TEX	L 6-17	15.75	3	0	0	8.0	21	14	4	3	0	0	47	1	3.38	3.38	1.00	4.50	6.4	6.4	3.00	.459	19.13	23.63
25	Yankees	17	6/18/2000	NYY	vs	CWS	L 4-17	17.00	9	0	0	9.0	18	17	1	12	0	0	57	0	9.00	12.00	0.75	1.00	15.8	21.1	3.33	.486	17.00	18.00