Mel Ott has put up the most career runs against the Pirates, with 285 runs.

Interpreted as:

most runs by a player scored vs pirates

	NAME	R	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Mel Ott M. Ott	285	406	1,377	436	65	7	83	305	280	12	116	18		1,685	764	155	16			7	.317	.436	.555	.991
2	Stan Musial S. Musial	275	426	1,546	526	108	27	58	253	238	5	79	14	4	1,806	862	193	8	9	21	31	.340	.428	.558	.985
3	Willie Mays W. Mays	251	343	1,253	405	62	23	76	234	177	2	129	40	9	1,443	741	161	1	10	36	41	.323	.405	.591	.996
4	Rogers Hornsby R. Hornsby	231	324	1,196	422	77	26	55		149	10	75	20		1,391	716	158	36				.353	.429	.599	1.027
5	Hank Aaron H. Aaron	229	348	1,350	420	59	11	78	244	110	2	133	24	6	1,479	735	148	2	15	33	41	.311	.360	.544	.905
6	Richie Ashburn R. Ashburn	209	308	1,199	389	47	16	2	99	143	6	64	36	12	1,373	474	65	24	1	7	11	.324	.399	.395	.794
7	Frankie Frisch F. Frisch	199	333	1,323	388	65	23	15	172	85	5	50	56		1,447	544	103	34				.293	.338	.411	.749
8	Pee Wee Reese P. Wee Reese	190	295	1,096	295	54	4	16	126	173	2	108	23	8	1,289	405	74	16	2	0	28	.269	.369	.370	.739
9	Pete Rose P. Rose	189	324	1,283	374	64	13	15	119	130	14	97	12	13	1,430	509	92	2	1	18	24	.292	.363	.397	.759
10	Eddie Mathews E. Mathews	187	299	1,079	297	46	13	73	217	166	1	177	10	7	1,259	588	132	4	9	18	19	.275	.370	.545	.915
11	Joe Medwick J. Medwick	186	279	1,078	356	85	20	20	189	45	5	67	11		1,134	541	125	6			13	.330	.360	.502	.862
12	Chuck Klein C. Klein	183	243	956	329	60	16	50	197	71	4	53	15		1,040	571	126	9			0	.344	.392	.597	.989
13	Lou Brock L. Brock	182	294	1,155	340	36	16	16	100	79	5	193	95	30	1,248	456	68	7	2	13	18	.294	.342	.395	.736
14	Duke Snider D. Snider	182	303	1,068	325	61	20	58	200	108	1	170	14	6	1,191	600	139	6	8	14	23	.304	.366	.562	.928
15	Red Schoendienst R. Schoendienst	178	310	1,168	347	59	11	13	107	84	7	47	12	3	1,270	467	83	9	2	0	22	.297	.347	.400	.747
16	Stan Hack S. Hack	174	285	1,089	337	54	15	7	109	158	2	58	27		1,266	442	76	17			7	.309	.398	.406	.804
17	Jackie Robinson J. Robinson	173	202	723	247	39	9	32	127	110	14	40	26	6	858	400	80	9	2	1	15	.342	.437	.553	.990
18	Billy Herman B. Herman	173	280	1,115	352	67	10	5	130	122	2	53	12		1,255	454	82	16			15	.316	.384	.407	.791
19	Bill Terry B. Terry	168	255	954	331	47	20	26	156	76	3	59	11		1,057	496	93	24				.347	.397	.520	.917
20	Mike Schmidt M. Schmidt	163	264	927	220	40	4	62	188	155	10	234	14	10	1,110	454	106	3	15	27	18	.237	.348	.490	.838
21	George Burns G. Burns	162	273	1,087	308	61	23	5	86	110	2	81	44		1,221	430	89	22				.283	.350	.396	.746
22	Ernie Banks E. Banks	159	323	1,209	344	51	12	57	187	85	7	134	10	7	1,315	590	120	1	13	26	36	.285	.332	.488	.820
23	Enos Slaughter E. Slaughter	159	265	1,007	324	55	27	17	190	131	3	52	10	0	1,150	484	99	9	0	0	17	.322	.401	.481	.882
24	Zack Wheat Z. Wheat	159	322	1,216	372	51	31	17		75	16	88	20		1,329	536	99	22				.306	.354	.441	.795
25	Alvin Dark A. Dark	158	256	1,023	296	57	11	15	106	57	2	88	4	1	1,099	420	83	14	3	1	18	.289	.327	.411	.738