Phil Niekro has allowed the most career runs, with 2,337 runs.

Interpreted as:

most runs scored while being no hit by a player

	NAME	R	NH	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Phil Niekro P. Niekro	2,337	1	864	318	274	.537	716	3.35	3,342	245	45	29	5404.0	5,044	2,012	482	1,809	123	83	86	22,677	227	5.57	3.01	1.85	0.80	14.7	8.0	1.27	.270	3.89	8.40
2	Nolan Ryan N. Ryan	2,178	7	807	324	292	.526	773	3.19	5,714	222	61	3	5386.0	3,923	1,911	321	2,795	158	13	78	22,575	277	9.55	4.67	2.04	0.54	25.3	12.4	1.25	.265	3.64	6.56
3	Steve Carlton S. Carlton	2,130	0	741	329	244	.574	709	3.22	4,136	254	55	2	5217.2	4,672	1,864	414	1,833	53	13	150	21,682	183	7.13	3.16	2.26	0.71	19.1	8.5	1.25	.279	3.67	8.06
4	Gaylord Perry G. Perry	2,128	1	777	314	265	.542	690	3.11	3,534	303	53	10	5350.0	4,938	1,846	399	1,378	108	33	163	21,953	160	5.95	2.32	2.56	0.67	16.1	6.3	1.18	.275	3.58	8.31
5	Red Ruffing R. Ruffing	2,117	0	624	273	225	.548	538	3.80	1,990	335	45	18	4341.1	4,288	1,835	254	1,542	57	69		18,525	46	4.13	3.20	1.29	0.53	10.7	8.3	1.34	.275	4.39	8.89
6	Don Sutton D. Sutton	2,104	0	774	324	256	.559	756	3.26	3,574	178	58	5	5282.1	4,692	1,914	472	1,343	82	12	103	21,631	112	6.09	2.29	2.66	0.80	16.5	6.2	1.14	.261	3.58	7.99
7	Jamie Moyer J. Moyer	2,076	0	696	269	209	.563	638	4.25	2,441	33	10	0	4074.0	4,231	1,926	522	1,155	146	15	69	17,356	57	5.39	2.55	2.11	1.15	14.1	6.7	1.32	.283	4.59	9.35
8	Ted Lyons T. Lyons	2,055	1	594	260	230	.531	484	3.67	1,072	356	27	25	4158.2	4,492	1,696	221	1,124	31	91		17,806	55	2.32	2.43	0.95	0.48	6.0	6.3	1.35	.278	4.45	9.72
9	Burleigh Grimes B. Grimes	2,048	0	616	270	212	.560	496	3.54	1,521	314	35	17	4177.0	4,420		149	1,297	97	94		17,974	92	3.28	2.79	1.17	0.32	8.5	7.2	1.37	.286	4.41	9.52
10	Jim Kaat J. Kaat	2,038	0	898	283	237	.544	625	3.45	2,462	180	31	17	4530.0	4,620	1,738	395	1,083	122	102	117	19,026	128	4.89	2.15	2.27	0.78	12.9	5.7	1.26	.282	4.05	9.18
11	Early Wynn E. Wynn	2,037	0	691	300	244	.551	611	3.54	2,340	289	49	15	4564.0	4,292	1,793	339	1,775	64	67		19,406	53	4.61	3.50	1.32	0.67	12.1	9.1	1.33	.266	4.02	8.46
12	Bert Blyleven B. Blyleven	2,029	1	692	287	250	.534	685	3.31	3,701	242	60	0	4970.0	4,632	1,830	430	1,322	155	3	71	20,492	114	6.70	2.39	2.80	0.78	18.1	6.5	1.20	.282	3.67	8.39
13	Warren Spahn W. Spahn	2,018	2	750	363	245	.597	665	3.09	2,583	382	63	28	5243.2	4,833	1,801	434	1,432	41	67		21,555	78	4.43	2.46	1.80	0.74	12.0	6.6	1.19	.258	3.46	8.30
14	Earl Whitehill E. Whitehill	2,018	0	541	218	185	.541	473	4.36	1,353	226	16	11	3564.0	3,915	1,728	192	1,431	102	46		15,773	43	3.42	3.61	0.95	0.48	8.6	9.1	1.50	.293	5.10	9.89
15	Tommy John T. John	2,017	0	760	288	231	.555	700	3.34	2,245	162	46	3	4710.0	4,783	1,749	302	1,259	98	22	102	19,691	188	4.29	2.41	1.78	0.58	11.4	6.4	1.28	.284	3.85	9.14
16	Sad Sam Jones S. Sam Jones	2,007	1	647	229	217	.513	488	3.84	1,220	250	36	31	3880.0	4,096		154	1,408	71	115			73	2.83	3.27	0.87	0.36		8.4	1.42	.284	4.66	9.50
17	Eppa Rixey E. Rixey	1,993	0	692	266	251	.515	554	3.15	1,351	289	37	14	4493.0	4,639		93	1,084	77	100			97	2.71	2.17	1.25	0.19		5.8	1.27	.281	3.99	9.29
18	Greg Maddux G. Maddux	1,981	0	744	355	227	.610	740	3.16	3,371	109	35	0	5008.1	4,726	1,756	353	999	137	3	177	20,421	70	6.06	1.80	3.37	0.63	16.5	4.9	1.14	.281	3.56	8.49
19	Robin Roberts R. Roberts	1,962	0	676	286	245	.539	609	3.40	2,362	305	45	25	4688.2	4,582	1,773	505	901	54	49		19,222	34	4.53	1.73	2.62	0.97	12.3	4.7	1.17	.265	3.77	8.80
20	Frank Tanana F. Tanana	1,910	0	638	240	236	.504	616	3.66	2,773	143	34	1	4188.1	4,063	1,702	448	1,255	129	10	116	17,641	119	5.96	2.70	2.21	0.96	15.7	7.1	1.27	.277	4.10	8.73
21	Bobo Newsom B. Newsom	1,908	0	600	211	222	.487	483	3.98	2,081	246	31	21	3759.1	3,768	1,664	207	1,734	61	71		16,483	60	4.98	4.15	1.20	0.50	12.6	10.5	1.46	.287	4.57	9.02
22	Tom Glavine T. Glavine	1,900	0	682	305	203	.600	682	3.54	2,607	56	25	0	4413.1	4,298	1,734	356	1,500	66	0	145	18,604	65	5.32	3.06	1.74	0.73	14.0	8.1	1.31	.280	3.87	8.76
23	Roger Clemens R. Clemens	1,885	0	709	354	184	.658	707	3.12	4,672	118	46	0	4916.2	4,185	1,707	363	1,580	159	0	63	20,240	143	8.55	2.89	2.96	0.66	23.1	7.8	1.17	.284	3.45	7.66
24	Walter Johnson W. Johnson	1,867	1	788	412	270	.604	654	1.73	3,456	520	108	34	5806.1	4,816		96	1,354	206	126			151	5.36	2.10	2.55	0.15		5.8	1.06	.261	2.89	7.46
25	Fergie Jenkins F. Jenkins	1,853	0	664	284	226	.557	594	3.34	3,191	267	49	7	4500.2	4,142	1,669	484	997	84	37	117	18,404	62	6.38	1.99	3.20	0.97	17.3	5.4	1.14	.268	3.71	8.28